Pathways Knowlegdes
Biological pathway database
| Pathway | DOIs | Note |
|---|---|---|
| guanosine nucleotides degradation III Accession ID: BioCyc:FAECPRAU_PWY-6608 |
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| urate biosynthesis/inosine 5'-phosphate degradation Accession ID: BioCyc:COLLINSAERO_PWY-5695 |
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| xanthine and xanthosine salvage Accession ID: BioCyc:COLLINSAERO_SALVPURINE2-PWY |
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| purine nucleotides degradation Accession ID: BioCyc:HUMAN_PWY-6353 |
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| purine nucleotides degradation II (aerobic) Accession ID: BioCyc:META_PWY-6353 |
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Stoychev G, Kierdaszuk B, Shugar D. Xanthosine and xanthine. Substrate properties with purine nucleoside phosphorylases, and relevance to other enzyme systems. Eur J Biochem. 2002 Aug;269(16):4048–57. doi: 10.1046/j.1432-1033.2002.03097.x. PMID: 12180982.; Bzowska A, Kulikowska E, Shugar D. Purine nucleoside phosphorylases: properties, functions, and clinical aspects. Pharmacol Ther. 2000 Dec;88(3):349–425. doi: 10.1016/s0163-7258(00)00097-8. PMID: 11337031.; Witte DP, Wiginton DA, Hutton JJ, Aronow BJ. Coordinate developmental regulation of purine catabolic enzyme expression in gastrointestinal and postimplantation reproductive tracts. J Cell Biol. 1991 Oct;115(1):179–90. PMID: 1918135; PMCID: PMC2289931.; Fox IH. Metabolic basis for disorders of purine nucleotide degradation. Metabolism. 1981 Jun;30(6):616–34. doi: 10.1016/0026-0495(81)90142-6. PMID: 6262603. |
| caffeine degradation III (bacteria, via demethylation) Accession ID: BioCyc:META_PWY-6538 |
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Summers RM, Seffernick JL, Quandt EM, Yu CL, Barrick JE, Subramanian MV. Caffeine Junkie: an Unprecedented Glutathione S-Transferase-Dependent Oxygenase Required for Caffeine Degradation by Pseudomonas putida CBB5. Journal of Bacteriology. 2013 Jun 28;195(17):3933–9. doi: 10.1128/jb.00585-13.; Summers RM, Louie TM, Yu C, Gakhar L, Louie KC, Subramanian M. Novel, Highly Specific N -Demethylases Enable Bacteria To Live on Caffeine and Related Purine Alkaloids. J Bacteriol. 2012 Apr 15;194(8):2041–9. doi: 10.1128/jb.06637-11.; Summers RM, Louie TM, Yu CL, Subramanian M. Characterization of a broad-specificity non-haem iron N-demethylase from Pseudomonas putida CBB5 capable of utilizing several purine alkaloids as sole carbon and nitrogen source. Microbiology (Reading). 2011 Feb;157(Pt 2):583–92. doi: 10.1099/mic.0.043612-0. PMID: 20966097.; Yu CL, Louie TM, Summers R, Kale Y, Gopishetty S, Subramanian M. Two Distinct Pathways for Metabolism of Theophylline and Caffeine Are Coexpressed in Pseudomonas putida CBB5. J Bacteriol. 2009 Jul 15;191(14):4624–32. doi: 10.1128/jb.00409-09.; Dash SS, Gummadi SN. Catabolic pathways and biotechnological applications of microbial caffeine degradation. Biotechnol Lett. 2006 Dec;28(24):1993–2002. doi: 10.1007/s10529-006-9196-2. PMID: 17009088.; Mazzafera P. Catabolism of caffeine in plants and microorganisms. Front Biosci. 2004 May 01;9():1348–59. doi: 10.2741/1339. PMID: 14977550.; HOHNLOSER W, OSSWALD B, LINGENS F. Enzymological Aspects of Caffeine Demethylation and Formaldehyde Oxidation byPseudomonas putidaC1. Hoppe-Seyler´s Zeitschrift für physiologische Chemie. 1980 Jan;361(2):1763–6. doi: 10.1515/bchm2.1980.361.2.1763.; Woolfolk CA. Metabolism of N-methylpurines by a Pseudomonas putida strain isolated by enrichment on caffeine as the sole source of carbon and nitrogen. J Bacteriol. 1975 Sep;123(3):1088–106. doi: 10.1128/jb.123.3.1088-1106.1975. |
| superpathway of guanosine nucleotides degradation (plants) Accession ID: BioCyc:META_PWY-6595 |
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Hesberg C, Hänsch R, Mendel RR, Bittner F. Tandem orientation of duplicated xanthine dehydrogenase genes from Arabidopsis thaliana: differential gene expression and enzyme activities. J Biol Chem. 2004 Apr 02;279(14):13547–54. doi: 10.1074/jbc.m312929200. PMID: 14726515. |
| guanosine nucleotides degradation II Accession ID: BioCyc:META_PWY-6606 |
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Elshafei AM, Abu-Shady MR, el-Beih FM, Mohamed LA. Mode and extent of degradation of adenosine and guanosine by extracts of Aspergillus terricola. Microbiol Res. 1995 Sep;150(3):291–5. doi: 10.1016/s0944-5013(11)80008-x. PMID: 7551735. |
| purine ribonucleosides degradation Accession ID: BioCyc:ECO_PWY0-1296 |
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| guanosine nucleotides degradation III Accession ID: BioCyc:ECO_PWY-6608 |
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Xi H, Schneider BL, Reitzer L. Purine Catabolism in Escherichia coli and Function of Xanthine Dehydrogenase in Purine Salvage. J Bacteriol. 2000 Oct;182(19):5332–41. doi: 10.1128/jb.182.19.5332-5341.2000. |
| xanthine and xanthosine salvage Accession ID: BioCyc:YEAST_SALVPURINE2-PWY |
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| salvage pathways of guanine, xanthine, and their nucleosides Accession ID: BioCyc:TRYPANO_SALVPURINE2-PWY |
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| adenosine nucleotides degradation I Accession ID: BioCyc:PLASMO_PWY-6596 |
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| purine nucleotides degradation I (plants) Accession ID: BioCyc:PLASMO_PWY-5044 |
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| purine ribonucleosides degradation Accession ID: BioCyc:MTBCDC1551_PWY0-1296 |
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| urate biosynthesis/inosine 5'-phosphate degradation Accession ID: BioCyc:ECOO157_PWY-5695 |
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| guanosine nucleotides degradation III Accession ID: BioCyc:ECOO157_PWY-6608 |
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| guanosine nucleotides degradation III Accession ID: BioCyc:ECOL199310_PWY-6608 |
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| purine ribonucleosides degradation Accession ID: BioCyc:ECOL199310_PWY0-1296 |
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| adenosine nucleotides degradation II Accession ID: BioCyc:AURANTIMONAS_SALVADEHYPOX-PWY |
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