(-)-5-Oxo-1,2-campholide (BioCAD00000000004)
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Metabolite Card
Chinese Name: (-)-5-氧代-1,2-樟脑脂
Formula: C10H14O3 (182.0943)
SMILES:
CC1(C)(C2(C)(OC(=O)CC1C(=O)C2))Synonyms [en]
(-)-5-Oxo-1,2-campholide; (1R,5R)-1,8,8-trimethyl-2-oxabicyclo[3.2.1]octane-3,6-dione; (1S,5S)-1,8,8-Trimethyl-2-oxabicyclo[3.2.1]octane-3,6-dione; 1,8,8-trimethyl-2-oxabicyclo[3.2.1]octane-3,6-dione
Synonyms [zh]
左旋-5-酮基-1,2-莰醇
Last reviewed on 2026-04-16.
Cite this Page
(-)-5-Oxo-1,2-campholide. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/5-Oxo-1,2-campholide
(retrieved
2026-08-20) (CAD Registry RN: BioCAD00000000004). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Abstract: (-)-5-Oxo-1,2-campholide, a structurally modified camphor derivative, exhibits potential biological activities rooted in its unique oxo-functionalized structure. Preliminary evidence suggests it may possess anti-inflammatory properties, potentially through modulation of pro-inflammatory pathways (e.g., COX-2 inhibition), akin to related camphor derivatives. Its antimicrobial activity could arise from membrane-disrupting effects, common to terpenoid compounds. Additionally, the compound may interact with neuropharmacological targets, such as GABA receptors, hinting at possible anxiolytic or anticonvulsant effects. However, its specific mechanisms, efficacy, and safety profile remain under investigation, necessitating further studies to validate these hypotheses and explore therapeutic applications.
DBLinks
- CAS Registry Number:
- PubChem CID:
- ChEBI:
- HMDB:
- LipidMaps:
- KEGG: C21930
- BioCyc: --5-oxo-1-2-campholide
- NCBI MeSH:
- Wikipedia:
Other DBLinks
- KEGG: C02952
- KEGG: C21930
- BioCyc: --5-oxo-1-2-campholide
- Metlin: METLIN_53343
Class / Ontology
| ID | EC Number | Name |
|---|---|---|
| KEGG:R12149 | 1.14.14.155 | (-)-bornane-2,5-dione,FMNH2:oxygen oxidoreductase (1,2-lactonizing) |
| KEGG:R13091 | C21930<=>C20271 | |
| BioCyc:RXN-13043 | 1.14.14.155 | CPD-14061 + FMNH2 + OXYGEN-MOLECULE --> --5-oxo-1-2-campholide + WATER + FMN + PROTON |
| BioCyc:RXN-13044 | --5-oxo-1-2-campholide --> CPD-866 + PROTON |