(-)-5-Oxo-1,2-campholide

Abstract: (-)-5-Oxo-1,2-campholide, a structurally modified camphor derivative, exhibits potential biological activities rooted in its unique oxo-functionalized structure. Preliminary evidence suggests it may possess anti-inflammatory properties, potentially through modulation of pro-inflammatory pathways (e.g., COX-2 inhibition), akin to related camphor derivatives. Its antimicrobial activity could arise from membrane-disrupting effects, common to terpenoid compounds. Additionally, the compound may interact with neuropharmacological targets, such as GABA receptors, hinting at possible anxiolytic or anticonvulsant effects. However, its specific mechanisms, efficacy, and safety profile remain under investigation, necessitating further studies to validate these hypotheses and explore therapeutic applications.

ID EC Number Name
KEGG:R12149 1.14.14.155 (-)-bornane-2,5-dione,FMNH2:oxygen oxidoreductase (1,2-lactonizing)
KEGG:R13091 C21930<=>C20271
BioCyc:RXN-13043 1.14.14.155 CPD-14061 + FMNH2 + OXYGEN-MOLECULE --> --5-oxo-1-2-campholide + WATER + FMN + PROTON
BioCyc:RXN-13044 --5-oxo-1-2-campholide --> CPD-866 + PROTON