EC: 1.1.1.85

3-isopropylmalate dehydrogenase ((2R,3S)-3-isopropylmalate:NAD+ oxidoreductase)

enzyme lambda metabolic reaction experiment
uniprot:Q58130 [3-isopropylmalate dehydrogenase(Enzyme) wildtype MJ0720]

3_Isopropylmalate + NAD+ -> H+ + CO2 + 4_Methyl_2_oxopentanoate + NADH		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM TAPS-KOH, 200 mM KCl, 10 mM MgCl2
PH: 8.5
Temperature: 60

Pathways

pathway id name
BioCyc:MTBH37RV_LEUSYN-PWY L-leucine biosynthesis
BioCyc:CAULO_LEUSYN-PWY leucine biosynthesis
BioCyc:ANTHRA_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched amino acid biosynthesis
BioCyc:ANTHRA_LEUSYN-PWY L-leucine biosynthesis
BioCyc:BSUB_LEUSYN-PWY L-leucine biosynthesis
BioCyc:BTHE_LEUSYN-PWY leucine biosynthesis
BioCyc:BTHE_BRANCHED-CHAIN-AA-SYN-PWY superpathway of leucine, valine, and isoleucine biosynthesis
BioCyc:CORYNE_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched amino acid biosynthesis
BioCyc:GCF_000013425_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched chain amino acid biosynthesis
BioCyc:META_PWY-7396 butanol and isobutanol biosynthesis (engineered)
BioCyc:ARA_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched chain amino acid biosynthesis
BioCyc:VCHO_LEUSYN-PWY L-leucine biosynthesis
BioCyc:MTBCDC1551_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched amino acid biosynthesis
BioCyc:SYNEL_LEUSYN-PWY L-leucine biosynthesis
BioCyc:SYNEL_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched amino acid biosynthesis
BioCyc:META_PWY-5101 L-isoleucine biosynthesis II
BioCyc:ARA_LEUSYN-PWY L-leucine biosynthesis
BioCyc:VCHO_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched chain amino acid biosynthesis
BioCyc:MTBH37RV_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched chain amino acid biosynthesis
BioCyc:MTBCDC1551_LEUSYN-PWY L-leucine biosynthesis
BioCyc:CAULO_BRANCHED-CHAIN-AA-SYN-PWY superpathway of leucine, valine, and isoleucine biosynthesis
BioCyc:AGRO_LEUSYN-PWY L-leucine biosynthesis
BioCyc:BSUB_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched chain amino acid biosynthesis
BioCyc:ECOL316407_BRANCHED-CHAIN-AA-SYN-PWY superpathway of leucine, valine, and isoleucine biosynthesis
BioCyc:CORYNE_LEUSYN-PWY L-leucine biosynthesis
BioCyc:META_PWY-7649 3-hydroxy-L-homotyrosine biosynthesis
BioCyc:AGRO_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched chain amino acid biosynthesis
BioCyc:ECOL316407_LEUSYN-PWY leucine biosynthesis
BioCyc:GCF_000013425_LEUSYN-PWY L-leucine biosynthesis
PathBank:SMP0000831 Leucine Biosynthesis
PathBank:SMP0000994 Secondary Metabolites: Valine and L-Leucine Biosynthesis from Pyruvate
PathBank:SMP0000996 Secondary Metabolites: Leucine Biosynthesis
PlantCyc:ARA_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched chain amino acid biosynthesis
PlantCyc:ARA_LEUSYN-PWY L-leucine biosynthesis
PlantCyc:PLANT_LEUSYN-PWY L-leucine biosynthesis
PathBank:SMP0121204 L-Homomethionine Biosynthesis