EC: 4.1.1.50

adenosylmethionine decarboxylase (S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-salt-forming])

enzyme lambda metabolic reaction experiment
- [Putrescine]

S_Adenosyl_L_methionine -> CO2 + S_Adenosylmethioninamine		 (( (( (( (cytosol * Vmaxsamdc) ) / (1 + (S / Kissamdc))) ) * SAM) ) / (( (Kmsamdc * (( (1 + (Kapsamdc / P)) ) + (A / Kiasamdc))) ) + SAM)) buffer: *
PH: 7
Temperature: 36
uniprot:Q57763 [adenosylmethionine decarboxylase(Enzyme) wildtype]

S_Adenosyl_L_methionine -> CO2 + S_Adenosylmethioninamine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Hepes-KOH, 5 mM EDTA
PH: 7.5
Temperature: 22
uniprot:O76240 [Putrescine]

S_Adenosyl_L_methionine -> CO2 + S_Adenosylmethioninamine		 (( (Vmax * S) ) / (Km_app + S)) buffer: 50 mM Tris-HCl, 1.25 mM DTT
PH: 7.4
Temperature: 36

Pathways

pathway id name
BioCyc:META_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
BioCyc:ECO_POLYAMSYN-PWY superpathway of polyamine biosynthesis I
BioCyc:ARA_PWYQT-94 superpathway of polyamine biosynthesis
BioCyc:ANTHRA_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
BioCyc:ANTHRA_ARGSPECAT-PWY spermine biosynthesis
BioCyc:META_ARGSPECAT-PWY Spermine Syn
BioCyc:META_POLYAMSYN-PWY superpathway of polyamine biosynthesis I
BioCyc:META_PWY-7528 L-methionine salvage cycle I (bacteria and plants)
BioCyc:ECO_ARG+POLYAMINE-SYN superpathway of arginine and polyamine biosynthesis
BioCyc:ARA_PWY-7528 L-methionine salvage cycle I (bacteria and plants)
BioCyc:ARA_ARGSPECAT-PWY spermine biosynthesis
BioCyc:ECOL199310_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
BioCyc:YEAST_ARGSPECAT-PWY spermine and methylthioadenosine biosynthesis
BioCyc:ARA_PWY0-461 L-lysine degradation I
BioCyc:ECOO157_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
BioCyc:META_ARG+POLYAMINE-SYN superpathway of arginine and polyamine biosynthesis
BioCyc:ECO_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
BioCyc:YEAST_BSUBPOLYAMSYN-PWY spermidine and methylthioadenosine biosynthesis
BioCyc:ARA_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
BioCyc:BSUB_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
PathBank:SMP0000857 S-Adenosyl-L-Methionine Biosynthesis
PathBank:SMP0002054 Spermidine Biosynthesis I
PathBank:SMP0002097 Spermidine Biosynthesis and Metabolism
PlantCyc:ARA_PWY0-461 L-lysine degradation I
PlantCyc:ARA_POLYAMINSYN3-PWY superpathway of polyamine biosynthesis II
PlantCyc:ARA_ARGSPECAT-PWY spermine biosynthesis
PlantCyc:ARA_PWY-7528 L-methionine salvage cycle I (bacteria and plants)
PlantCyc:ARA_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-71291 Amino acid and derivative metabolism
Reactome:R-CEL-351202 Metabolism of polyamines
Reactome:R-HSA-351202 Metabolism of polyamines
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-351202 Metabolism of polyamines
Reactome:R-RNO-351202 Metabolism of polyamines
Reactome:R-SCE-71291 Amino acid and derivative metabolism
Reactome:R-SPO-1430728 Metabolism
Reactome:R-BTA-351202 Metabolism of polyamines
Reactome:R-DDI-71291 Amino acid and derivative metabolism
Reactome:R-DME-1430728 Metabolism
Reactome:R-DME-71291 Amino acid and derivative metabolism
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SCE-351202 Metabolism of polyamines
Reactome:R-SPO-71291 Amino acid and derivative metabolism
Reactome:R-CEL-71291 Amino acid and derivative metabolism
Reactome:R-HSA-71291 Amino acid and derivative metabolism
Reactome:R-MMU-71291 Amino acid and derivative metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-71291 Amino acid and derivative metabolism
Reactome:R-CEL-1430728 Metabolism
Reactome:R-DDI-1430728 Metabolism
Reactome:R-DDI-351202 Metabolism of polyamines
Reactome:R-DME-351202 Metabolism of polyamines
Reactome:R-HSA-1430728 Metabolism
Reactome:R-SPO-351202 Metabolism of polyamines
PathBank:SMP0120718 Hypermethioninemia
PathBank:SMP0000177 Cystathionine beta-Synthase Deficiency
PathBank:SMP0000340 Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)
PathBank:SMP0087342 Methionine Metabolism
PathBank:SMP0087442 Spermidine and Spermine Biosynthesis
PathBank:SMP0120853 Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
PathBank:SMP0120471 Cystathionine beta-Synthase Deficiency
PathBank:SMP0120487 Glycine N-Methyltransferase Deficiency
PathBank:SMP0120519 Methionine Adenosyltransferase Deficiency
PathBank:SMP0120527 S-Adenosylhomocysteine (SAH) Hydrolase Deficiency
PathBank:SMP0000033 Methionine Metabolism
PathBank:SMP0000222 Glycine N-Methyltransferase Deficiency
PathBank:SMP0002307 beta-Alanine Metabolism
PathBank:SMP0063637 Methionine Metabolism
PathBank:SMP0120634 Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
PathBank:SMP0121301 S-Adenosyl-L-Methionine Biosynthesis
PathBank:SMP0122229 Spermidine Biosynthesis I
PathBank:SMP0000341 Hypermethioninemia
PathBank:SMP0000221 Methionine Adenosyltransferase Deficiency
PathBank:SMP0002434 Lysine Metabolism
PathBank:SMP0087308 Spermidine and Spermine Biosynthesis
PathBank:SMP0063671 Spermidine and Spermine Biosynthesis
PathBank:SMP0120691 Cystathionine beta-Synthase Deficiency
PathBank:SMP0120707 Glycine N-Methyltransferase Deficiency
PathBank:SMP0120739 Methionine Adenosyltransferase Deficiency
PathBank:SMP0120747 S-Adenosylhomocysteine (SAH) Hydrolase Deficiency
PathBank:SMP0120498 Hypermethioninemia
PathBank:SMP0000445 Spermidine and Spermine Biosynthesis
PathBank:SMP0000214 S-Adenosylhomocysteine (SAH) Hydrolase Deficiency
PathBank:SMP0000570 Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
PathBank:SMP0087483 Methionine Metabolism