Pathways Knowlegdes
Biological pathway database
| Pathway | DOIs | Note |
|---|---|---|
| pantothenate and coenzyme A biosynthesis Accession ID: BioCyc:CALBI_PWY3B3-1588 |
|
Webb ME, Smith AG, Abell C. Biosynthesis of pantothenate. Nat Prod Rep. 2004 Dec;21(6):695–721. doi: 10.1039/b316419p. PMID: 15565250.; White WH, Gunyuzlu PL, Toyn JH. Saccharomyces cerevisiae is capable of de Novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine. J Biol Chem. 2001 Apr 06;276(14):10794–800. doi: 10.1074/jbc.m009804200. PMID: 11154694.; Sarett HP, Cheldelin VH. The Utilization of beta-Alanine and Pantothenic Acid by Yeasts. J Bacteriol. 1945 Jan;49(1):31–9. PMID: 16560893; PMCID: PMC517986. |
| salvage pathways of adenine, hypoxanthine, and their nucleosides Accession ID: BioCyc:CALBI_SALVADEHYPOX-PWY |
|
Rolfes RJ. Regulation of purine nucleotide biosynthesis: in yeast and beyond. Biochem Soc Trans. 2006 Nov;34(Pt 5):786–90. doi: 10.1042/bst0340786. PMID: 17052198.; Itoh R, Saint-Marc C, Chaignepain S, Katahira R, Schmitter J, Daignan-Fornier B. The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase. BMC Molecular and Cell Biology. 2003 May 07;4(1):4. doi: 10.1186/1471-2091-4-4.; Escobar-Henriques M, Daignan-Fornier B. Transcriptional Regulation of the Yeast GMP Synthesis Pathway by Its End Products. Journal of Biological Chemistry. 2001 Jan;276(2):1523–30. doi: 10.1074/jbc.m007926200.; Challa A, Johnson S, Robertson K, Gunasekaran M. Properties of adenosine deaminase from Candida albicans. J Basic Microbiol. 1999;39(2):97–101. doi: 10.1002/(sici)1521-4028(199905)39:2<97::aid-jobm97>3.0.co;2-n. PMID: 10335602.; Guetsova ML, Lecoq K, Daignan-Fornier B. The isolation and characterization of Saccharomyces cerevisiae mutants that constitutively express purine biosynthetic genes. Genetics. 1997 Oct;147(2):383–97. PMID: 9335580; PMCID: PMC1208165.; Deeley MC. Adenine deaminase and adenine utilization in Saccharomyces cerevisiae. J Bacteriol. 1992 May;174(10):3102–10. doi: 10.1128/jb.174.10.3102-3110.1992. |
| purine nucleotides de novo biosynthesis Accession ID: BioCyc:CALBI_DENOVOPURINE2-PWY |
|
Rodriguez-Suarez R, Xu D, Veillette K, Davison J, Sillaots S, Kauffman S, Hu W, Bowman J, Martel N, Trosok S, Wang H, Zhang L, Huang LY, Li Y, Rahkhoodaee F, Ransom T, Gauvin D, Douglas C, Youngman P, Becker J, Jiang B, Roemer T. Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus. Chem Biol. 2007 Oct;14(10):1163–75. doi: 10.1016/j.chembiol.2007.09.009. PMID: 17961828.; Rolfes RJ. Regulation of purine nucleotide biosynthesis: in yeast and beyond. Biochem Soc Trans. 2006 Nov;34(Pt 5):786–90. doi: 10.1042/bst0340786. PMID: 17052198.; Köhler GA, White TC, Agabian N. Overexpression of a cloned IMP dehydrogenase gene of Candida albicans confers resistance to the specific inhibitor mycophenolic acid. J Bacteriol. 1997 Apr;179(7):2331–8. doi: 10.1128/jb.179.7.2331-2338.1997.; Poulter RT, Rikkerink EH. Genetic analysis of red, adenine-requiring mutants of Candida albicans. J Bacteriol. 1983 Dec;156(3):1066–77. doi: 10.1128/jb.156.3.1066-1077.1983. |
| PRPP biosynthesis I Accession ID: BioCyc:LEISH_PWY0-662 |
- | |
| tRNA charging pathway Accession ID: BioCyc:LEISH_TRNA-CHARGING-PWY |
- | |
| superpathway of glycolysis, pyruvate dehydrogenase and TCA cycle Accession ID: BioCyc:LEISH_PWY3IU-61 |
- | |
| oxidative ethanol degradation III (microsomal) Accession ID: BioCyc:TRYPANO_PWY66-161 |
- | |
| superpathway of glycolysis and Entner-Doudoroff Accession ID: BioCyc:TRYPANO_GLYCOLYSIS-E-D |
- | |
| glycolysis II Accession ID: BioCyc:TRYPANO_PWY-5484 |
- | |
| superpathway of aspartate and asparagine biosynthesis; interconversion of aspartate and asparagine Accession ID: BioCyc:TRYPANO_ASPASN-PWY |
- | |
| adenosine nucleotides de novo biosynthesis Accession ID: BioCyc:TRYPANO_PWY-6126 |
- | |
| superpathway of arginine and polyamine biosynthesis Accession ID: BioCyc:TRYPANO_ARG+POLYAMINE-SYN |
- | |
| NAD biosynthesis II (from tryptophan) Accession ID: BioCyc:TRYPANO_NADSYN-PWY |
- | |
| NAD biosynthesis I (from aspartate) Accession ID: BioCyc:TRYPANO_PYRIDNUCSYN-PWY |
- | |
| mycothiol biosynthesis Accession ID: BioCyc:TRYPANO_PWY1G-0 |
- | |
| selenocysteine biosynthesis I (bacteria) Accession ID: BioCyc:TRYPANO_PWY0-901 |
- | |
| gluconeogenesis I Accession ID: BioCyc:TRYPANO_GLUCONEO-PWY |
- | |
| NAD biosynthesis (from tryptophan) Accession ID: BioCyc:CALBI_NADSYN-PWY |
|
Li YF, Bao WG. Why do some yeast species require niacin for growth? Different modes of NAD synthesis. FEMS Yeast Res. 2007 Aug;7(5):657–64. doi: 10.1111/j.1567-1364.2007.00231.x. PMID: 17425674.; Belenky P, Bogan KL, Brenner C. NAD+ metabolism in health and disease. Trends Biochem Sci. 2007 Jan;32(1):12–9. doi: 10.1016/j.tibs.2006.11.006. PMID: 17161604.; Chaffin WL, Barton RA, Jacobson EL, Jacobson MK. Nicotinamide adenine dinucleotide metabolism in Candida albicans. J Bacteriol. 1979 Sep;139(3):883–8. doi: 10.1128/jb.139.3.883-888.1979. |
| salvage pathways of purine nucleosides Accession ID: BioCyc:CALBI_P121-PWY |
|
Rolfes RJ. Regulation of purine nucleotide biosynthesis: in yeast and beyond. Biochem Soc Trans. 2006 Nov;34(Pt 5):786–90. doi: 10.1042/bst0340786. PMID: 17052198.; Challa A, Johnson S, Robertson K, Gunasekaran M. Properties of adenosine deaminase from Candida albicans. J Basic Microbiol. 1999;39(2):97–101. doi: 10.1002/(sici)1521-4028(199905)39:2<97::aid-jobm97>3.0.co;2-n. PMID: 10335602. |
| NAD salvage pathway Accession ID: BioCyc:CALBI_PWY3O-4107 |
|
Li YF, Bao WG. Why do some yeast species require niacin for growth? Different modes of NAD synthesis. FEMS Yeast Res. 2007 Aug;7(5):657–64. doi: 10.1111/j.1567-1364.2007.00231.x. PMID: 17425674.; Belenky P, Bogan KL, Brenner C. NAD+ metabolism in health and disease. Trends Biochem Sci. 2007 Jan;32(1):12–9. doi: 10.1016/j.tibs.2006.11.006. PMID: 17161604.; Anderson RM, Bitterman KJ, Wood JG, Medvedik O, Cohen H, Lin SS, Manchester JK, Gordon JI, Sinclair DA. Manipulation of a Nuclear NAD+ Salvage Pathway Delays Aging without Altering Steady-state NAD+ Levels. Journal of Biological Chemistry. 2002 May;277(21):18881–90. doi: 10.1074/jbc.m111773200.; Chaffin WL, Barton RA, Jacobson EL, Jacobson MK. Nicotinamide adenine dinucleotide metabolism in Candida albicans. J Bacteriol. 1979 Sep;139(3):883–8. doi: 10.1128/jb.139.3.883-888.1979. |