Amino Sugar and Nucleotide Sugar Metabolism III

Metabolites

(R)-Lactate

Formula: C3H6O3 (90.0316926)

CAS ID: 10326-41-7

10-Formyltetrahydrofolate

Formula: C20H23N7O7 (473.1658888)

CAS ID: 2800-34-2

2-Oxoglutarate

Formula: C5H6O5 (146.0215226)

CAS ID: 328-50-7

Acetate

Formula: C2H4O2 (60.0211284)

CAS ID: 64-19-7

ADP

Formula: C10H15N5O10P2 (427.02941500000003)

CAS ID: 58-64-0

ADP-glucose

Formula: C16H25N5O15P2 (589.0822360000001)

CAS ID: 2140-58-1

alpha-D-Galactose 1-phosphate

Formula: C6H13O9P (260.0297178)

CAS ID: 2255-14-3

alpha-D-Glucose

Formula: C6H12O6 (180.0633852)

CAS ID: 492-62-6

ATP

Formula: C10H16N5O13P3 (506.9957476)

CAS ID: 56-65-5

beta-D-Glucose 6-phosphate

Formula: C6H13O9P (260.0297178)

CAS ID: 15209-12-8

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

D-Glucosamine 6-phosphate

Formula: C6H14NO8P (259.04570140000004)

CAS ID: 3616-42-0

D-Glucose 6-phosphate

Formula: C6H13O9P (260.0297178)

CAS ID: 56-73-5

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

L-Glutamate

Formula: C5H9NO4 (147.0531554)

CAS ID: 56-86-0

N-Acetyl-D-glucosamine

Formula: C8H15NO6 (221.089933)

CAS ID: 7512-17-6

N-Acetyl-D-glucosamine 6-phosphate

Formula: C8H16NO9P (301.0562656)

CAS ID: 18191-20-3

NAD+

Formula: C21H28N7O14P2 (664.1169428000001)

CAS ID: 53-84-9

NADH

Formula: C21H29N7O14P2 (665.1247674)

CAS ID: 58-68-4

NH4+

Formula: NH4 (18.0343724)

CAS ID: 14798-03-9

Salicyl alcohol

Formula: C7H8O2 (124.05242679999999)

CAS ID: 90-01-7

UDP-glucuronate

Formula: C15H22N2O18P2 (580.0342852)

CAS ID: 2616-64-0

UDP-L-Ara4FN

Formula: C15H23N3O16P2 (563.0553538)

CAS ID:

UTP

Formula: C9H15N2O15P3 (483.968531)

CAS ID: 63-39-8

Chitobiose

Formula: C15H26N2O12 (426.1485676)

CAS ID: 577-76-4

diphosphate

Formula: O7P2 (173.911931)

CAS ID: 14000-31-8

UDP(3-)

Formula: C9H11N2O12P2 (400.9787246)

CAS ID: 86527-70-0



Enzyme

EC Number name full name note
1.1.1.22 UDP-glucose 6-dehydrogenase UDP-alpha-D-glucose:NAD+ 6-oxidoreductase
1.1.1.305 UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) UDP-glucuronate:NAD+ oxidoreductase (decarboxylating)
2.1.2.13 UDP-4-amino-4-deoxy-L-arabinose formyltransferase 10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase
2.4.2.53 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase UDP-4-amino-4-deoxy-alpha-L-arabinose:ditrans,octacis-undecaprenyl phosphate 4-amino-4-deoxy-alpha-L-arabinosyltransferase
2.6.1.87 UDP-4-amino-4-deoxy-L-arabinose aminotransferase UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase
2.7.1.170 anhydro-N-acetylmuramic acid kinase ATP:1,6-anhydro-N-acetyl-beta-muramate 6-phosphotransferase
2.7.1.192 protein-Npi-phosphohistidine-N-acetylmuramate phosphotransferase protein-Npi-phospho-L-histidine:N-acetyl-D-muramate Npi-phosphotransferase
2.7.1.193 protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase protein-Npi-phospho-L-histidine:N-acetyl-D-glucosamine Npi-phosphotransferase
2.7.1.199 protein-Npi-phosphohistidine-D-glucose phosphotransferase protein-Npi-phospho-L-histidine:D-glucose Npi-phosphotransferase
2.7.1.59 N-acetylglucosamine kinase ATP:N-acetyl-D-glucosamine 6-phosphotransferase
2.7.7.12 UDP-glucose-hexose-1-phosphate uridylyltransferase UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2.7.7.27 glucose-1-phosphate adenylyltransferase ATP:alpha-D-glucose-1-phosphate adenylyltransferase
2.7.7.9 UTP-glucose-1-phosphate uridylyltransferase UTP:alpha-D-glucose-1-phosphate uridylyltransferase
3.2.1.14 chitinase (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase
3.2.1.17 lysozyme peptidoglycan N-acetylmuramoylhydrolase
3.2.1.52 beta-N-acetylhexosaminidase beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase
3.2.1.86 6-phospho-beta-glucosidase 6-phospho-beta-D-glucosyl-(1->4)-D-glucose glucohydrolase
3.5.1.25 N-acetylglucosamine-6-phosphate deacetylase N-acetyl-D-glucosamine-6-phosphate amidohydrolase
3.5.99.6 glucosamine-6-phosphate deaminase 2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing)
4.2.1.126 N-acetylmuramic acid 6-phosphate etherase (R)-lactate hydro-lyase (adding N-acetyl-D-glucosamine 6-phosphate; N-acetylmuramate 6-phosphate-forming)
5.3.1.9 glucose-6-phosphate isomerase alpha-D-glucose-6-phosphate aldose-ketose-isomerase (configuration-inverting)
5.4.2.2 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) alpha-D-glucose 1,6-phosphomutase
5.4.2.6 beta-Phosphoglucomutase beta-D-Glucose 1,6-phosphomutase


Pathway Source

Organism Taxonomy Group Enzyme List Source Ratio
Escherichia coli K-12 MAGs 1.1.1.22 / 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.170 / 2.7.1.192 / 2.7.1.193 / 2.7.1.199 / 2.7.1.59 / 2.7.7.12 / 2.7.7.27 / 2.7.7.9 / 3.2.1.14 / 3.2.1.17 / 3.2.1.52 / 3.2.1.86 / 3.5.1.25 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 / 5.4.2.2 / 5.4.2.6 100.00%
Bacillus subtilis subsp. subtilis str. 168 MAGs 1.1.1.22 / 2.6.1.87 / 2.7.1.192 / 2.7.1.193 / 2.7.1.199 / 2.7.1.59 / 2.7.7.12 / 2.7.7.27 / 2.7.7.9 / 3.2.1.17 / 3.2.1.52 / 3.2.1.86 / 3.5.1.25 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 / 5.4.2.2 / 5.4.2.6 78.26%
Enterobacter sp. 638 bacteria 1.1.1.22 / 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.170 / 2.7.1.59 / 2.7.7.12 / 2.7.7.27 / 2.7.7.9 / 3.2.1.17 / 3.2.1.52 / 3.2.1.86 / 3.5.1.25 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 73.91%
Escherichia coli O157:H7 MAGs 1.1.1.22 / 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.170 / 2.7.1.192 / 2.7.1.199 / 2.7.1.59 / 2.7.7.27 / 2.7.7.9 / 3.2.1.52 / 3.5.1.25 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 69.57%
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 MAGs 1.1.1.22 / 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.170 / 2.7.1.199 / 2.7.1.59 / 2.7.7.12 / 2.7.7.27 / 2.7.7.9 / 3.2.1.52 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 65.22%
Escherichia coli CFT073 MAGs 1.1.1.22 / 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.170 / 2.7.1.192 / 2.7.1.199 / 2.7.1.59 / 2.7.7.27 / 2.7.7.9 / 3.2.1.52 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 65.22%
Aeromonas hydrophila subsp. hydrophila ATCC 7966 MAGs 1.1.1.22 / 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.7.27 / 2.7.7.9 / 3.2.1.14 / 3.2.1.17 / 3.2.1.52 / 3.5.1.25 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 / 5.4.2.2 65.22%
Proteus mirabilis HI4320 MAGs 1.1.1.22 / 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.170 / 2.7.7.12 / 2.7.7.9 / 3.2.1.52 / 3.2.1.86 / 3.5.1.25 / 3.5.99.6 / 5.3.1.9 / 5.4.2.2 / 5.4.2.6 65.22%
Vibrio vulnificus CMCP6 MAGs 1.1.1.22 / 2.7.1.170 / 2.7.1.192 / 2.7.1.59 / 2.7.7.27 / 2.7.7.9 / 3.2.1.14 / 3.2.1.52 / 3.2.1.86 / 3.5.1.25 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 / 5.4.2.2 / 5.4.2.6 65.22%
Aeromonas salmonicida subsp. salmonicida MAGs 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.170 / 2.7.1.193 / 2.7.1.199 / 2.7.7.12 / 2.7.7.27 / 2.7.7.9 / 3.5.1.25 / 3.5.99.6 / 5.3.1.9 / 5.4.2.2 60.87%
Enterobacter sp. 63 MAGs 1.1.1.22 / 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.59 / 2.7.7.27 / 3.2.1.52 / 3.2.1.86 / 3.5.1.25 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 / 5.4.2.2 60.87%
Shigella flexneri bacteria 1.1.1.22 / 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.170 / 2.7.1.192 / 2.7.1.59 / 2.7.7.27 / 2.7.7.9 / 3.2.1.52 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 60.87%
Bacillus cereus ATCC 14579 MAGs 1.1.1.22 / 2.7.1.170 / 2.7.1.193 / 2.7.1.199 / 2.7.7.27 / 2.7.7.9 / 3.2.1.14 / 3.2.1.17 / 3.2.1.86 / 3.5.1.25 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 / 5.4.2.2 60.87%
Pseudomonas aeruginosa PAO1 MAGs 1.1.1.22 / 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.170 / 2.7.1.193 / 2.7.7.9 / 3.2.1.17 / 3.2.1.52 / 3.5.1.25 / 5.3.1.9 / 5.4.2.2 56.52%
Streptomyces albogriseolus bacteria 1.1.1.22 / 2.7.1.193 / 2.7.7.12 / 2.7.7.27 / 2.7.7.9 / 3.2.1.14 / 3.2.1.52 / 3.2.1.86 / 3.5.1.25 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 / 5.4.2.2 56.52%
Renibacterium salmoninarum ATCC 33209 MAGs 1.1.1.22 / 2.7.1.59 / 2.7.7.27 / 2.7.7.9 / 3.2.1.14 / 3.2.1.17 / 3.2.1.52 / 3.2.1.86 / 3.5.1.25 / 3.5.99.6 / 5.3.1.9 / 5.4.2.2 52.17%
Shigella boydii Sb227 MAGs 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.170 / 2.7.1.192 / 2.7.1.59 / 2.7.7.27 / 3.2.1.52 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 52.17%
Lactococcus lactis subsp. lactis Il1403 MAGs 2.7.7.12 / 2.7.7.27 / 2.7.7.9 / 3.2.1.14 / 3.2.1.17 / 3.2.1.52 / 3.2.1.86 / 3.5.1.25 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 / 5.4.2.6 52.17%
Streptomyces halstedii bacteria 1.1.1.22 / 2.7.7.12 / 2.7.7.9 / 3.2.1.14 / 3.2.1.17 / 3.2.1.52 / 3.5.1.25 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 / 5.4.2.2 / 5.4.2.6 52.17%
Escherichia coli UTI89 MAGs 1.1.1.305 / 2.1.2.13 / 2.4.2.53 / 2.6.1.87 / 2.7.1.170 / 2.7.1.192 / 2.7.1.59 / 2.7.7.27 / 3.2.1.52 / 3.5.99.6 / 4.2.1.126 / 5.3.1.9 52.17%