BioCyc:RXN-16016
This is a hypothetical reaction. No information about the exact order of events leading to the biosynthesis of |FRAME: ARACHIDONIC_ACID| by the polyketide synthase complex is available at this time |CITS: [25263707]|.
ACETYL-COA + 9 MALONYL-COA + 14 NADPH + 22 PROTON --> ARACHIDONIC_ACID + 9 CARBON-DIOXIDE + 10 CO-A + 8 WATER + 14 NADP
Acetyl CoA[C23H38N7O17P3S] + 9 Malonyl-CoA[C24H38N7O19P3S] + 14 NADPH[C21H30N7O17P3] + 22 H+[H] = Arachidonate[C20H32O2] + 9 CO2[CO2] + 10 CoA[C21H36N7O16P3S] + 8 H2O[H2O] + 14 NADP[C21H28N7O17P3]
DB Links
- BioCyc: RXN-16016
- EC Number: 2.3.1.-
Alias
Metabolites
Substrates
| metabolite | compartment | Structure |
|---|---|---|
| Acetyl CoA Formula: C23H38N7O17P3S |
Cytoplasm | |
| Malonyl-CoA Formula: C24H38N7O19P3S |
Cytoplasm | |
| NADPH Formula: C21H30N7O17P3 |
Cytoplasm | |
| H+ Formula: H |
Cytoplasm |
Products
| metabolite | compartment | Structure |
|---|---|---|
| Arachidonate Formula: C20H32O2 |
Cytoplasm | |
| CO2 Formula: CO2 |
Cytoplasm | |
| CoA Formula: C21H36N7O16P3S |
Cytoplasm | |
| H2O Formula: H2O |
Cytoplasm | |
| NADP Formula: C21H28N7O17P3 |
Cytoplasm |