Mitochondrion nucleoid

The mitochondrial nucleoid is the specialized, non-membrane-bound region within the mitochondrial matrix where mitochondrial DNA (mtDNA) is organized and maintained. It associates mtDNA with proteins (e.g., TFAM) to facilitate replication, transcription, and segregation, ensuring proper mitochondrial genome function and inheritance—distinct from nuclear genomic organization.

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Protein List

ID name Taxonomy Function
P20967 KGD1 Saccharomyces cerevisiae S288C 2-oxoglutarate dehydrogenase, mitochondrial
P20967 KGD1 Saccharomyces cerevisiae S288C 2-oxoglutarate dehydrogenase, mitochondrial
O76031 CLPX Homo sapiens ATP-dependent clpX-like chaperone, mitochondrial
O76031 CLPX Homo sapiens ATP-dependent clpX-like chaperone, mitochondrial
P29372 MPG Homo sapiens DNA-3-methyladenine glycosylase
P29372 MPG Homo sapiens DNA-3-methyladenine glycosylase
P34897 SHMT2 Homo sapiens Serine hydroxymethyltransferase, mitochondrial
P34897 SHMT2 Homo sapiens Serine hydroxymethyltransferase, mitochondrial
P54098 POLG Homo sapiens DNA polymerase subunit gamma-1
P54098 POLG Homo sapiens DNA polymerase subunit gamma-1
Q00059 TFAM Homo sapiens Transcription factor A, mitochondrial
Q00059 TFAM Homo sapiens Transcription factor A, mitochondrial
Q04837 SSBP1 Homo sapiens Single-stranded DNA-binding protein, mitochondrial
Q04837 SSBP1 Homo sapiens Single-stranded DNA-binding protein, mitochondrial
Q49AM1 MTERF2 Homo sapiens Transcription termination factor 2, mitochondrial
Q49AM1 MTERF2 Homo sapiens Transcription termination factor 2, mitochondrial
Q7L0Y3 TRMT10C Homo sapiens tRNA methyltransferase 10 homolog C
Q7L0Y3 TRMT10C Homo sapiens tRNA methyltransferase 10 homolog C
Q7L2E3 DHX30 Homo sapiens ATP-dependent RNA helicase DHX30
Q7L2E3 DHX30 Homo sapiens ATP-dependent RNA helicase DHX30
Q7L8L6 FASTKD5 Homo sapiens FAST kinase domain-containing protein 5, mitochondrial
Q7L8L6 FASTKD5 Homo sapiens FAST kinase domain-containing protein 5, mitochondrial
Q8IYB8 SUPV3L1 Homo sapiens ATP-dependent RNA helicase SUPV3L1, mitochondrial
Q8IYB8 SUPV3L1 Homo sapiens ATP-dependent RNA helicase SUPV3L1, mitochondrial
Q96QE5 TEFM Homo sapiens Transcription elongation factor, mitochondrial
Q96QE5 TEFM Homo sapiens Transcription elongation factor, mitochondrial
Q96RR1 TWNK Homo sapiens Twinkle mtDNA helicase
Q96RR1 TWNK Homo sapiens Twinkle mtDNA helicase
Q99714 HSD17B10 Homo sapiens 3-hydroxyacyl-CoA dehydrogenase type-2
Q99714 HSD17B10 Homo sapiens 3-hydroxyacyl-CoA dehydrogenase type-2
Q9BQ52 ELAC2 Homo sapiens Zinc phosphodiesterase ELAC protein 2
Q9BQ52 ELAC2 Homo sapiens Zinc phosphodiesterase ELAC protein 2
Q9BRT2 UQCC2 Homo sapiens Ubiquinol-cytochrome c reductase complex assembly factor 2
Q9BRT2 UQCC2 Homo sapiens Ubiquinol-cytochrome c reductase complex assembly factor 2
Q9BSJ5 MTNAP1 Homo sapiens Mitochondrial nucleoid-associated protein 1