数据之源，洞见之始

Protein Function: hyoscyamine (6S)-dioxygenase / 6beta-hydroxyhyoscyamine epoxidase [EC:1.14.11.11 1.14.20.13]

DBLinks

• KEGG: K12692
• EC Number: 1.14.11.11
• EC Number: 1.14.20.13

Reactions

reaction id	name	note
KEGG:R03812	L-hyoscyamine,2-oxoglytarate:oxygen oxidoreductase ((6S)-hydroxylating)	L-Hyoscyamine + 2-Oxoglutarate + Oxygen <=> (6S)-Hydroxyhyoscyamine + Succinate + CO2
Rhea:RHEA:12630	L-hyoscyamine + 2-oxoglutarate + O2 => (6S)-6-hydroxyhyoscyamine + succinate + CO2
Rhea:RHEA:12631	(6S)-6-hydroxyhyoscyamine + succinate + CO2 => L-hyoscyamine + 2-oxoglutarate + O2
Rhea:RHEA:12632	L-hyoscyamine + 2-oxoglutarate + O2 <=> (6S)-6-hydroxyhyoscyamine + succinate + CO2
BioCyc:HYOSCYAMINE-6-DIOXYGENASE-RXN	L-HYOSCYAMINE + 2-KETOGLUTARATE + OXYGEN-MOLECULE --> CPD-2202 + SUC + CARBON-DIOXIDE
KEGG:R03737	(6S)-6beta-hydroxyhyoscyamine,2-oxoglutarate:oxygen oxidoreductase (epoxide-forming)	(6S)-Hydroxyhyoscyamine + 2-Oxoglutarate + Oxygen <=> Scopolamine + Succinate + CO2 + H2O
Rhea:RHEA:12798	(6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 => scopolamine + succinate + CO2 + H2O + H+	Published in: Hashimoto, T., Kohno, J. and Yamada, Y. 6beta-Hydroxyhyoscyamine epoxidase from cultured roots of Hyoscyamus niger. Phytochemistry 28 (1989) 1077–1082.
Rhea:RHEA:12799	scopolamine + succinate + CO2 + H2O + H+ => (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2	Published in: Hashimoto, T., Kohno, J. and Yamada, Y. 6beta-Hydroxyhyoscyamine epoxidase from cultured roots of Hyoscyamus niger. Phytochemistry 28 (1989) 1077–1082.
Rhea:RHEA:12800	(6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 <=> scopolamine + succinate + CO2 + H2O + H+	Published in: Hashimoto, T., Kohno, J. and Yamada, Y. 6beta-Hydroxyhyoscyamine epoxidase from cultured roots of Hyoscyamus niger. Phytochemistry 28 (1989) 1077–1082.
BioCyc:6-BETA-HYDROXYHYOSCYAMINE-EPOXIDASE-RXN	CPD-2202 + 2-KETOGLUTARATE + OXYGEN-MOLECULE --> PROTON + SCOPOLAMINE + SUC + CARBON-DIOXIDE + WATER