Microbial Natural Product

Microbial natural products, primarily secondary metabolites produced by bacteria, fungi, and other microorganisms, remain a cornerstone of modern medicine and biotechnology. They form the foundation of numerous antibiotics (e.g., penicillin, streptomycin), anticancer agents, and immunosuppressants, addressing critical global health challenges like infectious diseases and cancer. Despite historical challenges such as compound rediscovery and complex biosynthesis, advances in genomics, metabolomics, and synthetic biology are unlocking novel chemical diversity from underexplored microbial sources. Consequently, microbial natural products continue to represent an unparalleled reservoir for discovering next-generation therapeutics, underscoring their enduring significance in drug development and sustainable bioprospecting. (98 words)


Isoprenyl alcohol

Formula: C5H10O (86.0732)

Methyl butenol is a colorless liquid. (USCG, 1999) 3-hydroxy-3-methylbut-1-ene is a tertiary alcohol that is 3-methylbut-1-ene carrying a hydroxy sub...

Prenol

Formula: C5H10O (86.0732)

Prenol is found in blackcurrant. Prenol is a constituent of ylang-ylang and hop oils. Prenol is found in orange peel oil and various fruits e.g. orang...

2-Hexadecanone

Formula: C16H32O (240.2453)

2-Hexadecanone is found in alcoholic beverages. 2-Hexadecanone is isolated from hop oil (Humulus lupulus

Kaempferol 3-neohesperidoside

Formula: C27H30O15 (594.1585)

Kaempferol 3-neohesperidoside is found in alcoholic beverages. Kaempferol 3-neohesperidoside is isolated from hop (Humulus lupulus).

beta-Selinene

Formula: C15H24 (204.1878)

beta-Selinene is found in alcoholic beverages. beta-Selinene is a constituent of celery oil. Also from Cyperus rotundus (nutgrass) and Humulus lupulus...

6-Methylheptanoic acid

Formula: C8H16O2 (144.115)

6-Methylheptanoic acid is found in alcoholic beverages. 6-Methylheptanoic acid is present in hop oil (Humulus lupulus) as the Me este

Isobutyl isobutyrate

Formula: C8H16O2 (144.115)

Isobutyl isobutyrate is found in alcoholic beverages. Isobutyl isobutyrate is present in apricot, banana, melon, strawberry and other fruits. Also pre...

Kaempferol-3-O-galactoside

Formula: C21H20O11 (448.1006)

Isoastragalin is found in fats and oils. Isoastragalin is isolated from Gossypium hirsutum (cotton) and other plant species.

Dhurrin

Formula: C14H17NO7 (311.1005)

Dhurrin is a cyanogenic glycoside occurring in plants. Its biosynthesis has been elucidated. Dhurrin is hydrolyzed in the stomach of an insect into a ...

Obtusifoliol

Formula: C30H50O (426.3861)

Obtusifoliol belongs to the class of organic compounds known as ergosterols and derivatives. These are steroids containing ergosta-5,7,22-trien-3beta-...

Cycloeucalenol

Formula: C30H50O (426.3861)

cycloeucalenol

Buphanidrine

Formula: C18H21NO4 (315.1471)

Buphandrin has been reported in Brunsvigia orientalis, Crinum latifolium, and other organisms with data available.

Patuletin

Formula: C16H12O8 (332.0532)

Patuletin is found in german camomile. Patuletin is a pigment from flowers of French marigold Tagetes patul

Apo-13-zeaxanthinone

Formula: C18H26O2 (274.1933)

Apo-13-zeaxanthinone is a member of the class of compounds known as sesquiterpenoids. Sesquiterpenoids are terpenes with three consecutive isoprene un...

(3R)-all-trans-3-Hydroxyretinal

Formula: C20H28O2 (300.2089)

Apo-15-zeaxanthinal, also known as (-)-(R)-all-trans-3-hydroxyretinal, is a member of the class of compounds known as retinoids. Retinoids are oxygena...

9-cis-Retinal

Formula: C20H28O (284.214)

In vivo, 9-cis-retinal is formed through oxidation of 9-cis-retinol by cis-retinol dehydrogenase (cRDH). (PMID:15572038). The generation of retinoic a...

Pomolic acid

Formula: C30H48O4 (472.3552)

Pomolic acid is found in apple. Pomolic acid is a constituent of apple peel

Kaempferol 3-glucuronide

Formula: C21H18O12 (462.0798)

Kaempferol 3-glucuronide is found in chicory. Kaempferol 3-glucuronide is isolated from the leaves of Euphorbia lathyris, Euphorbia cyparissias, Anemo...

Asiaticoside

Formula: C48H78O19 (958.5137)

Asiaticoside is found in green vegetables. Asiaticoside is a constituent of Centella asiatica (Asiatic pennywort)

Euscaphic acid

Formula: C30H48O5 (488.3502)

Euscaphic acid is found in herbs and spices. Euscaphic acid is a constituent of Coleus amboinicus (Cuban oregano).

ginsenoside Mx

Formula: C41H70O12 (754.4867)

A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions and in which...

Ginsenoside Mc

Formula: C41H70O12 (754.4867)

Ginsenoside Mc is considered to be practically insoluble (in water) and acidic

Ergothioneine

Formula: C9H15N3O2S (229.0885)

Ergothioneine is a naturally occurring metabolite of histidine that has antioxidant properties. -- Pubchem. Ergothioneine is a product of plant origin...

6beta-Hydroxyasiatic acid

Formula: C30H48O6 (504.3451)

6beta-Hydroxyasiatic acid is found in green vegetables. 6beta-Hydroxyasiatic acid is a constituent of Centella asiatica (Asiatic pennywort).

Methyl nicotinate

Formula: C7H7NO2 (137.0477)

Methyl nicotinate is found in alcoholic beverages. Methyl nicotinate is a flavouring ingredient. Methyl nicotinate is present in guava fruit, papaya, ...

Asiatic acid

Formula: C30H48O5 (488.3502)

A pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta ...

epi-Maslinic acid

Formula: C30H48O4 (472.3552)

epi-Maslinic acid

Ginsenoside Rg5

Formula: C42H70O12 (766.4867)

Ginsenoside Rg5 is found in tea. Ginsenoside Rg5 is isolated from ginsen

ginsenoside Rk1

Formula: C42H70O12 (766.4867)

ginsenoside Rk1 is a natural product found in Panax notoginseng, Panax ginseng, and Centella asiatica with data available.

Arjunolic acid

Formula: C30H48O5 (488.3502)

Arjunolic acid is found in fruits. Arjunolic acid is a constituent of Psidium guajava (guava)

Centellasaponin A

Formula: C48H78O19 (958.5137)

Centellasaponin A is found in green vegetables. Centellasaponin A is a constituent of Centella asiatica (Asiatic pennywort).

4-Hydroxy-3-(16-methylheptadecyl)-2H-pyran-2-one

Formula: C23H40O3 (364.2977)

4-Hydroxy-3-(16-methylheptadecyl)-2H-pyran-2-one is found in green vegetables. 4-Hydroxy-3-(16-methylheptadecyl)-2H-pyran-2-one is a constituent of Ce...

ginsenoside C-Y

Formula: C41H70O12 (754.4867)

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which th...

bayogenin

Formula: C30H48O5 (488.3502)

bayogenin

Ginsenoside Rg3

Formula: C42H72O13 (784.4973)

Ginsenoside Rg3

Madecassoside

Formula: C48H78O20 (974.5086)

Madecassoside is found in green vegetables. Madecassoside is isolated from whole plants of Centella asiatica (Ji Xue Cao).

1-Tuberculosinyladenosine

Formula: C30H46N5O4 (540.355)

|FRAME: CPD-23315 "1-tuberculosinyladenosine"| (1-TbAd) is a membrane permeable terpene nucleoside produced by many pathogenic mycobacterial species t...

Myristyl palmitate

Formula: C30H60O2 (452.4593)

Myristyl palmitate

3beta-Hydroxy-5-cholestenoate

Formula: C27H44O3 (416.329)

A steroid acid resulting from the oxidation of one of the terminal methyl groups of cholesterol to the corresponding aldehyde." []

Dendryphiellic acid A

Formula: C9H14O2 (154.0994)

Dendryphiellic acid A

PE(18:0(10(R)Me)/16:0)

Formula: C40H80NO8P (733.5621)

PE(18:0(10(R)Me)/16:0)

edaxadiene

Formula: C20H34O (290.261)

A bicyclic halimane-type diterpenoid produced by the pathogen Mycobacterium tuberculosis as a defense against macrophage attack. The structure was rev...

Alutacenoic acid A

Formula: C9H12O3 (168.0786)

Alutacenoic acid A

Bilobol

Formula: C21H34O2 (318.2559)

Bilobol

(3R,2'S)-Myxol 2'αL-fucoside

Formula: C46H66O7 (730.4808)

Myxol 2'-fucoside