bioD
K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]
Protein Function: dethiobiotin synthetase [EC:6.3.3.3]
DBLinks
Proteins
| protein id | name | function | taxonomy source |
|---|---|---|---|
| A0A0F4Z225 | A0A0F4Z225_RASE3 | biotin synthase | Rasamsonia emersonii CBS 393.64 |
| A0AAD9GLM1 | A0AAD9GLM1_9STRA | Bifunctional dethiobiotin synthetase/7 | Phytophthora citrophthora |
| A0ACC6UHG8 | A0ACC6UHG8_STRAO | Dethiobiotin synthetase | Streptomyces albogriseolus |
| A8924_1371 | A8924_1371 | dethiobiotin synthetase | Saccharopolyspora erythraea NRRL 2338 |
| A9P79_12460 | A9P79_12460 | dethiobiotin synthase | Cupriavidus taiwanensis |
| AB57_0861 | AB57_0861 | dethiobiotin synthase | Acinetobacter baumannii AB0057 |
| ABW22_04430 | ABW22_04430 | dethiobiotin synthetase | Thiobacillus denitrificans |
| Acel_1052 | Acel_1052 | dethiobiotin synthase | Acidothermus cellulolyticus 11B |
| Amir_5739 | Amir_5739 | dethiobiotin synthase | Actinosynnema mirum DSM 43827 |
| AOY38_13705 | AOY38_13705 | dethiobiotin synthetase | Synechocystis sp. PCC 6803 |
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R03182 | 7,8-diaminononanoate:carbon-dioxide cyclo-ligase | two-step reaction (see R12933+R12934) |
| KEGG:R12933 | C01037 + C00011<=>C22458 | the first step of two-step reaction (see R03182, R12933+R12934) |
| KEGG:R12934 | C22458 + C00002<=>C01909 + C00008 + C00009 | the second step of two-step reaction (see R03182, R12933+R12934) |
| BioCyc:DETHIOBIOTIN-SYN-RXN | CARBON-DIOXIDE + DIAMINONONANOATE + ATP --> 3 PROTON + DETHIOBIOTIN + Pi + ADP | The third step in the biosynthesis of biotin. |
| Rhea:RHEA:15806 | (7R,8S)-7,8-diammoniononanoate + CO2 + ATP => (4R,5S)-dethiobiotin + ADP + phosphate + 3 H+ | Multi-step reaction: RHEA:63680 and RHEA:63684 |
| Rhea:RHEA:15807 | (4R,5S)-dethiobiotin + ADP + phosphate + 3 H+ => (7R,8S)-7,8-diammoniononanoate + CO2 + ATP | Multi-step reaction: RHEA:63680 and RHEA:63684 |
| Rhea:RHEA:15808 | (7R,8S)-7,8-diammoniononanoate + CO2 + ATP <=> (4R,5S)-dethiobiotin + ADP + phosphate + 3 H+ | Multi-step reaction: RHEA:63680 and RHEA:63684 |