Pathways Knowlegdes
Biological pathway database
| Pathway | DOIs | Note |
|---|---|---|
| molybdenum cofactor biosynthesis Accession ID: BioCyc:LEISH_PWY-5354 |
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| NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde Accession ID: BioCyc:LEISH_PWY-5653 |
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| salvage pathways of purine nucleosides Accession ID: BioCyc:LEISH_PWY3IU-402 |
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Boitz JM, Ullman B. A Conditional Mutant Deficient in Hypoxanthine-guanine Phosphoribosyltransferase and Xanthine Phosphoribosyltransferase Validates the Purine Salvage Pathway of Leishmania donovani. Journal of Biological Chemistry. 2006 Jun;281(23):16084–9. doi: 10.1074/jbc.m600188200.; Jardim A, Bergeson SE, Shih S, Carter N, Lucas RW, Merlin G, Myler PJ, Stuart K, Ullman B. Xanthine phosphoribosyltransferase from Leishmania donovani. Molecular cloning, biochemical characterization, and genetic analysis. J Biol Chem. 1999 Nov 26;274(48):34403–10. doi: 10.1074/jbc.274.48.34403. PMID: 10567419.; Rainey PM, Spithill TW, McMahon-Pratt D, Pan AA. Biochemical and molecular characterization ofLeishmania pifanoi amastigotes in continuous axenic culture. Molecular and Biochemical Parasitology. 1991 Nov;49(1):111–8. doi: 10.1016/0166-6851(91)90134-r.; LaFon SW, Nelson DJ, Berens RL, Marr JJ. Purine and pyrimidine salvage pathways in Leishmania donovani. Biochem Pharmacol. 1982 Jan 15;31(2):231–8. doi: 10.1016/0006-2952(82)90216-7. PMID: 7059364. |
| urea cycle Accession ID: BioCyc:LEISH_PWY-4984 |
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| ethanol degradation II (cytosol) Accession ID: BioCyc:LEISH_PWY66-21 |
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| superpathway of acetate utilization and formation Accession ID: BioCyc:TRYPANO_ACETATEUTIL-PWY |
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| phenylacetate degradation I (aerobic) Accession ID: BioCyc:TRYPANO_PWY0-321 |
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| fatty acid β-oxidation I Accession ID: BioCyc:TRYPANO_FAO-PWY |
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| salvage pathways of adenine, hypoxanthine, and their nucleosides Accession ID: BioCyc:TRYPANO_SALVADEHYPOX-PWY |
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| ethanol degradation II (cytosol) Accession ID: BioCyc:TRYPANO_PWY66-21 |
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| glycolysis I Accession ID: BioCyc:TRYPANO_GLYCOLYSIS |
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| arginine biosynthesis I Accession ID: BioCyc:TRYPANO_ARGSYN-PWY |
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| purine nucleotides de novo biosynthesis I Accession ID: BioCyc:TRYPANO_DENOVOPURINE2-PWY |
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| tetrahydrofolate biosynthesis I Accession ID: BioCyc:TRYPANO_PWY-3742 |
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| salvage pathways of purine nucleosides I Accession ID: BioCyc:TRYPANO_P121-PWY |
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| β-alanine biosynthesis II Accession ID: BioCyc:TRYPANO_PWY-3941 |
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| asparagine biosynthesis II Accession ID: BioCyc:TRYPANO_ASPARAGINESYN-PWY |
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| fatty acid oxidation pathway Accession ID: BioCyc:CALBI_YEAST-FAO-PWY |
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Hiltunen JK, Wenzel B, Beyer A, Erdmann R, Fosså A, Kunau WH. Peroxisomal multifunctional beta-oxidation protein of Saccharomyces cerevisiae. Molecular analysis of the fox2 gene and gene product. Journal of Biological Chemistry. 1992 Apr;267(10):6646–53. doi: 10.1016/s0021-9258(19)50476-8.; Small GM, Szabo LJ, Lazarow PB. Acyl-CoA oxidase contains two targeting sequences each of which can mediate protein import into peroxisomes. The EMBO Journal. 1988 Apr;7(4):1167–73. doi: 10.1002/j.1460-2075.1988.tb02927.x. |
| tRNA charging pathway Accession ID: BioCyc:CALBI_TRNA-CHARGING-PWY |
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Hasenoehrl A, Galic´ T, Ergovic´ G, Mars?ic´ N, Skerlev M, Mittendorf J, Geschke U, Schmidt A, Schoenfeld W. In Vitro Activity and In Vivo Efficacy of Icofungipen (PLD-118), a Novel Oral Antifungal Agent, against the Pathogenic Yeast Candida albicans. Antimicrob Agents Chemother. 2006 Sep;50(9):3011–8. doi: 10.1128/aac.00254-06.; Petraitiene R, Petraitis V, Kelaher AM, Sarafandi AA, Mickiene D, Groll AH, Sein T, Bacher J, Walsh TJ. Efficacy, Plasma Pharmacokinetics, and Safety of Icofungipen, an Inhibitor of Candida Isoleucyl-tRNA Synthetase, in Treatment of Experimental Disseminated Candidiasis in Persistently Neutropenic Rabbits. Antimicrob Agents Chemother. 2005 May;49(5):2084–92. doi: 10.1128/aac.49.5.2084-2092.2005.; Petraitis V, Petraitiene R, Kelaher AM, Sarafandi AA, Sein T, Mickiene D, Bacher J, Groll AH, Walsh TJ. Efficacy of PLD-118, a Novel Inhibitor of Candida Isoleucyl-tRNA Synthetase, against Experimental Oropharyngeal and Esophageal Candidiasis Caused by Fluconazole-Resistant C. albicans. Antimicrob Agents Chemother. 2004 Oct;48(10):3959–67. doi: 10.1128/aac.48.10.3959-3967.2004.; Mittendorf J, Kunisch F, Matzke M, Militzer HC, Schmidt A, Schönfeld W. Novel antifungal beta-amino acids: synthesis and activity against Candida albicans. Bioorg Med Chem Lett. 2003 Feb 10;13(3):433–6. doi: 10.1016/s0960-894x(02)00958-7. PMID: 12565945. |
| arginine biosynthesis Accession ID: BioCyc:CALBI_ARGSYNBSUB-PWY |
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