Pathways Knowlegdes

Biological pathway database


Pathway DOIs Note
Sphingolipid metabolism overview

Accession ID: WikiPathways:WP4725
  • 10.1074/jbc.m109968200
Le Stunff H, Peterson C, Thornton R, Milstien S, Mandala SM, Spiegel S. Characterization of Murine Sphingosine-1-phosphate Phosphohydrolase. Journal of Biological Chemistry. 2002 Mar;277(11):8920–7. doi: 10.1074/jbc.m109968200.
Sphingolipid pathway

Accession ID: WikiPathways:WP1422
  • 10.1194/jlr.r800073-jlr200
Merrill AH, Stokes TH, Momin A, Park H, Portz BJ, Kelly S, Wang E, Sullards MC, Wang MD. Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease. Journal of Lipid Research. 2009 Apr;50():S97–S102. doi: 10.1194/jlr.r800073-jlr200.
Biochemical pathways: part I

Accession ID: WikiPathways:WP3604
  • 10.1016/s0303-2647(98)00019-7
Michal G. On representation of metabolic pathways. Biosystems. 1998 Jun;47(1-2):1–7. doi: 10.1016/s0303-2647(98)00019-7. PMID: 9715748.
Sphingolipid metabolism (integrated pathway)

Accession ID: WikiPathways:WP4690
  • 10.1074/jbc.m110.182915
Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH, Sullards MC, Wang E, Murphy RC, Raetz CRH, Garrett TA, Guan Z, Ryan AC, Russell DW, McDonald JG, Thompson BM, Shaw WA, Sud M, Zhao Y, Gupta S, Maurya MR, Fahy E, Subramaniam S. A Mouse Macrophage Lipidome. Journal of Biological Chemistry. 2010 Dec;285(51):39976–85. doi: 10.1074/jbc.m110.182915.
Sphingolipid metabolism

Accession ID: WikiPathways:WP3232
  • 10.1016/j.tibs.2007.09.004
Merrill AH, Wang MD, Park M, Sullards MC. (Glyco)sphingolipidology: an amazing challenge and opportunity for systems biology. Trends Biochem Sci. 2007 Oct;32(10):457–68. doi: 10.1016/j.tibs.2007.09.004. PMID: 17928229.
Sphingolipid metabolism overview

Accession ID: WikiPathways:WP4344
  • 10.1074/jbc.r200009200
Merrill AH. De Novo Sphingolipid Biosynthesis: A Necessary, but Dangerous, Pathway. Journal of Biological Chemistry. 2002 Jul;277(29):25843–6. doi: 10.1074/jbc.r200009200.
SARS-CoV-2 and COVID-19 pathway

Accession ID: WikiPathways:WP4846
  • 10.1002/jmv.25754
Kandeel M, Ibrahim A, Fayez M, Al-Nazawi M. From SARS and MERS CoVs to SARS-CoV-2: Moving toward more biased codon usage in viral structural and nonstructural genes. Journal of Medical Virology. 2020 Mar 16;92(6):660–6. doi: 10.1002/jmv.25754.
Synthesis of ceramides and 1-deoxyceramides

Accession ID: WikiPathways:WP5194
  • 10.1111/apha.13635
Sen P, Hyötyläinen T, Orešic M. 1-Deoxyceramides - Key players in lipotoxicity and progression to type 2 diabetes? Acta Physiol (Oxf). 2021 May;232(1):e13635. doi: 10.1111/apha.13635. PMID: 33630410.
Sphingolipid metabolism: integrated pathway

Accession ID: WikiPathways:WP4726
  • 10.1042/bj20050291
Mizutani Y, Kihara A, Igarashi Y. Mammalian Lass6 and its related family members regulate synthesis of specific ceramides. Biochem J. 2005 Aug 15;390(Pt 1):263–71. PMID: 15823095; PMCID: PMC1184580.
GDNF signaling

Accession ID: WikiPathways:WP5143
  • 10.1016/s0896-6273(00)80318-9
Baloh RH, Tansey MG, Golden JP, Creedon DJ, Heuckeroth RO, Keck CL, Zimonjic DB, Popescu NC, Johnson EM, Milbrandt J. TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. Neuron. 1997 May;18(5):793–802. doi: 10.1016/s0896-6273(00)80318-9. PMID: 9182803.