Pathways Knowlegdes

Biological pathway database


Pathway DOIs Note
Fucose and Rhamnose Degradation

Accession ID: PathBank:SMP0000846
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L-Lactaldehyde Degradation (Aerobic)

Accession ID: PathBank:SMP0002085
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Methylglyoxal Degradation IV

Accession ID: PathBank:SMP0002090
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Methylglyoxal Degradation I

Accession ID: PathBank:SMP0002125
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Proton-coupled monocarboxylate transport

Accession ID: Reactome:R-CEL-433692
  • 10.1074/jbc.m411950200
  • 10.1208/s12248-008-9035-6
  • 10.14670/hh-24.243
Merezhinskaya N, Fishbein WN. Monocarboxylate transporters: past, present, and future. Histol Histopathol. 2009 Feb;24(2):243–64. doi: 10.14670/hh-24.243. PMID: 19085840.; Morris ME, Felmlee MA. Overview of the Proton-coupled MCT (SLC16A) Family of Transporters: Characterization, Function and Role in the Transport of the Drug of Abuse ?-Hydroxybutyric Acid. The AAPS Journal. 2008 Jun 04;10(2):311. doi: 10.1208/s12248-008-9035-6.; Wilson MC, Meredith D, Fox JE, Manoharan C, Davies AJ, Halestrap AP. Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70). J Biol Chem. 2005 Jul 22;280(29):27213–21. doi: 10.1074/jbc.m411950200. PMID: 15917240.
SLC-mediated transport of organic anions

Accession ID: Reactome:R-CEL-9955298
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SLC-mediated transport of organic anions

Accession ID: Reactome:R-CFA-9955298
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SLC-mediated transport of organic anions

Accession ID: Reactome:R-DRE-9955298
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SLC-mediated transport of organic anions

Accession ID: Reactome:R-SSC-9955298
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SLC-mediated transport of organic anions

Accession ID: Reactome:R-BTA-9955298
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SLC-mediated transport of organic anions

Accession ID: Reactome:R-XTR-9955298
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SLC-mediated transport of organic anions

Accession ID: Reactome:R-HSA-9955298
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SLC-mediated transport of organic anions

Accession ID: Reactome:R-DME-9955298
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SLC-mediated transport of organic anions

Accession ID: Reactome:R-GGA-9955298
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SLC-mediated transport of organic anions

Accession ID: Reactome:R-MMU-9955298
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SLC-mediated transport of organic anions

Accession ID: Reactome:R-RNO-9955298
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Hydroxycarboxylic acid-binding receptors

Accession ID: Reactome:R-DRE-3296197
  • 10.1124/pr.110.003301
Offermanns S, Colletti SL, Lovenberg TW, Semple G, Wise A, IJzerman AP. International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B). Pharmacol Rev. 2011 Jun;63(2):269–90. doi: 10.1124/pr.110.003301. PMID: 21454438.
Proton-coupled monocarboxylate transport

Accession ID: Reactome:R-DME-433692
  • 10.1074/jbc.m411950200
  • 10.1208/s12248-008-9035-6
  • 10.14670/hh-24.243
Merezhinskaya N, Fishbein WN. Monocarboxylate transporters: past, present, and future. Histol Histopathol. 2009 Feb;24(2):243–64. doi: 10.14670/hh-24.243. PMID: 19085840.; Morris ME, Felmlee MA. Overview of the Proton-coupled MCT (SLC16A) Family of Transporters: Characterization, Function and Role in the Transport of the Drug of Abuse ?-Hydroxybutyric Acid. The AAPS Journal. 2008 Jun 04;10(2):311. doi: 10.1208/s12248-008-9035-6.; Wilson MC, Meredith D, Fox JE, Manoharan C, Davies AJ, Halestrap AP. Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70). J Biol Chem. 2005 Jul 22;280(29):27213–21. doi: 10.1074/jbc.m411950200. PMID: 15917240.
Organic anion transport by SLC22 transporters

Accession ID: Reactome:R-CEL-561048
  • 10.1007/s00424-003-1089-9
  • 10.1007/s11095-006-9181-4
  • 10.1097/mnh.0b013e32830b5d5d
Ahn S, Bhatnagar V. Update on the molecular physiology of organic anion transporters. Current Opinion in Nephrology and Hypertension. 2008 Sep;17(5):499–505. doi: 10.1097/mnh.0b013e32830b5d5d.; Rizwan AN, Burckhardt G. Organic Anion Transporters of the SLC22 Family: Biopharmaceutical, Physiological, and Pathological Roles. Pharmaceutical Research. 2007 Jan 24;24(3):450–70. doi: 10.1007/s11095-006-9181-4.; Koepsell H, Endou H. The SLC22 drug transporter family. Pflügers Archiv - European Journal of Physiology. 2003 Jul 19;447(5):666–76. doi: 10.1007/s00424-003-1089-9.
GPCR ligand binding

Accession ID: Reactome:R-BTA-500792
  • 10.1016/j.pharmthera.2004.05.002
  • 10.1034/j.1600-0773.2002.910607.x
  • 10.1124/mol.63.6.1256
Kristiansen K. Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function. Pharmacol Ther. 2004 Jul;103(1):21–80. doi: 10.1016/j.pharmthera.2004.05.002. PMID: 15251227.; Fredriksson R, Lagerström MC, Lundin LG, Schiöth HB. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol. 2003 Jun;63(6):1256–72. doi: 10.1124/mol.63.6.1256. PMID: 12761335.; Gether U, Asmar F, Meinild AK, Rasmussen SG. Structural basis for activation of G-protein-coupled receptors. Pharmacol Toxicol. 2002 Dec;91(6):304–12. doi: 10.1034/j.1600-0773.2002.910607.x. PMID: 12688373.