Nitrogen Metabolism

Metabolites

2-Oxoglutarate

Formula: C5H6O5 (146.0215226)

CAS ID: 328-50-7

ADP

Formula: C10H15N5O10P2 (427.02941500000003)

CAS ID: 58-64-0

Ammonia

Formula: NH3 (17.0265478)

CAS ID: 7664-41-7

ATP

Formula: C10H16N5O13P3 (506.9957476)

CAS ID: 56-65-5

Carbamate

Formula: CH3NO2 (61.0163778)

CAS ID: 463-77-4

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

HCO3-

Formula: HCO3 (60.9925696)

CAS ID: 71-52-3

L-Glutamate

Formula: C5H9NO4 (147.0531554)

CAS ID: 56-86-0

L-Glutamine

Formula: C5H10N2O3 (146.069139)

CAS ID: 56-85-9

NAD+

Formula: C21H28N7O14P2 (664.1169428000001)

CAS ID: 53-84-9

NADH

Formula: C21H29N7O14P2 (665.1247674)

CAS ID: 58-68-4

NADP+

Formula: C21H29N7O17P3 (744.0832754)

CAS ID: 53-59-8

Nitrogen

Formula: N2 (28.006148)

CAS ID: 7727-37-9

Nitrate

Formula: NO3 (61.987819)

CAS ID: 14797-55-8

Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl],cyclic (3®5)-disulfide

Formula: C24H36N4O6S2 (540.2076156)

CAS ID: 128517-07-7

nitrite

Formula: NO2 (45.992904)

CAS ID: 14797-65-0

phosphate(3-)

Formula: O4P (94.953423)

CAS ID: 14265-44-2

cyanate

Formula: CNO (41.997989)

CAS ID: 71000-82-3



Enzyme

EC Number name full name note
1.4.1.13 glutamate synthase (NADPH) L-glutamate:NADP+ oxidoreductase (transaminating)
1.4.1.4 glutamate dehydrogenase (NADP+) L-glutamate:NADP+ oxidoreductase (deaminating)
1.7.1.15 nitrite reductase (NADH) ammonia:NAD+ oxidoreductase
1.7.2.2 nitrite reductase (cytochrome; ammonia-forming) ammonia:ferricytochrome-c oxidoreductase
1.7.5.1 nitrate reductase (quinone) nitrite:quinone oxidoreductase
1.9.6.1 nitrate reductase (cytochrome) ferrocytochrome:nitrate oxidoreductase
2.7.2.2 carbamate kinase ATP:carbamate phosphotransferase
4.2.1.1 carbonic anhydrase carbonic acid hydro-lyase (carbon-dioxide-forming)
4.2.1.104 cyanase carbamate hydro-lyase
6.3.1.2 glutamine synthetase L-glutamate:ammonia ligase (ADP-forming)


Pathway Source

Organism Taxonomy Group Enzyme List Source Ratio
Escherichia coli K-12 MAGs 1.4.1.13 / 1.4.1.4 / 1.7.1.15 / 1.7.2.2 / 1.7.5.1 / 1.9.6.1 / 2.7.2.2 / 4.2.1.1 / 4.2.1.104 / 6.3.1.2 100.00%
Escherichia coli O157:H7 MAGs 1.7.1.15 / 1.7.2.2 / 1.7.5.1 / 1.9.6.1 / 2.7.2.2 / 4.2.1.1 / 4.2.1.104 / 6.3.1.2 80.00%
Pseudomonas aeruginosa PAO1 MAGs 1.4.1.13 / 1.4.1.4 / 1.9.6.1 / 2.7.2.2 / 4.2.1.1 / 4.2.1.104 / 6.3.1.2 70.00%
Aeromonas hydrophila subsp. hydrophila ATCC 7966 MAGs 1.4.1.13 / 1.4.1.4 / 1.7.2.2 / 1.9.6.1 / 2.7.2.2 / 4.2.1.1 / 6.3.1.2 70.00%
Actinobacillus pleuropneumoniae serovar 7 str. AP76 MAGs 1.4.1.4 / 1.7.2.2 / 1.9.6.1 / 2.7.2.2 / 4.2.1.1 / 6.3.1.2 60.00%
Synechocystis sp. PCC 6803 substr. Kazusa MAGs 1.4.1.4 / 1.7.5.1 / 2.7.2.2 / 4.2.1.1 / 4.2.1.104 / 6.3.1.2 60.00%
Synechocystis sp. PCC 6803 bacteria 1.4.1.13 / 1.4.1.4 / 2.7.2.2 / 4.2.1.1 / 4.2.1.104 / 6.3.1.2 60.00%
Streptomyces albogriseolus bacteria 1.4.1.13 / 1.4.1.4 / 1.7.1.15 / 1.7.5.1 / 4.2.1.1 / 6.3.1.2 60.00%
Cupriavidus taiwanensis bacteria 1.4.1.13 / 1.4.1.4 / 1.7.1.15 / 4.2.1.1 / 4.2.1.104 / 6.3.1.2 60.00%
Pseudomonas entomophila L48 MAGs 1.4.1.13 / 1.4.1.4 / 2.7.2.2 / 4.2.1.1 / 4.2.1.104 / 6.3.1.2 60.00%
Aeromonas salmonicida subsp. salmonicida MAGs 1.4.1.13 / 1.4.1.4 / 1.7.1.15 / 1.7.2.2 / 2.7.2.2 / 6.3.1.2 60.00%
Laribacter hongkongensis HLHK9 MAGs 1.4.1.13 / 1.4.1.4 / 1.9.6.1 / 2.7.2.2 / 4.2.1.1 / 6.3.1.2 60.00%
Sinorhizobium meliloti 1021 MAGs 1.4.1.13 / 1.4.1.4 / 1.9.6.1 / 2.7.2.2 / 4.2.1.1 / 6.3.1.2 60.00%
Chromobacterium violaceum ATCC 12472 MAGs 1.4.1.13 / 2.7.2.2 / 4.2.1.1 / 4.2.1.104 / 6.3.1.2 50.00%
Shigella flexneri bacteria 1.7.2.2 / 1.7.5.1 / 1.9.6.1 / 4.2.1.1 / 6.3.1.2 50.00%
Streptococcus mutans UA159 MAGs 1.4.1.13 / 1.4.1.4 / 2.7.2.2 / 4.2.1.1 / 6.3.1.2 50.00%
Burkholderia pseudomallei K96243 MAGs 1.4.1.13 / 2.7.2.2 / 4.2.1.1 / 4.2.1.104 / 6.3.1.2 50.00%
Haemophilus influenzae Rd KW20 MAGs 1.4.1.4 / 1.7.2.2 / 2.7.2.2 / 4.2.1.1 / 6.3.1.2 50.00%
Burkholderia mallei ATCC 23344 MAGs 1.4.1.13 / 2.7.2.2 / 4.2.1.1 / 4.2.1.104 / 6.3.1.2 50.00%
Paraburkholderia graminis bacteria 1.4.1.13 / 1.7.1.15 / 1.7.5.1 / 4.2.1.1 / 6.3.1.2 50.00%