Pathways Knowlegdes

Biological pathway database


Pathway DOIs Note
threonine degradation

Accession ID: BioCyc:CALBI_THREOCAT-PWY
  • 10.1093/genetics/131.3.531
Bornaes C, Petersen JG, Holmberg S. Serine and threonine catabolism in Saccharomyces cerevisiae: the CHA1 polypeptide is homologous with other serine and threonine dehydratases. Genetics. 1992 Jul;131(3):531–9. PMID: 1628804; PMCID: PMC1205027.
isoleucine biosynthesis

Accession ID: BioCyc:CALBI_ILEUSYN-PWY
  • 10.1007/bf00387766
  • 10.1128/ec.5.5.816-824.2006
  • 10.1128/jb.151.3.1247-1252.1982
Kingsbury JM, Goldstein AL, McCusker JH. Role of Nitrogen and Carbon Transport, Regulation, and Metabolism Genes for Saccharomyces cerevisiae Survival In Vivo. Eukaryot Cell. 2006 May;5(5):816–24. doi: 10.1128/ec.5.5.816-824.2006.; Holmberg S, Petersen JG. Regulation of isoleucine-valine biosynthesis in Saccharomyces cerevisiae. Curr Genet. 1988 Mar;13(3):207–17. doi: 10.1007/bf00387766. PMID: 3289762.; Kakar SN, Magee PT. Genetic analysis of Candida albicans: identification of different isoleucine-valine, methionine, and arginine alleles by complementation. J Bacteriol. 1982 Sep;151(3):1247–52. doi: 10.1128/jb.151.3.1247-1252.1982.; Szentirmai A, Horváth I. Regulation of branched-chain amino acid biosynthesis. Acta Microbiol Acad Sci Hung. 1976;23(2):137–49. PMID: 788468.
cysteine and homocysteine interconversion

Accession ID: BioCyc:CALBI_PWY-801
  • 10.1002/(sici)1097-0061(19990930)15:13<1365::aid-yea468>3.0.co;2-u
  • 10.1002/yea.1076
  • 10.1016/0003-9861(68)90164-1
  • 10.1111/j.1462-5822.2006.00761.x
  • 10.1128/.61.4.503-532.1997
  • 10.1128/ec.4.9.1562-1573.2005
  • 10.1139/m73-024
Nobile CJ, Mitchell AP. Genetics and genomics of Candida albicans biofilm formation. Cell Microbiol. 2006 Sep;8(9):1382–91. doi: 10.1111/j.1462-5822.2006.00761.x. PMID: 16848788.; Murillo LA, Newport G, Lan C, Habelitz S, Dungan J, Agabian NM. Genome-Wide Transcription Profiling of the Early Phase of Biofilm Formation by Candida albicans. Eukaryot Cell. 2005 Sep;4(9):1562–73. doi: 10.1128/ec.4.9.1562-1573.2005.; Mulet JM, Alemany B, Ros R, Calvete JJ, Serrano R. Expression of a plant serine O-acetyltransferase in Saccharomyces cerevisiae confers osmotic tolerance and creates an alternative pathway for cysteine biosynthesis. Yeast. 2004 Mar;21(4):303–12. doi: 10.1002/yea.1076. PMID: 15042590.; Ono BI, Hazu T, Yoshida S, Kawato T, Shinoda S, Brzvwczy J, Paszewski A. Cysteine biosynthesis in Saccharomyces cerevisiae: a new outlook on pathway and regulation. Yeast. 1999 Sep 30;15(13):1365–75. doi: 10.1002/(sici)1097-0061(19990930)15:13<1365::aid-yea468>3.0.co;2-u. PMID: 10509018.; Thomas D, Surdin-Kerjan Y. Metabolism of sulfur amino acids in Saccharomyces cerevisiae. Microbiol Mol Biol Rev. 1997 Dec;61(4):503–32. doi: 10.1128/mmbr.61.4.503-532.1997.; Morzycka E, Paszewski A. Cysteine and homocysteine synthesis in Saccharomycopsis lipolytica; identification and characterization of two cysteine synthases. Acta Biochim Pol. 1982;29(1-2):81–93. PMID: 7180327.; Paszewski A, Grabski J. On sulfhydrylation of O-acetylserine and O-acetylhomoserine in homocysteine synthesis in yeast. Acta Biochim Pol. 1976;23(4):321–4. PMID: 1015154.; Wain WH, Price MF, Cawson RA. A re-evaluation of the effect of cysteine or Candida albicans. Sabouraudia. 1975 Mar;13 Pt 1():74–82. PMID: 1092000.; Mardon DN. In vivo synthesis of sulfur containing amino acids in Candida albicans. Can J Microbiol. 1973 Feb;19(2):155–61. doi: 10.1139/m73-024. PMID: 4572423.; Schlenk F, Zydek CR. Observations on the metabolism of sulfur amino acid derivatives in yeast. Archives of Biochemistry and Biophysics. 1968 Mar;123(3):438–46. doi: 10.1016/0003-9861(68)90164-1.
superpathway of leucine, valine, and isoleucine biosynthesis

Accession ID: BioCyc:CALBI_BRANCHED-CHAIN-AA-SYN-PWY
  • 10.1128/mmbr.67.1.1-15.2003
Kohlhaw GB. Leucine biosynthesis in fungi: entering metabolism through the back door. Microbiol Mol Biol Rev. 2003 Mar;67(1):1–15, table of contents. PMID: 12626680; PMCID: PMC150519.
Isoleucine Biosynthesis

Accession ID: PathBank:SMP0000838
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Propanoate Metabolism

Accession ID: PathBank:SMP0000957
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Metabolism and regulation

Accession ID: Plant Reactome:R-OAU-2744345
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Amino acid metabolism

Accession ID: Plant Reactome:R-OAU-2744343
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Isoleucine biosynthesis from threonine

Accession ID: Plant Reactome:R-TAE-1119460
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Amino acid biosynthesis

Accession ID: Plant Reactome:R-FVE-5655122
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Metabolism and regulation

Accession ID: Plant Reactome:R-MES-2744345
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Amino acid metabolism

Accession ID: Plant Reactome:R-MES-2744343
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Metabolism and regulation

Accession ID: Plant Reactome:R-TDI-2744345
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Amino acid metabolism

Accession ID: Plant Reactome:R-TDI-2744343
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Metabolism and regulation

Accession ID: Plant Reactome:R-DRO-2744345
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Amino acid biosynthesis

Accession ID: Plant Reactome:R-DRO-5655122
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Isoleucine biosynthesis from threonine

Accession ID: Plant Reactome:R-DRO-1119460
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Amino acid biosynthesis

Accession ID: Plant Reactome:R-OMI-5655122
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Isoleucine biosynthesis from threonine

Accession ID: Plant Reactome:R-OMI-1119460
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Metabolism and regulation

Accession ID: Plant Reactome:R-PTI-2744345
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