EC: 1.1.1.399

2-oxoglutarate reductase ((R)-2-hydroxyglutarate,NAD+ 2-oxidireductase)

enzyme lambda metabolic reaction experiment
uniprot:O43175 [2-oxoglutarate reductase(Enzyme) wildtype His-tagged]

2_Oxoglutarate + H+ + NADH -> NAD+ + (R)_2_Hydroxyglutarate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 200 mM Tris
PH: 7.6
Temperature: 37
uniprot:O43175 [2-oxoglutarate reductase(Enzyme) wildtype His-tagged]

NADH + 2_Oxoglutarate + H+ -> (R)_2_Hydroxyglutarate + NAD+		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 200 mM Tris
PH: 7.6
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_SERSYN-PWY serine biosynthesis (phosphorylated route)
BioCyc:META_SULFATE-CYS-PWY superpathway of sulfate assimilation and cysteine biosynthesis
BioCyc:META_SER-GLYSYN-PWY superpathway of L-serine and glycine biosynthesis I
BioCyc:ECO_SERSYN-PWY L-serine biosynthesis I
BioCyc:MTBH37RV_SULFATE-CYS-PWY superpathway of sulfate assimilation and cysteine biosynthesis
BioCyc:ECOL316407_SULFATE-CYS-PWY superpathway of sulfate assimilation and cysteine biosynthesis
BioCyc:META_SERSYN-PWY L-serine biosynthesis I
BioCyc:YEAST_SER-GLYSYN-PWY superpathway of serine and glycine biosynthesis I
BioCyc:MTBH37RV_SERSYN-PWY L-serine biosynthesis I
BioCyc:MTBCDC1551_SULFATE-CYS-PWY superpathway of sulfate assimilation and cysteine biosynthesis
BioCyc:MTBCDC1551_SER-GLYSYN-PWY superpathway of L-serine and glycine biosynthesis I
BioCyc:MTBCDC1551_SERSYN-PWY L-serine biosynthesis
BioCyc:BSUB_SER-GLYSYN-PWY superpathway of L-serine and glycine biosynthesis I
BioCyc:ECO_SULFATE-CYS-PWY superpathway of sulfate assimilation and cysteine biosynthesis
BioCyc:ECO_SER-GLYSYN-PWY superpathway of L-serine and glycine biosynthesis I
BioCyc:ECOO157_SULFATE-CYS-PWY superpathway of sulfate assimilation and cysteine biosynthesis
BioCyc:ECOO157_SER-GLYSYN-PWY superpathway of serine and glycine biosynthesis I
BioCyc:BSUB_SULFATE-CYS-PWY superpathway of sulfate assimilation and cysteine biosynthesis
BioCyc:BSUB_SERSYN-PWY L-serine biosynthesis I
BioCyc:HUMAN_SER-GLYSYN-PWY serine and glycine biosynthesis
BioCyc:YEAST_SERSYN-PWY serine biosynthesis from 3-phosphoglycerate
BioCyc:MTBH37RV_SER-GLYSYN-PWY superpathway of L-serine and glycine biosynthesis I
BioCyc:ECOO157_SERSYN-PWY serine biosynthesis
BioCyc:ECOL199310_SULFATE-CYS-PWY superpathway of sulfate assimilation and cysteine biosynthesis
BioCyc:ECOL199310_SER-GLYSYN-PWY superpathway of serine and glycine biosynthesis I
BioCyc:ECOL199310_SERSYN-PWY serine biosynthesis
BioCyc:ECOL316407_SERSYN-PWY serine biosynthesis
BioCyc:ECOL316407_SER-GLYSYN-PWY superpathway of serine and glycine biosynthesis I
PathBank:SMP0000821 Cysteine Biosynthesis
PathBank:SMP0000829 Serine Biosynthesis and Metabolism
PathBank:SMP0000993 Secondary Metabolites: Cysteine Biosynthesis from Serine
Reactome:R-HSA-977347 Serine metabolism
Reactome:R-SSC-1430728 Metabolism
Reactome:R-SSC-977347 Serine metabolism
Reactome:R-HSA-71291 Amino acid and derivative metabolism
Reactome:R-SSC-71291 Amino acid and derivative metabolism
Reactome:R-HSA-1430728 Metabolism
WikiPathways:WP4688 Serine metabolism
WikiPathways:WP5355 Metabolic Epileptic Disorders
WikiPathways:WP5312 Metabolic pathways of fibroblasts
PathBank:SMP0000242 Dimethylglycine Dehydrogenase Deficiency
PathBank:SMP0000223 Non-Ketotic Hyperglycinemia
PathBank:SMP0000484 Dimethylglycine Dehydrogenase Deficiency
PathBank:SMP0000004 Glycine and Serine Metabolism
PathBank:SMP0000721 3-Phosphoglycerate Dehydrogenase Deficiency
PathBank:SMP0002323 Serine Metabolism
PathBank:SMP0000179 Dihydropyrimidine Dehydrogenase Deficiency (DHPD)
PathBank:SMP0000485 Hyperglycinemia, Non-Ketotic
PathBank:SMP0002320 Glycine Metabolism
PathBank:SMP0000244 Sarcosinemia