EC: 1.1.1.38

malate dehydrogenase (oxaloacetate-decarboxylating) ((S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating))

enzyme lambda metabolic reaction experiment
uniprot:P23368 [Fumarate]

L_Malate + NAD+ -> NADH + CO2 + Pyruvate + H+		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) wildtype]

NAD+ + L_Malate -> NADH + CO2 + H+ + Pyruvate		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) wildtype]

L_Malate + NADP+ -> Pyruvate + NADPH + H+ + CO2		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

NAD+ + L_Malate -> NADH + Pyruvate + H+ + CO2		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NAD+ -> H+ + NADH + CO2 + Pyruvate		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NADP+ -> Pyruvate + CO2 + NADPH + H+		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NADP+ -> CO2 + Pyruvate + H+ + NADPH		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NADP+ -> NADPH + Pyruvate + CO2 + H+		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) mutant Q362A]

L_Malate + NAD+ -> Pyruvate + CO2 + H+ + NADH		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) mutant Q362K]

NAD+ + L_Malate -> Pyruvate + H+ + CO2 + NADH		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) mutant Q362A]

NADP+ + L_Malate -> Pyruvate + NADPH + CO2 + H+		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) mutant Q362K]

NADP+ + L_Malate -> CO2 + NADPH + Pyruvate + H+		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NAD+ -> H+ + NADH + CO2 + Pyruvate		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NAD+ -> NADH + CO2 + Pyruvate + H+		 (( (Vmax * A) ) / (A + (Km * (1 + (I / Ki))))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

NAD+ + L_Malate -> Pyruvate + NADH + CO2 + H+		 (( (Vmax * A) ) / (A + (Km * (1 + (I / Ki))))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NAD+ -> CO2 + H+ + Pyruvate + NADH		 (( (Vmax * A) ) / (A + (Km * (1 + (I / Ki))))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NADP+ -> NADPH + H+ + CO2 + Pyruvate		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NADP+ -> H+ + CO2 + NADPH + Pyruvate		 (( (Vmax * A) ) / (A + (Km * (1 + (I / Ki))))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NADP+ -> H+ + CO2 + Pyruvate + NADPH		 (( (Vmax * A) ) / (A + (Km * (1 + (I / Ki))))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) mutant Q362N]

NAD+ + L_Malate -> NADH + H+ + CO2 + Pyruvate		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) mutant Q362N]

L_Malate + NADP+ -> NADPH + CO2 + H+ + Pyruvate		 (( (Vmax * (A ^ h)) ) / (( (K_05 ^ h) ) + (A ^ h))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NAD+ -> NADH + CO2 + H+ + Pyruvate		 (( (Vmax * A) ) / (A + (Km * (1 + (I / Ki))))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NADP+ -> H+ + CO2 + NADPH + Pyruvate		 (( (Vmax * A) ) / (A + (Km * (1 + (I / Ki))))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

NADP+ + L_Malate -> NADPH + H+ + CO2 + Pyruvate		 (( (Vmax * A) ) / (A + (Km * (1 + (I / Ki))))) buffer: 50 mM Tris-HCl, 10 mM Mg2+
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

NAD+ + L_Malate -> Pyruvate + CO2 + NADH + H+		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 3 mM MnCl2
PH: 7.4
Temperature: 37
uniprot:P23368 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) wildtype isoenzym ME2]

L_Malate + NAD+ -> CO2 + H+ + NADH + Pyruvate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 3 mM MnCl2
PH: 7.4
Temperature: 37
uniprot:P26616 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) wildtype]

L_Malate + NAD+ -> CO2 + Pyruvate + NADH + H+		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 3 mM MnCl2
PH: 7.4
Temperature: 37
uniprot:P23368 [Fumarate]

L_Malate + NAD+ -> CO2 + Pyruvate + NADH + H+		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris/HCl, 0.5 mM oxamate
PH: 7.2
Temperature: 37
uniprot:P23368 [Fumarate]

NAD+ + L_Malate -> NADH + H+ + CO2 + Pyruvate		 (( (Vmax * B) ) / (Km + B)) buffer: 100 mM Tris/HCl, 0.5 mM oxamate
PH: 7.2
Temperature: 37
uniprot:P23368 [Mn2+]

L_Malate + NAD+ -> CO2 + H+ + NADH + Pyruvate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris/HCl, 0.5 mM oxamate
PH: 7.2
Temperature: 37
uniprot:P23368 [Mn2+]

NAD+ + L_Malate -> NADH + CO2 + H+ + Pyruvate		 (( (Vmax * B) ) / (Km + B)) buffer: 100 mM Tris/HCl, 0.5 mM oxamate
PH: 7.2
Temperature: 37
uniprot:P27443 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) mutant Y126F]

NAD+ + L_Malate -> CO2 + Pyruvate + NADH		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 200 mM MgSO4
PH: 7.5
Temperature: 24.9
uniprot:P27443 [malate dehydrogenase (oxaloacetate-decarboxylating)(Enzyme) mutant Y126F]

L_Malate + NAD+ -> CO2 + Pyruvate + NADH		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 200 mM MgSO4
PH: 5.8
Temperature: 24.9
uniprot:P23368 [Fumarate]

L_Malate + NAD+ -> CO2 + NADH + Pyruvate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NAD+ -> NADH + Pyruvate + CO2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NAD+ -> CO2 + NADH + Pyruvate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

NAD+ + L_Malate -> NADH + CO2 + Pyruvate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

L_Malate + NAD+ -> Pyruvate + NADH + CO2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

L_Malate + NAD+ -> NADH + CO2 + Pyruvate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

NAD+ + L_Malate -> CO2 + Pyruvate + NADH		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

NAD+ + L_Malate -> NADH + CO2 + Pyruvate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

NAD+ + L_Malate -> NADH + Pyruvate + CO2		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NAD+ -> NADH + Pyruvate + CO2		 (( (( (E * kcat) ) * C) ) / (Km + C)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NAD+ -> Pyruvate + CO2 + NADH		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

NAD+ + L_Malate -> Pyruvate + NADH + CO2		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

NAD+ + L_Malate -> Pyruvate + CO2 + NADH		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

NAD+ + L_Malate -> Pyruvate + NADH + CO2		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

L_Malate + NAD+ -> CO2 + NADH + Pyruvate		 (( (( (E * kcat) ) * C) ) / (Km + C)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

NAD+ + L_Malate -> CO2 + Pyruvate + NADH		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

NAD+ + L_Malate -> CO2 + Pyruvate + NADH		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

L_Malate + NAD+ -> NADH + Pyruvate + CO2		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

NAD+ + L_Malate -> CO2 + NADH + Pyruvate		 (( (E * kcat) ) / (( (1 + (Km / B)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NAD+ -> CO2 + NADH + Pyruvate		 (( (E * kcat) ) / (( (1 + (Km / B)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NAD+ -> CO2 + NADH + Pyruvate		 (( (E * kcat) ) / (( (1 + (Km / B)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NAD+ -> Pyruvate + CO2 + NADH		 (( (( (E * kcat) ) * C) ) / (Km + C)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

NAD+ + L_Malate -> Pyruvate + NADH + CO2		 (( (( (E * kcat) ) * C) ) / (Km + C)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Fumarate]

L_Malate + NAD+ -> NADH + Pyruvate + CO2		 (( (( (E * kcat) ) * C) ) / (Km + C)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

NAD+ + L_Malate -> Pyruvate + NADH + CO2		 (( (( (E * kcat) ) * C) ) / (Km + C)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

NAD+ + L_Malate -> Pyruvate + CO2 + NADH		 (( (( (E * kcat) ) * C) ) / (Km + C)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [Mg2+]

NAD+ + L_Malate -> NADH + CO2 + Pyruvate		 (( (( (E * kcat) ) * C) ) / (Km + C)) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

NAD+ + L_Malate -> NADH + CO2 + Pyruvate		 (( (E * kcat) ) / (( (1 + (Km / A)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NAD+ -> Pyruvate + NADH + CO2		 (( (E * kcat) ) / (( (1 + (Km / A)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

NAD+ + L_Malate -> NADH + CO2 + Pyruvate		 (( (E * kcat) ) / (( (1 + (Km / B)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NAD+ -> NADH + CO2 + Pyruvate		 (( (E * kcat) ) / (( (1 + (Km / B)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

NAD+ + L_Malate -> CO2 + NADH + Pyruvate		 (( (E * kcat) ) / (( (1 + (Km / B)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NAD+ -> CO2 + NADH + Pyruvate		 (( (E * kcat) ) / (( (1 + (Km / A)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

NAD+ + L_Malate -> CO2 + Pyruvate + NADH		 (( (E * kcat) ) / (( (1 + (Km / A)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

NAD+ + L_Malate -> NADH + CO2 + Pyruvate		 (( (E * kcat) ) / (( (1 + (Km / B)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NAD+ -> Pyruvate + NADH + CO2		 (( (E * kcat) ) / (( (1 + (Km / B)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NAD+ -> Pyruvate + CO2 + NADH		 (( (E * kcat) ) / (( (1 + (Km / A)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

NAD+ + L_Malate -> Pyruvate + NADH + CO2		 (( (E * kcat) ) / (( (1 + (Km / A)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

L_Malate + NAD+ -> NADH + CO2 + Pyruvate		 (( (E * kcat) ) / (( (1 + (Km / A)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
uniprot:P23368 [ATP]

NAD+ + L_Malate -> Pyruvate + CO2 + NADH		 (( (E * kcat) ) / (( (1 + (Km / A)) ) / (1 + (I / Ki)))) buffer: 50 mM Tris/HCl
PH: 7.4
Temperature: 30
- [ATP]

L_Malate + NAD+ -> CO2 + Pyruvate + NADH		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 30 mM Tris-HCl, 2 mM MnCl2
PH: 7.4
Temperature: 30
- [ATP]

L_Malate + NAD+ -> Pyruvate + CO2 + NADH		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 30 mM Tris-HCl, 2 mM MnCl2
PH: 7.4
Temperature: 30
- [ATP]

L_Malate + NAD+ -> Pyruvate + CO2 + NADH		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 30 mM Tris-HCl, 2 mM MnCl2
PH: 7.4
Temperature: 30
- [ATP]

L_Malate + NAD+ -> NADH + CO2 + Pyruvate		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 30 mM Tris-HCl, 2 mM MnCl2
PH: 7.4
Temperature: 30
- [ATP]

NAD+ + L_Malate -> CO2 + NADH + Pyruvate		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 30 mM Tris-HCl, 2 mM MnCl2
PH: 7.4
Temperature: 30
- [ATP]

NAD+ + L_Malate -> NADH + CO2 + Pyruvate		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 30 mM Tris-HCl, 2 mM MnCl2
PH: 7.4
Temperature: 30
- [ATP]

L_Malate + NAD+ -> NADH + Pyruvate + CO2		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 30 mM Tris-HCl, 2 mM MnCl2
PH: 7.4
Temperature: 30
- [Fumarate]

L_Malate + NAD+ -> Pyruvate + CO2 + NADH		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 30 mM Tris-HCl
PH: 7.4
Temperature: 30
- [Fumarate]

NAD+ + L_Malate -> NADH + CO2 + Pyruvate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 30 mM Tris-HCl
PH: 7.4
Temperature: 30
- [Fumarate]

L_Malate + NAD+ -> Pyruvate + CO2 + NADH		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 30 mM Tris-HCl
PH: 7.4
Temperature: 30
- [ATP]

L_Malate + NAD+ -> Pyruvate + CO2 + NADH		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 30 mM Tris-HCl, 2 mM MnCl2
PH: 7.4
Temperature: 30
- [ATP]

L_Malate + NAD+ -> NADH + Pyruvate + CO2		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 30 mM Tris-HCl, 2 mM MnCl2
PH: 7.4
Temperature: 30
- [ATP]

NAD+ + L_Malate -> NADH + Pyruvate + CO2		 (( (( (E * kcat) ) * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 30 mM Tris-HCl, 2 mM MnCl2
PH: 7.4
Temperature: 30
- [Fumarate]

NAD+ + L_Malate -> NADH + Pyruvate + CO2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 30 mM Tris-HCl
PH: 7.4
Temperature: 30
- [Fumarate]

NAD+ + L_Malate -> NADH + CO2 + Pyruvate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 30 mM Tris-HCl
PH: 7.4
Temperature: 30
uniprot:P26616 [Mg2+]

L_Malate + NAD+ -> Pyruvate + NADH + H+ + CO2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris-HCl
PH: 7.5
Temperature: 30
uniprot:P26616 [Mg2+]

NADP+ + L_Malate -> H+ + Pyruvate + NADPH + CO2		 (( (( (E * kcat) ) * (A ^ n)) ) / (( (A_half ^ n) ) + (A ^ n))) buffer: 50 mM Tris-HCl
PH: 7.5
Temperature: 30
uniprot:P26616 [Mg2+]

NADH + CO2 + Pyruvate + H+ -> NAD+ + L_Malate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM MOPS-KOH
PH: 7
Temperature: 30
uniprot:P26616 [Mg2+]

L_Malate + NAD+ -> NADH + H+ + CO2 + Pyruvate		 (( (Vmax * M) ) / (Km + M)) buffer: 50 mM Tris-HCl
PH: 7.5
Temperature: 30
uniprot:P26616 [Mg2+]

NAD+ + L_Malate -> CO2 + NADH + H+ + Pyruvate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl
PH: 7.5
Temperature: 30

Pathways

pathway id name
BioCyc:META_PWY-7118 chitin degradation to ethanol
BioCyc:META_PWY-3641 L-carnitine degradation III
BioCyc:META_PWY-7384 anaerobic energy metabolism (invertebrates, mitochondrial)
BioCyc:META_PWY-7686 L-malate degradation II
BioCyc:ECO_GLUCONEO-PWY gluconeogenesis I
BioCyc:YEAST_PWY-7118 chitin degradation to ethanol
BioCyc:YEAST_PWY-7686 L-malate degradation II
BioCyc:MOUSE_GLUCONEO-PWY gluconeogenesis I
BioCyc:META_PWY-7389 superpathway of anaerobic energy metabolism (invertebrates)
BioCyc:MTBH37RV_GLUCONEO-PWY gluconeogenesis I
BioCyc:MTBH37RV_PWY-7686 L-malate degradation II
BioCyc:MTBCDC1551_GLUCONEO-PWY gluconeogenesis I
BioCyc:ECOL316407_GLUCONEO-PWY gluconeogenesis I
BioCyc:META_GLUCONEO-PWY gluconeogenesis I
BioCyc:YEAST_GLUCONEO-YEAST-PWY gluconeogenesis
BioCyc:BSUB_GLUCONEO-PWY-1 gluconeogenesis I
PathBank:SMP0000839 Gluconeogenesis from L-Malic Acid
PathBank:SMP0002355 Pyruvate Metabolism