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The 2-formyl derivative of glutaric acid." []

2-Oxoadipic acid is produced from lysine in the cytosol of cells via the saccharopine and the pipecolic acid pathways. Catabolites of hydroxylysine and tryptophan enter these pathways as 2-aminoadipic- -semialdehyde and 2-oxoadipate, respectively. In the matrix of mitochondria, 2-oxoadipate is decarboxylated to glutaryl-CoA by the 2-oxoadipate dehydrogenase complex and then converted to acetyl-CoA. 2-Oxoadipic aciduria is an in-born error of metabolism of lysine, tryptophan, and hydroxylysine, in which abnormal quantities of 2-aminoadipic acid are found in body fluids along with 2-oxoadipic acid. Patients with 2-Oxoadipic acidemias are mentally retarded with hypotonia or seizures. 2-Oxoadipic aciduria can occur in patients with Kearns-Sayre Syndrome, a progressive disorder with onset prior to 20 years of age in which multiple organ systems are affected, including progressive external ophthalmoplegia, retinopathy, and the age of onset, and these are associated classically with abnormalities in cardiac conduction, cerebellar signs, and elevated cerebrospinal fluid protein (PMID: 10655159, 16183823, 11083877). Oxoadipic acid is found to be associated with alpha-aminoadipic aciduria, which is an inborn error of metabolism.

3-Oxoadipic acid is a regularly occurring Adipic dicarboxylic acid human metabolite found occasionally in biofluids of healthy individuals. (PMIDs 8340451, 1769109, 2338430) Increased amounts of 3-Oxoadipic acid are excreted after ingestion of Sebacic acid, supporting the hypothesis that dicarboxylic acids are degraded by ordinary beta-oxidation. (PMID 3220884).

3D-3,5/4-trihydroxycyclohexane-1,2-dione is a 3,5/4-trihydroxycyclohexane-1,2-dione and a secondary alpha-hydroxy ketone. It is a tautomer of a (4R,5S,6R)-2,4,5,6-tetrahydroxycyclohex-2-en-1-one.

A member of the class of cyclohexenones that is cyclohex-2-en-1-one substituted by hydroxy groups at positions 2, 4, 5 and 6 (the 4R,5S,6R-stereoisomer)." []

2-Methyl-4-oxopentanedioic acid is found in fruits. 2-Methyl-4-oxopentanedioic acid is a constituent of Tamarindus indica (tamarind).

(2r,3s)-2,3-dimethylmalate is soluble (in water) and a weakly acidic compound (based on its pKa). (2r,3s)-2,3-dimethylmalate can be found in a number of food items such as pepper (c. frutescens), oregon yampah, green bean, and red raspberry, which makes (2r,3s)-2,3-dimethylmalate a potential biomarker for the consumption of these food products.

A dicarboxylic acid dianion that results from the removal of a proton from both of the carboxylic acid groups of 3-hydroxy-3-methylglutaric acid." []

The conjugate base of (R)-2-hydroxyadipic acid." []

Dicarboxylate anion of 2-hydroxymethylglutaric acid." []

The dicarboxylate anion of (S)-2-hydroxymethylglutaric acid; mahor microspecies at pH 7.3." []

Dicarboxylate anion of (2R,3S)-2,3-dimethylmalic acid." []

Dicarboxylate anion of (R)-2-ethylmalic acid." []

Dicarboxylate anion of (R)-3,3-dimethylmalic acid." []

Dicarboxylate anion of 3-ethylmalic acid." []