Pathways Knowlegdes

Biological pathway database

Pathway DOIs Note
nicotine biosynthesis

Accession ID: PlantCyc:SPENNELLII_PWY-5316		 -
1-methylpyrrolinium biosynthesis

Accession ID: PlantCyc:SPENNELLII_PWY-5315		 -
superpathway of hyoscyamine (atropine) and scopolamine biosynthesis

Accession ID: PlantCyc:CANNUUM_PWY-7341		 -
tropane alkaloids biosynthesis

Accession ID: PlantCyc:EGGPLANT_PWY-5317		 -
superpathway of hyoscyamine (atropine) and scopolamine biosynthesis

Accession ID: PlantCyc:EGGPLANT_PWY-7341		 -
tropane alkaloids biosynthesis

Accession ID: PlantCyc:NTABACUM_TN90_PWY-5317		 -
1-methylpyrrolinium biosynthesis

Accession ID: PlantCyc:PAXILLARIS_PWY-5315		 -
N-methyl-Δ1-pyrrolinium cation biosynthesis

Accession ID: PlantCyc:PLANT_PWY-5315
  • 10.1007/s11103-004-3352-7
  • 10.1073/pnas.0401391101
  • 10.1093/pcp/pcn096
  • 10.1104/pp.100.2.826
  • 10.1104/pp.93.1.216
 Shoji T, Hashimoto T. Why does anatabine, but not nicotine, accumulate in jasmonate-elicited cultured tobacco BY-2 cells? Plant Cell Physiol. 2008 Aug;49(8):1209–16. doi: 10.1093/pcp/pcn096. PMID: 18567891.; Heim WG, Jelesko JG. Association of diamine oxidase and S-adenosylhomocysteine hydrolase in Nicotiana tabacum extracts. Plant Mol Biol. 2004 Sep;56(2):299–308. doi: 10.1007/s11103-004-3352-7. PMID: 15604745.; Zhang L, Ding R, Chai Y, Bonfill M, Moyano E, Oksman-Caldentey K, Xu T, Pi Y, Wang Z, Zhang H, Kai G, Liao Z, Sun X, Tang K. Engineering tropane biosynthetic pathway in Hyoscyamus niger hairy root cultures. Proc. Natl. Acad. Sci. U.S.A. 2004 Apr 14;101(17):6786–91. doi: 10.1073/pnas.0401391101.; Nadim MK, Brenner BM. Glomerular normalcy and pathosis: a 'fin de millénaire' perspective. J Nephrol. 1999 Jul;12 Suppl 2():S16–28. PMID: 10688399.; Hibi N, Fujita T, Hatano M, Hashimoto T, Yamada Y. Putrescine N-Methyltransferase in Cultured Roots of Hyoscyamus albus: n-Butylamine as a Potent Inhibitor of the Transferase both in Vitro and in Vivo. Plant Physiol. 1992 Oct;100(2):826–35. PMID: 16653064; PMCID: PMC1075632.; Hashimoto T, Mitani A, Yamada Y. Diamine Oxidase from Cultured Roots of Hyoscyamus niger: Its Function in Tropane Alkaloid Biosynthesis. Plant Physiol. 1990 May;93(1):216–21. PMID: 16667438; PMCID: PMC1062491.
nicotine biosynthesis

Accession ID: PlantCyc:POTATO_PWY-5316		 -
superpathway of hyoscyamine (atropine) and scopolamine biosynthesis

Accession ID: PlantCyc:POTATO_PWY-7341		 -
calystegine biosynthesis

Accession ID: PlantCyc:CANNUUM_PWY-5318		 -
tropane alkaloids biosynthesis

Accession ID: PlantCyc:TOMATO_PWY-5317		 -
superpathway of nicotine biosynthesis

Accession ID: PlantCyc:CANNUUM_PWY-7342		 -
nicotine biosynthesis

Accession ID: PlantCyc:CANNUUM_PWY-5316		 -
calystegine biosynthesis

Accession ID: PlantCyc:EGGPLANT_PWY-5318		 -
nicotine biosynthesis

Accession ID: PlantCyc:EGGPLANT_PWY-5316		 -
superpathway of hyoscyamine (atropine) and scopolamine biosynthesis

Accession ID: PlantCyc:NTABACUM_TN90_PWY-7341		 -
1-methylpyrrolinium biosynthesis

Accession ID: PlantCyc:NTABACUM_TN90_PWY-5315
  • 10.1007/s11103-004-3352-7
  • 10.1073/pnas.0401391101
  • 10.1093/pcp/pcn096
  • 10.1104/pp.100.2.826
  • 10.1104/pp.93.1.216
 Shoji T, Hashimoto T. Why does anatabine, but not nicotine, accumulate in jasmonate-elicited cultured tobacco BY-2 cells? Plant Cell Physiol. 2008 Aug;49(8):1209–16. doi: 10.1093/pcp/pcn096. PMID: 18567891.; Heim WG, Jelesko JG. Association of diamine oxidase and S-adenosylhomocysteine hydrolase in Nicotiana tabacum extracts. Plant Mol Biol. 2004 Sep;56(2):299–308. doi: 10.1007/s11103-004-3352-7. PMID: 15604745.; Zhang L, Ding R, Chai Y, Bonfill M, Moyano E, Oksman-Caldentey K, Xu T, Pi Y, Wang Z, Zhang H, Kai G, Liao Z, Sun X, Tang K. Engineering tropane biosynthetic pathway in Hyoscyamus niger hairy root cultures. Proc. Natl. Acad. Sci. U.S.A. 2004 Apr 14;101(17):6786–91. doi: 10.1073/pnas.0401391101.; Nadim MK, Brenner BM. Glomerular normalcy and pathosis: a 'fin de millénaire' perspective. J Nephrol. 1999 Jul;12 Suppl 2():S16–28. PMID: 10688399.; Hibi N, Fujita T, Hatano M, Hashimoto T, Yamada Y. Putrescine N-Methyltransferase in Cultured Roots of Hyoscyamus albus: n-Butylamine as a Potent Inhibitor of the Transferase both in Vitro and in Vivo. Plant Physiol. 1992 Oct;100(2):826–35. PMID: 16653064; PMCID: PMC1075632.; Hashimoto T, Mitani A, Yamada Y. Diamine Oxidase from Cultured Roots of Hyoscyamus niger: Its Function in Tropane Alkaloid Biosynthesis. Plant Physiol. 1990 May;93(1):216–21. PMID: 16667438; PMCID: PMC1062491.
superpathway of hyoscyamine (atropine) and scopolamine biosynthesis

Accession ID: PlantCyc:PAXILLARIS_PWY-7341		 -
cocaine biosynthesis

Accession ID: PlantCyc:PLANT_PWY-5843
  • 10.1016/0031-9422(95)00667-2
  • 10.1039/b001713m
  • 10.1055/s-2006-960979
 Humphrey AJ, O'Hagan D. Tropane alkaloid biosynthesis. A century old problem unresolved. Nat Prod Rep. 2001 Oct;18(5):494–502. doi: 10.1039/b001713m. PMID: 11699882.; Huang MN, Abraham TW, Kim SH, Leete E. 1-Methylpyrrolidine-2-acetic Acid is not a Precursor of Tropane Alkaloids. Phytochemistry. 1996 Feb;41(3):767–73. doi: 10.1016/0031-9422(95)00667-2. PMID: 8835455.; Leete E. Recent developments in the biosynthesis of the tropane alkaloids. Planta Med. 1990 Aug;56(4):339–52. doi: 10.1055/s-2006-960979. PMID: 2236285.