NS5
K25332 NS5; Flavivirus RNA-directed RNA polymerase NS5 [EC:2.1.1.56. 2.1.1.57 2.7.7.48]
Protein Function: Flavivirus RNA-directed RNA polymerase NS5 [EC:2.1.1.56. 2.1.1.57 2.7.7.48]
DBLinks
Proteins
| protein id | name | function | taxonomy source |
|---|
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R03922 | S-adenosyl-L-methionine:5-(N7-methyl 5-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA] 2-O-methyltransferase | S-Adenosyl-L-methionine + m7G(5')pppR-mRNA <=> S-Adenosyl-L-homocysteine + m7G(5')pppRm-mRNA |
| Rhea:RHEA:67021 | a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine => a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA + S-adenosyl-L-homocysteine + H+ | |
| Rhea:RHEA:67022 | a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA + S-adenosyl-L-homocysteine + H+ => a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine | |
| Rhea:RHEA:67023 | a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA + S-adenosyl-L-homocysteine + H+ | |
| BioCyc:2.1.1.57-RXN | S-ADENOSYLMETHIONINE + m7G5-pppR-mRNAs --> m7G5-pppRm-mRNAs + ADENOSYL-HOMO-CYS + PROTON | |
| KEGG:R00435 | ATP:polynucleotide adenylyltransferase; | DNA-directed (ec 2.7.7.6) |
| KEGG:R00441 | GTP:RNA guanylyltransferase (DNA-directed); | DNA-directed (ec 2.7.7.6) |
| KEGG:R00442 | CTP:RNA cytidylyltransferase (DNA-directed); | DNA-directed (ec 2.7.7.6) |
| KEGG:R00443 | UTP:RNA uridylyltransferase | DNA-directed (ec 2.7.7.6) |
| KEGG:R00444 | nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed); | DNA-directed (ec 2.7.7.6) |