BioCyc:GLUTAMATESYN-RXN

The reaction is reductive amination of 2-oxoglutarate. Itcatalyzes the utilization of the amide nitrogen of glutamine in biosynthesis.

PROTON + GLN + 2-KETOGLUTARATE + NADPH --> 2 GLT + NADP

2 L-Glutamate[C5H9NO4] + NADP[C21H28N7O17P3] = H+[H] + L-Glutamine[C5H10N2O3] + 2-Oxoglutarate[C5H6O5] + NADPH[C21H30N7O17P3]

DB Links

  • BioCyc: GLUTAMATESYN-RXN
  • EC Number: 1.4.1.13
Alias

Metabolites

Substrates
metabolite compartment Structure
L-Glutamate

Formula: C5H9NO4 		Cytoplasm
NADP

Formula: C21H28N7O17P3 		Cytoplasm
Products
metabolite compartment Structure
H+

Formula: H		 Cytoplasm
L-Glutamine

Formula: C5H10N2O3		 Cytoplasm
2-Oxoglutarate

Formula: C5H6O5		 Cytoplasm
NADPH

Formula: C21H30N7O17P3		 Cytoplasm