Microbial Natural Product
Microbial natural products, primarily secondary metabolites produced by bacteria, fungi, and other microorganisms, remain a cornerstone of modern medicine and biotechnology. They form the foundation of numerous antibiotics (e.g., penicillin, streptomycin), anticancer agents, and immunosuppressants, addressing critical global health challenges like infectious diseases and cancer. Despite historical challenges such as compound rediscovery and complex biosynthesis, advances in genomics, metabolomics, and synthetic biology are unlocking novel chemical diversity from underexplored microbial sources. Consequently, microbial natural products continue to represent an unparalleled reservoir for discovering next-generation therapeutics, underscoring their enduring significance in drug development and sustainable bioprospecting. (98 words)
Nonaflavuxanthin
A C45 carotenoid that is an intermediate in the biosyntheses of decaprenoxanthin by Corynebacterium glutamicum and gamma-cyclic sarcinaxanthin by Micr...
Dehydrosoyasaponin I
Dehydrosoyasaponin I is found in common pea. Dehydrosoyasaponin I is a constituent of soya bean (Glycine max) and alfalfa (Medicago sativa).
2,4-dihydroxy-6-methylbenzoic acid ethyl ester
2,4-dihydroxy-6-methylbenzoic acid ethyl ester is a 4-hydroxybenzoate ester.
Triclosan
Formula: C12H7Cl3O2 (287.9512)
Triclosan is an antibacterial and antifungal agent. It is a polychloro phenoxy phenol. It is widely used as a preservative and antimicrobial agent in ...
Protodioscin
Formula: C51H84O22 (1048.5454)
Asparasaponin I is found in fenugreek. Asparasaponin I is a bitter principle from white asparagus shoots (Asparagus officinalis) and fenugreek (Trigon...
Araliasaponin V
Formula: C54H88O23 (1104.5716)
Calenduloside D is a constituent of the roots of Calendula officinalis (pot marigold).
2-Methylbenzothiazole
2-Methylbenzothiazole is found in tea. Known as an aroma constituent of tea leaves.
2-Mercaptobenzothiazole
2(3H)-Benzothiazolethione is found in fruits. 2(3H)-Benzothiazolethione is a constituent of cranberries
2-hydroxybenzothiazole
Benzothiazole substituted with a hydroxy group at the 2-position." []
4,4'-Diapophytofluene
An apo carotenoid triterpenoid that is tetracosane containing double bonds at the 2-3, 6-7, 8-9, 10-11, 12-13, 14-15, 18-19, and 22-23 positions, and ...
4,4'-Diapo-zeta-carotene
An apo carotenoid triterpenoid that is tetracosane containing double bonds at the 2-3, 6-7, 8-9, 10-11, 12-13, 14-15, 16-17, 18-19, and 22-23 position...
Glucosyl-4,4'-diaponeurosporenoate
beta-D-glucosyl 4,4'-diaponeurosporenoic acid
Staphyloxanthin
A xanthophyll that is beta-D-glucopyranose in which the hydroxy groups at positions 1 and 6 have been acylated by an all-trans-2,6,10,15,19,23-hexamet...
Staphylopine
Formula: C13H20N4O6 (328.1383)
bacillithiol
Formula: C13H22N2O10S (398.0995)
A thiol that is the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid." []
N-cis-Feruloyltyramine
N-cis-Feruloyltyramine is found in cherimoya. N-cis-Feruloyltyramine is isolated from bell pepper.
Caffeic acid ethyl ester
Caffeic acid ethyl ester, also known as (E)-ethyl 3,4-dihydroxycinnamate or (E)-ethyl caffeate, belongs to coumaric acids and derivatives class of com...
Ethyl 4-hydroxy-3-methoxycinnamate
2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester is a natural product found in Spiraea formosana, Solanum nigrum, and other organisms wit...
Methyl 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate
Methyl 4-hydroxy-3,5-dimethoxycinnamate; Sinapic acid methyl ester is a natural product found in Goniothalamus laoticus, Brassica carinata, and other ...
Solanidine
Solanidine is a steroidal alkaloid, and its glycosides have been reported to have caused poisoning in man and animals. Solanidine is present in sera o...
2-Methoxy-4-methylphenol
2-Methoxy-4-methylphenol, also known as 4-methylguaiacol or creosol, belongs to the class of organic compounds known as methoxyphenols. Methoxyphenols...
Physalin F
Physalin J is found in fruits. Physalin J is a constituent of the famine food Physalis angulata (cutleaf ground cherry)
Physalin G
Physalin G is found in fruits. Physalin G is a constituent of the famine food Physalis angulata (cutleaf ground cherry)
Phenylethyl alcohol
2-Phenylethanol, also known as benzeneethanol or benzyl carbinol, belongs to the class of organic compounds known as benzene and substituted derivativ...
2-Acetylthiophene
2-Acetylthiophene, also known as 2-acetothienone or thiophene,2-acetyl, belongs to the class of organic compounds known as aryl alkyl ketones. These a...
Ethyl linoleate
(9Z,12Z)-Ethyl octadeca-9,12-dienoate is a natural product found in Zea mays, Artemisia argyi, and other organisms with data available.
Enterodiol
Enterodiol is one of the most important lignan-type phytoestrogens identified in serum, urine, bile, and seminal fluids of humans and animals. Phytoes...
Lariciresinol
(+)-Lariciresinol belongs to the class of organic compounds known as 7,9'-epoxylignans. These are lignans that contain the 7,9'-epoxylignan skeleton, ...
Ethyl octadeca-9,12,15-trienoate
Ethyl linolenate is a clear colorless liquid. (NTP, 1992) Ethyl octadeca-9,12,15-trienoate is a natural product found in Mangifera indica and Bidens ...
Methylrosmarinic acid
Methylrosmarinic acid is found in herbs and spices. Methylrosmarinic acid is isolated from Salvia (sage) species.
alpha-Spinasterol
alpha-Spinasterol is found in alfalfa. alpha-Spinasterol is a constituent of spinach (Spinacia oleracea) leaves, cucumber (Cucumis sativus), alfalfa m...