数据之源，洞见之始

(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O₂ <=> 3-hydroxy-L-phenylalanine + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin

Tetrahydrobiopterin[C9H15N5O3] + L-phenylalanine zwitterion[C9H11NO2] + Oxygen[O2] = Meta-Tyrosine[C9H11NO3] + 4a-Hydroxytetrahydrobiopterin[C9H15N5O4]

DB Links

• KEGG: R10729
• EC Number: 1.14.16.7
• Rhea: RHEA:41535

Alias

• [Rhea:RHEA:41533] (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O₂ => 3-hydroxy-L-phenylalanine + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin
• [Rhea:RHEA:41534] 3-hydroxy-L-phenylalanine + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O₂
• [Rhea:RHEA:41535] (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O₂ <=> 3-hydroxy-L-phenylalanine + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin

Metabolites

Substrates

metabolite	compartment	Structure
Tetrahydrobiopterin Formula: C9H15N5O3	Cytoplasm
L-phenylalanine zwitterion Formula: C9H11NO2	Cytoplasm
Oxygen Formula: O2	Cytoplasm

Products

metabolite	compartment	Structure
Meta-Tyrosine Formula: C9H11NO3	Cytoplasm
4a-Hydroxytetrahydrobiopterin Formula: C9H15N5O4	Cytoplasm