MAN2
K01231 MAN2; alpha-mannosidase II [EC:3.2.1.114]
Protein Function: alpha-mannosidase II [EC:3.2.1.114]
DBLinks
Proteins
| protein id | name | function | taxonomy source |
|---|---|---|---|
| A0A3B6TNX2 | LOC123165270 | Alpha-mannosidase | Triticum aestivum |
| Q16706 | MAN2A1 | Alpha-mannosidase 2 | Homo sapiens |
| P28494 | Man2a1 | Alpha-mannosidase 2 | Rattus norvegicus |
| P27046 | Man2a1 | Alpha-mannosidase 2 | Mus musculus |
| A0ABK0LWW1 | Man2a1 | Alpha-mannosidase | Rattus norvegicus |
| A0ABK0LU66 | Man2a1 | Alpha-mannosidase | Rattus norvegicus |
| A0ABK0L6J3 | Man2a1 | Alpha-mannosidase | Rattus norvegicus |
| A0A0G2JY93 | Man2a1 | Alpha-mannosidase | Rattus norvegicus |
| A5PKX5 | MAN2A1 | Alpha-mannosidase | Homo sapiens |
| A0A0C4DGL1 | MAN2A2 | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase | Homo sapiens |
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R05984 | G00013 + 2 C00001<=>G00014 + 2 C00936 | G00013 + 2 H2O <=> G00014 + 2 alpha-D-Mannose |
| Rhea:RHEA:56053 | N4-{β-D-GlcNAc-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→3)-[α-D-Man-(1→6)]-α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-β-D-GlcNAc}-L-asparaginyl-[protein] + 2 H2O => 2 α-D-mannopyranose + an N4-{β-D-GlcNAc-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-β-D-GlcNAc}-L-asparaginyl-[protein] | |
| Rhea:RHEA:56054 | 2 α-D-mannopyranose + an N4-{β-D-GlcNAc-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-β-D-GlcNAc}-L-asparaginyl-[protein] => N4-{β-D-GlcNAc-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→3)-[α-D-Man-(1→6)]-α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-β-D-GlcNAc}-L-asparaginyl-[protein] + 2 H2O | |
| Rhea:RHEA:56055 | N4-{β-D-GlcNAc-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→3)-[α-D-Man-(1→6)]-α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-β-D-GlcNAc}-L-asparaginyl-[protein] + 2 H2O <=> 2 α-D-mannopyranose + an N4-{β-D-GlcNAc-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-β-D-GlcNAc}-L-asparaginyl-[protein] | |
| BioCyc:3.2.1.114-RXN | Mannosyl5-N-acetyl-glucosamine2-R + 2 WATER --> 2-N-linked-Glycan + 2 CPD-13559 | |
| BioCyc:RXN-19006 | Man5-GlcNAc3-Xyl-Proteins + 2 WATER --> Man3-GlcNAc3-Xyl-Proteins + 2 CPD-13559 |