AMP (BioCAD00000006515)
cellular cytoplasm cerebrospinal fluid (csf) saliva placenta plant natural products
Metabolite Card
Chinese Name: 5'-腺苷酸
Formula: C10H14N5O7P (347.0631)
SMILES:
NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1Synonyms [en]
5'-AMP; Adenosine monophosphate; adenosine 5'-monophosphate; adenylic acid; 5'-adenylic acid; AMP
Reviewed
Last reviewed on 2026-04-16.
Cite this Page
AMP. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/AMP
(retrieved
2026-08-20) (CAD Registry RN: BioCAD00000006515). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Adenosine monophosphate, also known as 5'-adenylic acid and abbreviated AMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside adenosine. AMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase adenine. AMP can be produced during ATP synthesis by the enzyme adenylate kinase. AMP has recently been approved as a 'Bitter Blocker' additive to foodstuffs. When AMP is added to bitter foods or foods with a bitter aftertaste it makes them seem 'sweeter'. This potentially makes lower calorie food products more palatable.
Entity Information
DBLinks
- CAS Registry Number: 61-19-8
- PubChem CID: 6083
- ChEBI: 16027
- HMDB: HMDB0000045
- LipidMaps:
- KEGG: C00020
- BioCyc: AMP
- NCBI MeSH: Adenosine Monophosphate
- Wikipedia: Adenylic_acid
Other DBLinks
- CAS Registry Number: 122768-03-0
- CAS Registry Number: 136920-07-5
- CAS Registry Number: 4578-31-8
- CAS Registry Number: 53624-78-5
- CAS Registry Number: 61-19-8
- CAS Registry Number: 67583-85-1
- CAS Registry Number: 82530-89-0
- PubChem: 224
- PubChem: 3322
- PubChem: 6083
- ChEBI: ChEBI:16027
- HMDB: HMDB0000045
- HMDB: HMDB00045
- KEGG: C00020
- BioCyc: AMP
- NCBI MeSH: Adenosine Monophosphate
- Wikipedia: Adenosine_monophosphate
- Wikipedia: Adenylic_acid
- DrugBank: DB00131
- RefMet: RM0138921
- MoNA: BAF_UVA_POS000125
- MoNA: BAF_UVA_POS000126
- MoNA: BAF_UVA_POS000327
- MoNA: CCMSLIB00000577973
- MoNA: CCMSLIB00005464523
- MoNA: CCMSLIB00005464534
- MoNA: CCMSLIB00005464535
- MoNA: CCMSLIB00005720410
- MoNA: CCMSLIB00005720711
- MoNA: EMBL-MCF_spec118071
- MoNA: EMBL-MCF_spec365472
- MoNA: EMBL-MCF_spec365483
- MoNA: EMBL-MCF_spec365562
- MoNA: EMBL-MCF_spec365576
- MoNA: EMBL-MCF_spec393971
- MoNA: EMBL-MCF_spec393977
- MoNA: EMBL-MCF_spec393985
- MoNA: EMBL-MCF_spec46589
- MoNA: EMBL_MCF_2_0_HRMS_Library000086
- MoNA: EMBL_MCF_2_0_HRMS_Library000330
- MoNA: FiehnHILIC000158
- MoNA: FiehnHILIC001046
- MoNA: HMDB0000045_c_ms_2234
- MoNA: HMDB0000045_c_ms_2236
- MoNA: KNA00197
- MoNA: KNA00199
- MoNA: KNA00447
- MoNA: KNA00448
- MoNA: KNA00449
- MoNA: KNA00450
- MoNA: KNA00596
- MoNA: KNA00597
- MoNA: KNA00599
- MoNA: KNA00816
- MoNA: KNA00817
- MoNA: KNA00818
- MoNA: KNA00819
- MoNA: MoNA001866
- MoNA: MoNA001867
- MoNA: MoNA001869
- MoNA: MoNA010890
- MoNA: MoNA010891
- MoNA: MoNA010892
- MoNA: MoNA010893
- MoNA: MoNA016661
- MoNA: MoNA024217
- MoNA: MoNA024222
- MoNA: MoNA033888
- MoNA: MoNA033889
- MoNA: MoNA033891
- MoNA: MoNA035936
- MoNA: MoNA035939
- MoNA: MoNA035941
- MoNA: MoNA037818
- MoNA: MoNA038523
- MoNA: PM018195
- MoNA: PR100064
- MoNA: PR100065
- MoNA: PR100515
- MoNA: PS011001
- MoNA: PS011002
- MoNA: PS011003
- MoNA: PS011004
- MoNA: PS011005
- MoNA: PS011006
- MoNA: PS011007
- MoNA: PS011008
- MoNA: PS011009
- MoNA: PS011010
- MoNA: PS011011
- MoNA: PS075303
- MoNA: VF-NPL-LTQ000103
- MoNA: VF-NPL-LTQ000104
- MoNA: VF-NPL-LTQ000105
- MoNA: VF-NPL-LTQ000106
- MoNA: VF-NPL-QTOF006513
- MoNA: VF-NPL-QTOF006514
- MoNA: VF-NPL-QTOF006515
- MoNA: VF-NPL-QTOF006516
- MoNA: VF-NPL-QTOF006517
- MoNA: VF-NPL-QTOF006518
- MoNA: VF-NPL-QTOF006519
- MoNA: VF-NPL-QTOF006520
- MoNA: VF-NPL-QTOF006521
- Metlin: METLIN_34478
- Coconut NaturalProduct: CNP0216781.2
- Coconut NaturalProduct: CNP0216781.9
- PMHub: MS000000224
- metaboanalyst: 026c350b7d658f57c54f75db136d721a
- metaboanalyst: 5804d83b2ea7fb439d0fb6210edfdccc
- metaboanalyst: 7797b5cdecfd84422e9db56c0d0fc63d
- metaboanalyst: 9972864abc99511d52a4c4037779d287
- metaboanalyst: cf06de1426ee1c8bed2e713a526e6921
- HERB: HBIN011366
- HERB: HBIN048046
Class / Ontology
- WishartLab ClassyFire: [Purine ribonucleotides] Purine ribonucleotides
- RefMet: [Purine rNMP] Purine rNMP
- ChEBI: [CHEBI:16027] adenosine 5'-monophosphate
- Coconut NaturalProduct: [Purine nucleos(t)ides] Purine nucleos(t)ides
Metabolic Network
| ID | EC Number | Name |
|---|---|---|
| KEGG:R00085 | 3.6.1.5 | ATP diphosphohydrolase (phosphate-forming) |
| KEGG:R00087 | 3.6.1.8 | ATP diphosphohydrolase (diphosphate-forming); |
| KEGG:R00103 | 3.6.1.9 | NAD+ phosphohydrolase |
| KEGG:R00122 | 3.6.1.5 | ADP phosphohydrolase |
| KEGG:R00127 | 2.7.4.3 | ATP:AMP phosphotransferase |
| KEGG:R00157 | 2.7.4.10 | uridine triphosphate:AMP phosphotransferase; |
| KEGG:R00160 | 3.6.1.9 | FAD nucleotidohydrolase |
| KEGG:R00181 | 3.5.4.6 | AMP aminohydrolase |
| KEGG:R00182 | 3.2.2.4 | AMP phosphoribohydrolase |
| KEGG:R00183 | 3.1.3.5 | adenosine 5'-monophosphate phosphohydrolase |
| KEGG:R00184 | 3.6.1.17 | P1,P4-bis(5'-adenosyl)-tetraphosphate adenylohydrolase |
| KEGG:R00185 | 2.7.1.20 | ATP:adenosine 5'-phosphotransferase |
| KEGG:R00187 | 3.6.1.29 | P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase |
| KEGG:R00188 | 3.1.3.7 | adenosine-3',5'-bisphosphate 3'-phosphohydrolase |
| KEGG:R00189 | 6.3.1.5 | deamido-NAD+:ammonia ligase (AMP-forming) |
| KEGG:R00190 | 2.4.2.7 | AMP:diphosphate phospho-D-ribosyltransferase |
| KEGG:R00191 | 3.1.4.17 | adenosine 3',5'-phosphate 5'-nucleotidohydrolase |
| KEGG:R00199 | 2.7.9.2 | ATP:pyruvate,water phosphotransferase |
| KEGG:R00206 | 2.7.9.1 | ATP:pyruvate,phosphate phosphotransferase |
| KEGG:R00235 | 6.2.1.1 | acetate:CoA ligase (AMP-forming) |
Mass Spectrum
Organism Source
Taxonomy Source
- Agaricus campestris [ncbi taxid: 56157]
- Chlamydomonas reinhardtii [ncbi taxid: 3055]
- Escherichia coli [ncbi taxid: 562]
- Homo sapiens [ncbi taxid: 9606]
- Isodon rubescens [ncbi taxid: 587669]
- Mus musculus [ncbi taxid: 10090]
- Ophiocordyceps sinensis [ncbi taxid: 72228]
- Saccharomyces cerevisiae [ncbi taxid: 4932]
Pathway Synthetic
| pathway id | name |
|---|---|
| BioCyc:LEISH_PWY3IU-99 | superpathway of central carbon metabolism |
| BioCyc:LEISH_GLYCOLYSIS | glycolysis I |
| BioCyc:LEISH_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:LEISH_PWY-5381 | pyridine nucleotide cycling (plants) |
| BioCyc:LEISH_PWY3IU-445 | purine nucleotide metabolism (phosphotransfer and nucleotide modification) |
| BioCyc:LEISH_PWY0-901 | selenocysteine biosynthesis I (bacteria) |
| BioCyc:TRYPANO_PWY0-1313 | acetate conversion to acetyl-CoA |
| BioCyc:TRYPANO_PWY-1341 | phenylacetate degradation II (anaerobic) |
| BioCyc:TRYPANO_PWY-561 | superpathway of glyoxylate cycle |
| BioCyc:TRYPANO_GLYCOLYSIS-TCA-GLYOX-BYPASS | superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass |
| BioCyc:TRYPANO_P1-PWY | purine and pyrimidine metabolism |
| BioCyc:TRYPANO_PWY0-781 | aspartate superpathway |
| BioCyc:TRYPANO_PRPP-PWY | superpathway of histidine, purine, and pyrimidine biosynthesis |
| BioCyc:TRYPANO_PWY-6125 | guanosine nucleotides de novo biosynthesis |
| BioCyc:TRYPANO_PWY-5653 | NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde |
| BioCyc:TRYPANO_PWY0-662 | PRPP biosynthesis I |
| BioCyc:CALBI_PWY0-901 | selenocysteine biosynthesis |
| BioCyc:CALBI_PRPP-PWY | superpathway of histidine, purine and pyrimidine biosynthesis |
| BioCyc:CALBI_PWY-3742 | tetrahydrofolate biosynthesis |
| BioCyc:CALBI_PWY0-662 | PRPP biosynthesis |