Microbial Natural Product
Microbial natural products, primarily secondary metabolites produced by bacteria, fungi, and other microorganisms, remain a cornerstone of modern medicine and biotechnology. They form the foundation of numerous antibiotics (e.g., penicillin, streptomycin), anticancer agents, and immunosuppressants, addressing critical global health challenges like infectious diseases and cancer. Despite historical challenges such as compound rediscovery and complex biosynthesis, advances in genomics, metabolomics, and synthetic biology are unlocking novel chemical diversity from underexplored microbial sources. Consequently, microbial natural products continue to represent an unparalleled reservoir for discovering next-generation therapeutics, underscoring their enduring significance in drug development and sustainable bioprospecting. (98 words)
3-OαMycarosylerythronolide B
3-O-alpha-mycarosylerythronolide B is an erythronolide. 3-O-alpha-mycarosylerythronolide B is a natural product found in Apis cerana and Saccharopoly...
Acarbose
Formula: C25H43NO18 (645.248)
An inhibitor of alpha glucosidase that retards the digestion and absorption of carbohydrates in the small intestine and hence reduces the increase in ...
Streptonigrin
Formula: C25H22N4O8 (506.1438)
Complex cytotoxic antibiotic obtained from Streptomyces flocculus or S. rufochronmogenus. It is used in advanced carcinoma and causes leukopenia." []
Albonoursin
Formula: C15H16N2O2 (256.1212)
Albonoursin is a member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which the two hydrogen at position 3 and those at positi...
Delphinidin 3-O-rutinoside
Delphinidin 3-rutinoside is found in banana. Tulipanin is an anthocyanin. It is the 3-rutinoside of delphinidin. It can be found in Alstroemeria speci...
Macquarimicin A
Macquarimicin A has been reported in Micromonospora chalcea and Micromonospora with data available.
Macquarimicin B
Macquarimicin B is a pyranone. Macquarimicin B has been reported in Micromonospora chalcea with data available.
Indolmycin
Formula: C14H15N3O2 (257.1164)
Indolmycin is a member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted at the 2 and 5-pro-S positions by methylamino an...
Diazepinomicin
Formula: C28H34N2O4 (462.2518)
A dibenzodiazepine with a farnesyl sidechain synthesized by Micromonospora sp.. It has a potent activity against a broad spectrum of tumor cell lines....
N-cis-Caffeoyltyramine
N-cis-Caffeoyltyramine is found in fruits. N-cis-Caffeoyltyramine is an alkaloid from stems of cherimoya (Annona cherimola).
N-(p-Hydroxyphenyl)ethyl p-hydroxycinnamide
N-p-cis-Coumaroyltyramine is found in onion-family vegetables. N-p-cis-Coumaroyltyramine is a constituent of Chinese onion Allium chinense.
Isocorydine
(S)-Isocorydine is found in cherimoya. (S)-Isocorydine is an alkaloid from Peumus boldus (boldo
2,6-Dimethoxybenzoquinone
2,6-Dimethoxy-1,4-benzoquinone is found in common wheat. 2,6-Dimethoxy-1,4-benzoquinone is a constituent of bark of Phyllostachys heterocycla var. pub...
Isovanillin
Isovanillin is a member of the class of benzaldehydes that is 4-methoxybenzaldehyde substituted by a hydroxy group at position 3. It is an inhibitor o...
Kaur-16-en-18-oic acid
(-)-kaur-16-en-19-oic acid, also known as ent-kaurenoic acid or ent-kaur-16-en-19-oate, is a member of the class of compounds known as kaurane diterpe...
Isovanillic acid
Isovanillic acid is a metabolite of isovanillin. Isovanillin is a phenolic aldehyde, an organic compound and isomer of vanillin. It is a selective inh...
Acanthoside D
A beta-D-glucoside that is the 4,4'-bis(beta-D-glucosyl) derivative of (-)-syringaresinol." []
Eudesmic acid
Eudesmic acid is found in olive. Eudesmic acid is isolated from eucalyptus oil etc.
Syringaresinol
A lignan that is 7,9':7',9-diepoxylignane substituted by hydroxy groups at positions 4 and 4' and methoxy groups at positions 3, 3', 5 and 5' respecti...
Atherospermidine
Atherospermidine is an oxoaporphine alkaloid. Atherospermidine is a natural product found in Guatteria australis, Atherosperma moschatum, and other o...
Lysicamine
Lysicamine is an alkaloid antibiotic and an oxoaporphine alkaloid. It has a role as a metabolite.
Oxoxylopine
Oxoxylopine, also known as lanuginosine, is a member of the class of compounds known as aporphines. Aporphines are quinoline alkaloids containing the ...
N-Dihydroferuloyltyramine
N-Dihydroferuloyltyramine is found in fruits. N-Dihydroferuloyltyramine is an alkaloid from stems of cherimoya (Annona cherimola).
Laurotetanine
Laurotetanine is found in cherimoya. Laurotetanine is an alkaloid from the leaves of Peumus boldus (boldo
m-Chlorobenzoic acid
m-Chlorobenzoic acid is a metabolic byproduct of the drug bupropion. Bupropion is sold as Wellbutrin, or Zyban and is an atypical antidepressant that ...
Annolobine
Annolobine is an alkaloid antibiotic and an aporphine alkaloid. Anolobine is a natural product found in Magnolia officinalis, Goniothalamus amuyon, a...
(R)-Norisocorydine
(R)-Norisocorydine is found in fruits. (R)-Norisocorydine is an alkaloid from Annona cherimola (cherimoya
(+)-Pronuciferine
(R)-Pronuciferine is found in cherimoya. (R)-Pronuciferine is an alkaloid from Nelumbo nucifera (East India lotus
N-Methoxycarbonylanonaine
N-Methoxycarbonylanonaine is found in alcoholic beverages. N-Methoxycarbonylanonaine is an alkaloid from fresh unripe fruits of Rollinia mucosa (birib...
Cheritamine
Cheritamine is found in cherimoya. Cheritamine is an alkaloid from Annona cherimola (cherimoya
Oxoglaucine
Oxoglaucine is found in beverages. Oxoglaucine is an alkaloid from Annona purpurea (soncoya
Norisocorydine
Norisocorydine is found in cherimoya. Norisocorydine is an alkaloid from Peumus boldus (boldo
Annocherine B
Annocherine B is found in fruits. Annocherine B is an alkaloid from Annona cherimola (cherimoya
ent-Kauran-16βol
Ent-kauran-16-beta-ol is a member of the class of compounds known as kaurane diterpenoids. Kaurane diterpenoids are diterpene alkaloids with a structu...
16beta,17-dihydroxy-ent-kaurane-19-oic acid
16beta,17-dihydroxy-ent-kaurane-19-oic acid