ASTL

K08778 ASTL; astacin-like metalloendopeptidase [EC:3.4.-.-]

Protein Function: astacin-like metalloendopeptidase [EC:3.4.-.-]

DBLinks
Proteins
protein id name function taxonomy source
Q3B826 ASTL Metalloendopeptidase Homo sapiens
A2ARG6 Astl Metalloendopeptidase Mus musculus
D3ZX09 Astl Metalloendopeptidase Rattus norvegicus
A6HQ13 Astl Metalloendopeptidase Rattus norvegicus
Q6HA08 ASTL Astacin-like metalloendopeptidase Homo sapiens
Q6HA09 Astl Astacin-like metalloendopeptidase Mus musculus
Reactions
reaction id name note
KEGG:R04313 C03793 + 2 C00017<=>C05546 + 2 C00001 multi-step reaction
KEGG:R04869 C05552 + 2 C00012<=>C06250 + 2 C00001 Biocytin + 2 Peptide <=> Holo-[carboxylase] + 2 H2O
KEGG:R10891 C20917 + C00001<=>C20918 + C00188 putative tabtoxin peptidase
BioCyc:RXN-22576 CPD-24805 + WATER --> A-PEPTIDOGLYCAN-MDAP-TRIPEPTIDE + GLY
BioCyc:RXN0-5407 CPD0-1185 + WATER --> A-PEPTIDOGLYCAN-MDAP-TRIPEPTIDE + CPD-24859 This reaction represents hydrolysis of meso-DAP-meso-DAP (3 → 3) cross-links in peptidoglycan (see |CITS: [23066944]| for nomenclature of endopeptidase activity in E. coli K-12).
BioCyc:RXN-22575 CPD0-1171 + WATER --> a-murein-lipoprotein + A-PEPTIDOGLYCAN-MDAP-TRIPEPTIDE
BioCyc:RXN0-3461 CPD0-2579 + WATER --> CPD-17931 + CPD-17986 This reaction represents DD endopeptidase activity - hydrolysis of the meso-diaminopimelyl-D-alanyl bond in cross-linked peptidoglycan (see |CITS: [23066944]| for nomenclature of endopeptidase activity in E. coli K-12).