Microbial Natural Product

Microbial natural products, primarily secondary metabolites produced by bacteria, fungi, and other microorganisms, remain a cornerstone of modern medicine and biotechnology. They form the foundation of numerous antibiotics (e.g., penicillin, streptomycin), anticancer agents, and immunosuppressants, addressing critical global health challenges like infectious diseases and cancer. Despite historical challenges such as compound rediscovery and complex biosynthesis, advances in genomics, metabolomics, and synthetic biology are unlocking novel chemical diversity from underexplored microbial sources. Consequently, microbial natural products continue to represent an unparalleled reservoir for discovering next-generation therapeutics, underscoring their enduring significance in drug development and sustainable bioprospecting. (98 words)


Lycopersene

Formula: C40H66 (546.5164)

Lycopersene

beta-D-Glucose

Formula: C6H12O6 (180.0634)

Glucose is a monosaccharide containing six carbon atoms and an aldehyde group. It is referred to as an aldohexose. The glucose molecule can exist in a...

8-O-Acetyl shanzhiside methyl ester

Formula: C19H28O12 (448.1581)

8-O-Acetyl shanzhiside methyl ester is a natural product found in Barleria lupulina, Lamium garganicum, and other organisms with data available.

Loganin

Formula: C17H26O10 (390.1526)

Loganin

Pinostrobin

Formula: C16H14O4 (270.0892)

A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively." []

Phloroglucinol

Formula: C6H6O3 (126.0317)

Phloroglucinol is a benzenetriol. It is an organic compound that is used in the synthesis of pharmaceuticals and explosives. This molecule exists in t...

Phloretin

Formula: C15H14O5 (274.0841)

Phloretin is the aglucone of phlorizin, a plant-derived dihydrochalcone phytochemical reported to promote potent antioxidative activities in peroxynit...

3-Methylbutanol

Formula: C5H12O (88.0888)

Isopentanol, also known as isoamyl alcohol or 3-methylbutanol, belongs to the class of organic compounds known as primary alcohols. Primary alcohols a...

2-Pentadecanone

Formula: C15H30O (226.2297)

2-Pentadecanone is found in cereals and cereal products. 2-Pentadecanone is isolated from hop (Humulus lupulus), coconut (Cocos nucifera) and other oi...

Lonchocarpol A

Formula: C25H28O5 (408.1937)

6,8-Diprenylnaringenin

Quercetin 3-O-(6-O-malonylβD-glucoside)

Formula: C24H22O15 (550.0959)

Quercetin 3-(6''-malonyl-glucoside) is found in endive. Quercetin 3-(6''-malonyl-glucoside) is isolated from Apocynum venetum and Salicornia europaea ...

Lupulone

Formula: C26H38O4 (414.277)

Lupulone is found in alcoholic beverages. Lupulone is a constituent of hops

Isolariciresinol 9-OβD-glucoside

Formula: C26H34O11 (522.2101)

Isolariciresinol 9-O-beta-D-glucoside is a constituent of Scots pine (Pinus sylvestris) needles.

Isodehydrocycloxanthohumol hydrate

Formula: C21H22O5 (354.1467)

Isodehydrocycloxanthohumol hydrate

alpha-Cadinene

Formula: C15H24 (204.1878)

alpha-Cadinene is found in alcoholic beverages. alpha-Cadinene is a constituent of Humulus lupulus (hops).

Xanthohumol C

Formula: C21H20O5 (352.1311)

Xanthohumol C is found in alcoholic beverages. Xanthohumol C is a constituent of the female inflorescence of hops (Humulus lupulus)

Xanthogalenol

Formula: C21H22O5 (354.1467)

Xanthogalenol is found in alcoholic beverages. Xanthogalenol is isolated from Humulus lupulus (hops

2-Oxohexane

Formula: C6H12O (100.0888)

2-Oxohexane, also known as hexan-2-one or MNBK, belongs to the class of organic compounds known as ketones. These are organic compounds in which a car...

3-Methylpentan-2-one

Formula: C6H12O (100.0888)

3-Methylpentan-2-one

6-Prenylnaringenin

Formula: C20H20O5 (340.1311)

(S)-4',5,7-Trihydroxy-6-prenylflavanone is found in alcoholic beverages. (S)-4',5,7-Trihydroxy-6-prenylflavanone is isolated from Humulus lupulus (hop...

Isohumulone A

Formula: C21H30O5 (362.2093)

Isohumulone B is found in alcoholic beverages. Isohumulone B is found in beer as isomer produced of Humulon

Humulone

Formula: C21H30O5 (362.2093)

An optically active cyclic ketone consisting of 3,5,6-trihydroxycyclohexa-2,4-dien-1-one bearing two 3-methylbut-2-en-1-yl substituents at positions 4...

4'-Methylacetophenone

Formula: C9H10O (134.0732)

4'-Methylacetophenone, also known as melilot or sweet clover, belongs to the class of organic compounds known as alkyl-phenylketones. These are aromat...

1,2,4-trithiane

Formula: C3H6S3 (137.9632)

1,2,4-trithiane is a trithiane. 1,2,4-Trithiane has been reported in Humulus lupulus with data available.

L-Pipecolate

Formula: C6H11NO2 (129.079)

Pipecolic acid is a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF. However, it is uncertain if pipecolic acid...

Xanthohumol E

Formula: C25H26O5 (406.178)

Xanthohumol E is found in alcoholic beverages. Xanthohumol E is a constituent of Humulus lupulus (hops)

(-)-Pinoresinol glucoside

Formula: C26H32O11 (520.1945)

(-)-pinoresinol is a member of the class of compounds known as lignan glycosides. Lignan glycosides are aromatic polycyclic compounds containing a car...

Methyl isobutyl ketone

Formula: C6H12O (100.0888)

Methyl isobutyl ketone (MIBK) is an organic solvent. MIBK is among the top ten most popular organic solvents used in industry. MIBK is occasionally fo...

Phlorizin

Formula: C21H24O10 (436.1369)

Phlorizin, also known as phlorizoside or phlorrhizen, belongs to the class of organic compounds known as flavonoid o-glycosides. Flavonoid O-glycoside...

4-Deoxycohumulone

Formula: C20H28O4 (332.1987)

4-Deoxycohumulone is found in alcoholic beverages. 4-Deoxycohumulone is a bitter principle from hops (Humulus lupulus).

p-Hydroxynonanophenone

Formula: C15H22O2 (234.162)

p-Hydroxynonanophenone is found in alcoholic beverages. p-Hydroxynonanophenone is a constituent of Humulus lupulus (hops).

Kaempferol 3-O-(6-malonyl-glucoside)

Formula: C24H22O14 (534.101)

Kaempferol 3-o-(6"-malonyl-glucoside) is a member of the class of compounds known as flavonoid-3-o-glycosides. Flavonoid-3-o-glycosides are phenolic c...

Xanthohumol B

Formula: C21H22O6 (370.1416)

Xanthohumol B is found in alcoholic beverages. Xanthohumol B is a constituent of hops (Humulus lupulus)

Methyl caprylate

Formula: C9H18O2 (158.1307)

Methyl caprylate is found in chinese cinnamon. Methyl caprylate is a flavouring agent. Methyl caprylate is present in many fruits, e.g. apple, apricot...

Hulupinic acid

Formula: C15H20O4 (264.1362)

Hulupinic acid is found in alcoholic beverages. Hulupinic acid is a constituent of hops

3-Methylbutanal

Formula: C5H10O (86.0732)

Iso-Valeraldehyde, also known as isoamyl aldehyde or 3-methyl-butanal, belongs to the class of organic compounds known as alpha-hydrogen aldehydes. Th...

3-Methyl-2-butenal

Formula: C5H8O (84.0575)

An enal consisting of but-2-ene with a methyl substituent at position 3 and an oxo group at position 1." []

4-Deoxyhumulone

Formula: C21H30O4 (346.2144)

4-Deoxyhumulone is found in alcoholic beverages. 4-Deoxyhumulone is isolated from hops (Humulus lupulus).

Quercetin 3-O-neohesperidoside

Formula: C27H30O16 (610.1534)

Quercetin 3-o-neohesperidoside is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Quercetin 3-o-neohesperidoside ca...

4-Heptenoic acid

Formula: C7H12O2 (128.0837)

4-Heptenoic acid is found in alcoholic beverages. 4-Heptenoic acid is isolated as the Me ester from oil of Humulus lupulus (hops).

2',4,4'-Trihydroxy-6'-methoxy-3',5'-diprenylchalcone

Formula: C26H30O5 (422.2093)

2',4,4'-Trihydroxy-6'-methoxy-3',5'-diprenylchalcone is found in alcoholic beverages. 2',4,4'-Trihydroxy-6'-methoxy-3',5'-diprenylchalcone is a consti...

3-Methylbutan-2-one

Formula: C5H10O (86.0732)

3-Methylbutan-2-one

alpha-Corocalene

Formula: C15H20 (200.1565)

alpha-Corocalene is found in alcoholic beverages. alpha-Corocalene is a constituent of the oil of hops (Humulus lupulus).

Xanthohumol D

Formula: C21H22O6 (370.1416)

Xanthohumol D is found in alcoholic beverages. Xanthohumol D is isolated from Humulus lupulus (hops

3'-Geranyl-2',4,4',6'-tetrahydroxychalcone

Formula: C25H28O5 (408.1937)

3'-Geranyl-2',4,4',6'-tetrahydroxychalcone is found in alcoholic beverages. 3'-Geranyl-2',4,4',6'-tetrahydroxychalcone is a constituent of hops (Humul...

4'-O-Methylxanthohumol

Formula: C22H24O5 (368.1624)

4'-O-methylxanthohumol is a member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' and 4, methoxy group...

Haginin A

Formula: C17H16O5 (300.0998)

Haginin A