L-methionine salvage cycle I (bacteria and plants)

Metabolites

5'-Methylthioadenosine

Formula: C11H15N5O3S (297.089556)

CAS ID: 2457-80-9

Adenine

Formula: C5H5N5 (135.054493)

CAS ID: 73-24-5

ADP

Formula: C10H15N5O10P2 (427.02941500000003)

CAS ID: 58-64-0

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

S-adenosyl-L-methioninamine

Formula: C14H24N6O3S (356.1630514)

CAS ID:

S-methyl-5-thioαD-ribose 1-phosphate(2-)

Formula: C6H11O7PS (257.9963106)

CAS ID:

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:



Enzyme

EC Number name full name note
2.5.1.6 methionine adenosyltransferase ATP:L-methionine S-adenosyltransferase
2.7.1.100 S-methyl-5-thioribose kinase ATP:S-methyl-5-thio-D-ribose 1-phosphotransferase
3.2.2.16 methylthioadenosine nucleosidase S-methyl-5'-thioadenosine adeninehyrolase
3.2.2.9 adenosylhomocysteine nucleosidase S-adenosyl-L-homocysteine homocysteinylribohydrolase
4.1.1.50 adenosylmethionine decarboxylase S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-salt-forming]


Pathway Source

Organism Taxonomy Group Enzyme List Source Ratio
Enterobacter sp. 638 bacteria 2.5.1.6 / 2.7.1.100 / 3.2.2.16 / 3.2.2.9 / 4.1.1.50 100.00%
Clostridium botulinum A str. ATCC 3502 MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.16 / 3.2.2.9 / 4.1.1.50 100.00%
Geobacillus kaustophilus HTA426 MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.16 / 3.2.2.9 / 4.1.1.50 100.00%
Bacillus cereus ATCC 14579 MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.16 / 3.2.2.9 / 4.1.1.50 100.00%
Bacillus subtilis subsp. subtilis str. 168 MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.16 / 3.2.2.9 / 4.1.1.50 100.00%
Clostridium tetani E88 MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.16 / 3.2.2.9 / 4.1.1.50 100.00%
Bacillus cereus E33L MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.9 / 4.1.1.50 80.00%
Oryza sativa plant 2.5.1.6 / 2.7.1.100 / 3.2.2.9 / 4.1.1.50 80.00%
Bacillus cereus ATCC 10987 MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.9 / 4.1.1.50 80.00%
Thermus thermophilus HB27 MAGs 2.5.1.6 / 3.2.2.16 / 3.2.2.9 / 4.1.1.50 80.00%
Thermotoga maritima MSB8 MAGs 2.5.1.6 / 3.2.2.16 / 3.2.2.9 / 4.1.1.50 80.00%
Bacillus licheniformis DSM 13 = ATCC 14580 MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.9 / 4.1.1.50 80.00%
Francisella tularensis subsp. tularensis MAGs 2.5.1.6 / 3.2.2.16 / 3.2.2.9 / 4.1.1.50 80.00%
Bacillus anthracis bacteria 2.5.1.6 / 2.7.1.100 / 3.2.2.9 / 4.1.1.50 80.00%
Citrobacter koseri ATCC BAA-895 MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.9 / 4.1.1.50 80.00%
Thermotoga neapolitana DSM 4359 MAGs 2.5.1.6 / 3.2.2.16 / 3.2.2.9 / 4.1.1.50 80.00%
Francisella tularensis subsp. tularensis SCHU S4 MAGs 2.5.1.6 / 3.2.2.16 / 3.2.2.9 / 4.1.1.50 80.00%
Cronobacter sakazakii ATCC BAA-894 MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.9 / 4.1.1.50 80.00%
Pectobacterium atrosepticum SCRI1043 MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.9 / 4.1.1.50 80.00%
Yersinia pseudotuberculosis IP 32953 MAGs 2.5.1.6 / 2.7.1.100 / 3.2.2.9 / 4.1.1.50 80.00%