Microbial Natural Product

Microbial natural products, primarily secondary metabolites produced by bacteria, fungi, and other microorganisms, remain a cornerstone of modern medicine and biotechnology. They form the foundation of numerous antibiotics (e.g., penicillin, streptomycin), anticancer agents, and immunosuppressants, addressing critical global health challenges like infectious diseases and cancer. Despite historical challenges such as compound rediscovery and complex biosynthesis, advances in genomics, metabolomics, and synthetic biology are unlocking novel chemical diversity from underexplored microbial sources. Consequently, microbial natural products continue to represent an unparalleled reservoir for discovering next-generation therapeutics, underscoring their enduring significance in drug development and sustainable bioprospecting. (98 words)


Abietal

Formula: C20H30O (286.2297)

Abietinal is a constituent of Pinus sylvestris (Scotch pine)

Abietinol

Formula: C20H32O (288.2453)

Abietinol is isolated from Pinus sylvestris (Scotch pine

3',4',5'-Trimethoxycinnamyl alcohol

Formula: C12H16O4 (224.1049)

3',4',5'-Trimethoxycinnamyl alcohol is found in herbs and spices. 3',4',5'-Trimethoxycinnamyl alcohol is a constituent of Myristica fragrans (nutmeg) ...

Isopimaric acid

Formula: C20H30O2 (302.2246)

Isopimaric acid is isolated from Pinus palustris (pitch pine).

Hinokinin

Formula: C20H18O6 (354.1103)

A lignan that is dihydrofuran-2(3H)-one (gamma-butyrolactone) substituted by a 3,4-methylenedioxybenzyl group at positions 3 and 4 (the 3R,4R-diastere...

Skimmianine

Formula: C14H13NO4 (259.0845)

Skimmianine is an organonitrogen heterocyclic compound, an organic heterotricyclic compound, an oxacycle and an alkaloid antibiotic. Skimmianine is a...

Estragole

Formula: C10H12O (148.0888)

1-Methoxy-4-(2-propenyl)benzene, also known as methylchavicol or estragol, belongs to the class of organic compounds known as anisoles. These are orga...

Hydroxyαsanshool

Formula: C16H25NO2 (263.1885)

Hydroxy-alpha-sanshool is found in herbs and spices. Hydroxy-alpha-sanshool is a constituent of Zanthoxylum piperitum (Japanese pepper tree)

Hydroxy-gamma-sanshool

Formula: C18H27NO2 (289.2042)

Hydroxy-gamma-sanshool

N-Acetylanonaine

Formula: C19H17NO3 (307.1208)

N-Acetylanonaine is found in fruits. N-Acetylanonaine is an alkaloid from the root bark of Zanthoxylum simulans (Szechuan pepper

Guaijaverin

Formula: C20H18O11 (434.0849)

Quercetin-3-D-xyloside;Reinutrin is a natural product found in Rosa multiflora, Toxicodendron wallichii, and other organisms with data available.

Isorhamnetin 7-glucoside

Formula: C22H22O12 (478.1111)

Isorhamnetin 7-glucoside is found in brassicas. Isorhamnetin 7-glucoside is isolated from various plants including Brassica napus (oilseed rape

5-O-Feruloylquinic acid

Formula: C17H20O9 (368.1107)

3-Feruloylquinic acid (3-FQA) (CAS: 1899-29-2) belongs to the class of organic compounds known as quinic acids and derivatives. Quinic acids and deriv...

Nitidine

Formula: C21H18NO4 (348.1236)

Nitidine is a member of phenanthridines. Nitidine is a natural product found in Zanthoxylum ailanthoides, Zanthoxylum gilletii, and other organisms w...

Norchelerythrine

Formula: C20H15NO4 (333.1001)

Norchelerythrine is a benzophenanthridine alkaloid. Norchelerythrine is a natural product found in Zanthoxylum simulans, Zanthoxylum ailanthoides, an...

Dillenetin 7-glucoside

Formula: C23H24O12 (492.1268)

Dillenetin 7-glucoside

(+/-)-[R-(E)]-5-Isopropyl-8-methylnona-6,8-dien-2-one

Formula: C13H22O (194.1671)

(+/-)-[R-(E)]-5-Isopropyl-8-methylnona-6,8-dien-2-one is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http...

(+)-Linalool

Formula: C10H18O (154.1358)

(R)-3,7-Dimethyl-1,6-octadien-3-ol is found in coriander. (R)-3,7-Dimethyl-1,6-octadien-3-ol is a constituent of many essential oils including Melissa...

Bisanhydrobacterioruberin

Formula: C50H72O2 (704.5532)

A C50 carotenoid that is an intermediate in the biosynthesis of bacterioruberin, a red-coloured pigment found in several Halobacterium and Haloarcula ...

Kaempferol 3αD-galactoside

Formula: C21H20O11 (448.1006)

Kaempferol 3-alpha-D-galactoside

Monoanhydrobacterioruberin

Formula: C50H74O3 (722.5638)

A C50 carotenoid that is an intermediate in the biosynthesis of bacterioruberin, a red-coloured pigment found in several Halobacterium and Haloarcula ...

decaprenoxanthin monoglucoside

Formula: C56H82O7 (866.606)

This compound was observed experimentally in |FRAME: TAX-853| (unpublished data, X. Feng, University Medical Center Groningen).

Decaprenoxanthin diglucoside

Formula: C62H92O12 (1028.6588)

Decaprenoxanthin diglucoside

7-O-Methylwogonin

Formula: C17H14O5 (298.0841)

7-O-Methylwogonin

5,2',6'-Trihydroxy-7-methoxyflavone

Formula: C16H12O6 (300.0634)

5,2',6'-Trihydroxy-7-methoxyflavone

Genkwanin

Formula: C16H12O5 (284.0685)

Genkwanin

8-O-Acetylharpagide

Formula: C17H26O11 (406.1475)

8-O-Acetylharpagide is an iridoid monoterpenoid and a glycoside.

Harpagide

Formula: C15H24O10 (364.1369)

Harpagide is an iridoid monoterpenoid and a glycoside.

3-Hydroxyisorenieratene

Formula: C40H48O (544.3705)

3-Hydroxyisorenieratene

Dihydromyricetin

Formula: C15H12O8 (320.0532)

Dihydromyricetin

Geranyl acetate

Formula: C12H20O2 (196.1463)

Neryl acetate is found in cardamom. Neryl acetate is found in citrus, kumquat and pummelo peel oils, ginger, cardamon, clary sage, myrtle leaf and myr...

Fraxetin

Formula: C10H8O5 (208.0372)

A hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups." []

Calamenene

Formula: C15H22 (202.1721)

Calamenene belongs to the class of organic compounds known as sesquiterpenoids. These are terpenes with three consecutive isoprene units.

Ascaridole

Formula: C10H16O2 (168.115)

Ascaridole is found in cardamom. Said to be the major constituent of oil of Peumus boldus (boldo).Ascaridole is a natural organic compound classified ...

p-Mentha-1,3,8-triene

Formula: C10H14 (134.1095)

p-Mentha-1,3,8-triene is found in dill. p-Mentha-1,3,8-triene is isolated from Petroselinum sativum (Yugoslavian parsley).

Myricetin 3,7,3',5'-tetramethyl ether

Formula: C19H18O8 (374.1002)

Myricetin 3,7,3',5'-tetramethyl ether

Allo-Aromadendrene

Formula: C15H24 (204.1878)

(-)-allo-Aromadendrene

p-Mentha-1,5-dien-7-ol

Formula: C10H16O (152.1201)

P-mentha-1,5-dien-7-ol is a member of the class of compounds known as menthane monoterpenoids. Menthane monoterpenoids are monoterpenoids with a struc...

5-Hydroxy-4',7-dimethoxy-6-methylflavone

Formula: C18H16O5 (312.0998)

5-Hydroxy-4',7-dimethoxy-6-methylflavone is found in beverages. 5-Hydroxy-4',7-dimethoxy-6-methylflavone is isolated from Gaultheria procumbens (winte...

delta-Cadinene

Formula: C15H24 (204.1878)

(+)-1(10),4-Cadinadiene is found in allspice. (+)-1(10),4-Cadinadiene is a constituent of the essential oils of ylang-ylang, citronella, cubebs, and s...

Bornyl acetate

Formula: C12H20O2 (196.1463)

(-)-alpha-Fenchyl acetate is a flavouring ingredient, together with stereoisomers.

C.p.450

Formula: C50H72O2 (704.5532)

C.p.450

Decaprenoxanthin

Formula: C50H72O2 (704.5532)

Decaprenoxanthin

Tetramethylpyrazine

Formula: C8H12N2 (136.1)

Tetramethylpyrazine, or 2,3,5,6-tetramethylpyrazine, or TMP and also known as FEMA 3237, is an alkylpyrazine and belongs to the class of organic comp...

Totaradiol

Formula: C20H30O2 (302.2246)

Totaradiol has been reported in Chamaecyparis formosensis, Thuja plicata, and other organisms with data available.

(+)-Pimaric acid

Formula: C20H30O2 (302.2246)

(+)-Pimaric acid is a diterpenoid. Pimaric acid is a natural product found in Abies holophylla, Pinus nigra, and other organisms with data available.