CYP3A
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
Protein Function: cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
DBLinks
Proteins
| protein id | name | function | taxonomy source |
|---|---|---|---|
| Q6LEQ2 | Cyp3a23-3a1 | Cytochrome P450 3A | Rattus norvegicus |
| O09158 | Cyp3a25 | Cytochrome P450 3A25 | Mus musculus |
| Q9QXK4 | Cyp3a25 | Cytochrome P450 3A | Mus musculus |
| A0A494C0W7 | CYP3A4 | Cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| P08684 | CYP3A4 | Cytochrome P450 3A4 | Homo sapiens |
| Q6GRK0 | CYP3A4 | Cytochrome P450 3A | Homo sapiens |
| A0A499FJM4 | CYP3A4 | Cytochrome P450 3A | Homo sapiens |
| Q7Z448 | CYP3A4 | Cytochrome P450 3A | Homo sapiens |
| Q9JMA7 | Cyp3a41a | Cytochrome P450 3A41 | Mus musculus |
| Q9HB55 | CYP3A43 | Cytochrome P450 3A43 | Homo sapiens |
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R01842 | androstenedione,NADPH---hemoprotein reductase:oxygen oxidoreductase (7alpha-hydroxylating) | CYP2A1 |
| KEGG:R02354 | C00468 + C00080 + C00007 + C00004<=>C05298 + C00003 + C00001 | NADPH (see R02355) |
| KEGG:R02355 | C00468 + C00080 + C00007 + C00005<=>C05298 + C00006 + C00001 | NADH (see R02354) |
| KEGG:R02356 | C00468 + C00080 + C00007 + C00005<=>C05300 + C00006 + C00001 | Estrone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxyestrone + NADP+ + H2O |
| KEGG:R02503 | testosterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (7alpha-hydroxylating) | Testosterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7alpha-Hydroxytestosterone + [Oxidized NADPH---hemoprotein reductase] + H2O |
| KEGG:R03088 | C00951 + C00080 + C00007 + C00004<=>C05301 + C00003 + C00001 | Estradiol-17beta + H+ + Oxygen + NADH <=> 2-Hydroxyestradiol + NAD+ + H2O |
| KEGG:R03089 | C00951 + C00080 + C00007 + C00005<=>C05141 + C00006 + C00001 | Estradiol-17beta + H+ + Oxygen + NADPH <=> Estriol + NADP+ + H2O |
| KEGG:R03090 | C00951 + C00080 + C00007 + C00005<=>C05301 + C00006 + C00001 | Estradiol-17beta + H+ + Oxygen + NADPH <=> 2-Hydroxyestradiol + NADP+ + H2O |
| KEGG:R03408 | C01227 + C00080 + C00007 + C00005<=>C05139 + C00006 + C00001 | steroid 16alpha-hydroxylase |
| KEGG:R03629 | melatonin,NADPH---hemoprotein reductase:oxygen oxidoreductase | see R04122 |