Microbial Natural Product
Microbial natural products, primarily secondary metabolites produced by bacteria, fungi, and other microorganisms, remain a cornerstone of modern medicine and biotechnology. They form the foundation of numerous antibiotics (e.g., penicillin, streptomycin), anticancer agents, and immunosuppressants, addressing critical global health challenges like infectious diseases and cancer. Despite historical challenges such as compound rediscovery and complex biosynthesis, advances in genomics, metabolomics, and synthetic biology are unlocking novel chemical diversity from underexplored microbial sources. Consequently, microbial natural products continue to represent an unparalleled reservoir for discovering next-generation therapeutics, underscoring their enduring significance in drug development and sustainable bioprospecting. (98 words)
2,4-Di-tert-butylphenol
2,4-Di-tert-butylphenol, also known as 2,4-DTBP, belongs to the class of organic compounds known as phenylpropanes. These are organic compounds contai...
Spathulenol
Spathulenol is found in alcoholic beverages. Spathulenol is a constituent of Salvia sclarea (clary sage).
Epicatechin-(4beta->8)-epigallocatechin 3'-gallate
Epicatechin-(4beta->8)-epigallocatechin 3'-gallate is a member of the class of compounds known as biflavonoids and polyflavonoids. Biflavonoids and po...
6'-O-Malonylwistin
6''-O-Malonylwistin is found in pulses. 6''-O-Malonylwistin is isolated from Medicago sativa (alfalfa).
Ellagic acid
Ellagic acid is an organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intram...
beta-Amyrenone
Beta-amyrenone is a member of the class of compounds known as triterpenoids. Triterpenoids are terpene molecules containing six isoprene units. Beta-a...
euphorbia factor L1
Euphorbia factor L1 is a natural product found in Euphorbia lathyris with data available.
6beta-Hydroxystigmast-4-en-3-one
6beta-hydroxystigmast-4-en-3-one is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 6beta-hydroxystigmast-4-en...
Oleuropein
A secoiridoid glycoside that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, e...
2-(10-Heptadecenyl)-6-hydroxybenzoic acid
2-(10-Heptadecenyl)-6-hydroxybenzoic acid is found in fats and oils. 2-(10-Heptadecenyl)-6-hydroxybenzoic acid is isolated from Ginkgo biloba (ginkgo)...
Bufotenine
A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of s...
Tupuseleiamide B
Formula: C21H32N2O6 (408.226)
Sulfisoxazole
Formula: C11H13N3O3S (267.0678)
Sulfisoxazole is only found in individuals that have used or taken this drug. It is a short-acting sulfonamide antibacterial with activity against a w...
3-Phosphonopyruvate
A 2-oxo monocarboxylic acid that is pyruvic acid substituted at position 3 by a phospho group." []
Swertiamarin
Swertiamaroside is a glycoside. Swertiamaroside is a natural product found in Gentiana macrophylla, Gentiana cephalantha, and other organisms with da...
Swertiajaponin
Swertiajaponin is found in green vegetables. Swertiajaponin is a constituent of leaves of Gnetum gnemon (bago)
Crispine D
Formula: C20H31N7O2 (401.2539)
Atromentin
A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxycyclohexa-2,5-diene-1,4-dione which is substituted by a 4-hydroxyphenyl grou...
Osmundalactone
Osmundalactone is found in root vegetables. Osmundalactone is a constituent of Osmunda japonica (zenmai)
Xerocomic acid
Xerocomic acid is found in mushrooms. Xerocomic acid is isolated from Boletus erythropus (dotted-stem bolete) and Gomphidius glutinosus (spike cap
3,4-dimethoxycinnamyl alcohol
A primary alcohol that is cinnamyl alcohol substituted by methoxy groups at positions 3' and 4' respectively." []
Cytidine 2'-phosphate
Formula: C9H14N3O8P (323.0518)
Cytidine 2'-phosphate is a cytidine nucleotide containing a phosphate group esterified to C2 of the sugar moiety. Cytidine 2'-phosphate is a product o...
Dihydroanhydropodorhizol
A member of the class of butan-4-olides carrying 3,4,5-trimethoxybenzyl and (1,3-benzodioxol-5-yl)methyl substituents at positions 3 and 4 respectivel...