KDM8, JMJD5

K10277 KDM8, JMJD5; [protein]-arginine 3-hydroxylase / protease [EC:1.14.11.73 3.4.-.-]

Protein Function: [protein]-arginine 3-hydroxylase / protease [EC:1.14.11.73 3.4.-.-]

DBLinks
Proteins
protein id name function taxonomy source
A0A3B6MTZ6 A0A3B6MTZ6_WHEAT JmjC domain-containing protein Triticum aestivum
A0A9R1H5H4 A0A9R1H5H4_WHEAT JmjC domain-containing protein Triticum aestivum
A0A9R1L0I4 A0A9R1L0I4_WHEAT JmjC domain-containing protein Triticum aestivum
A0A0S2Z5P4 JMJD5 JmjC domain-containing protein 5 Homo sapiens
A0A0S2Z5P8 JMJD5 JmjC domain-containing protein 5 Homo sapiens
A0A0S2Z5T1 JMJD5 Bifunctional peptidase and arginyl-hydroxylase JMJD5 Homo sapiens
A0ABK0LN04 Kdm8 JmjC domain-containing protein 5 Rattus norvegicus
Q8N371 KDM8 Bifunctional peptidase and arginyl-hydroxylase JMJD5 Homo sapiens
Q9CXT6 Kdm8 Bifunctional peptidase and arginyl-hydroxylase JMJD5 Mus musculus
Q497B8 Kdm8 Bifunctional peptidase and arginyl-hydroxylase JMJD5 Rattus norvegicus
Reactions
reaction id name note
KEGG:R12645 [protein]-L-arginine,2-oxoglutarate:oxygen oxidoreductase (3R-hydroxylating) Protein-L-arginine + 2-Oxoglutarate + Oxygen <=> [Protein]-(3R)-3-hydroxy-L-arginine + Succinate + CO2
Rhea:RHEA:56745 L-arginyl-[protein] + 2-oxoglutarate + O2 => (3R)-3-hydroxy-L-arginyl-[protein] + succinate + CO2
Rhea:RHEA:56746 (3R)-3-hydroxy-L-arginyl-[protein] + succinate + CO2 => L-arginyl-[protein] + 2-oxoglutarate + O2
Rhea:RHEA:56747 L-arginyl-[protein] + 2-oxoglutarate + O2 <=> (3R)-3-hydroxy-L-arginyl-[protein] + succinate + CO2
BioCyc:RXN-20590 Protein-L-Arginines + OXYGEN-MOLECULE + 2-KETOGLUTARATE --> Protein-3-Hydroxy-L-Arginines + SUC + CARBON-DIOXIDE
KEGG:R04313 C03793 + 2 C00017<=>C05546 + 2 C00001 multi-step reaction
KEGG:R04869 C05552 + 2 C00012<=>C06250 + 2 C00001 Biocytin + 2 Peptide <=> Holo-[carboxylase] + 2 H2O
KEGG:R10891 C20917 + C00001<=>C20918 + C00188 putative tabtoxin peptidase
BioCyc:RXN-22576 CPD-24805 + WATER --> A-PEPTIDOGLYCAN-MDAP-TRIPEPTIDE + GLY
BioCyc:RXN0-5407 CPD0-1185 + WATER --> A-PEPTIDOGLYCAN-MDAP-TRIPEPTIDE + CPD-24859 This reaction represents hydrolysis of meso-DAP-meso-DAP (3 → 3) cross-links in peptidoglycan (see |CITS: [23066944]| for nomenclature of endopeptidase activity in E. coli K-12).