EC: 1.2.1.41

glutamate-5-semialdehyde dehydrogenase (L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating))

enzyme lambda metabolic reaction experiment
uniprot:Q9HX20 [glutamate-5-semialdehyde dehydrogenase(Enzyme) wildtype]

L_Glutamate_5_semialdehyde + Phosphate + NAD+ -> NADH + H+ + L_Glutamyl_5_phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Potassium phosphate
PH: 6.5
Temperature: 30
uniprot:Q9HX20 [glutamate-5-semialdehyde dehydrogenase(Enzyme) wildtype]

NADP+ + L_Glutamate_5_semialdehyde + Phosphate -> L_Glutamyl_5_phosphate + H+ + NADPH		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Potassium phosphate
PH: 6.5
Temperature: 30
uniprot:Q9HX20 [glutamate-5-semialdehyde dehydrogenase(Enzyme) wildtype]

Phosphate + L_Glutamate_5_semialdehyde + NADP+ -> L_Glutamyl_5_phosphate + NADPH + H+		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Potassium phosphate
PH: 6.5
Temperature: 30
uniprot:Q9HX20 [glutamate-5-semialdehyde dehydrogenase(Enzyme) wildtype]

Phosphate + NADP+ + L_Glutamate_5_semialdehyde -> NADPH + L_Glutamyl_5_phosphate + H+		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Potassium phosphate
PH: 6.5
Temperature: 30
uniprot:Q9HX20 [glutamate-5-semialdehyde dehydrogenase(Enzyme) wildtype]

NAD+ + Phosphate + L_Glutamate_5_semialdehyde -> L_Glutamyl_5_phosphate + H+ + NADH		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Potassium phosphate
PH: 6.5
Temperature: 30

Pathways

pathway id name
BioCyc:HUMAN_PROSYN-PWY proline biosynthesis
BioCyc:META_PWY-5004 superpathway of L-citrulline metabolism
BioCyc:YEAST_CITRULBIO-PWY citrulline biosynthesis
BioCyc:ARA_ARGININE-SYN4-PWY L-ornithine biosynthesis II
BioCyc:ARA_CITRULBIO-PWY L-citrulline biosynthesis
BioCyc:ARA_PROSYN-PWY L-proline biosynthesis I
BioCyc:MTBH37RV_PROSYN-PWY L-proline biosynthesis I
BioCyc:ANTHRA_PWY-3341 L-proline biosynthesis III
BioCyc:BSUB_PROSYN-PWY L-proline biosynthesis I
BioCyc:SYNEL_PROSYN-PWY L-proline biosynthesis I
BioCyc:META_PWY-6922 L-Nδ-acetylornithine biosynthesis
BioCyc:ARA_PWY-3341 L-proline biosynthesis III
BioCyc:MTBCDC1551_PROSYN-PWY L-proline biosynthesis I
BioCyc:CAULO_PROSYN-PWY proline biosynthesis I
BioCyc:ANTHRA_PROSYN-PWY L-proline biosynthesis I
BioCyc:MOUSE_PWY-5004 superpathway of citrulline metabolism
BioCyc:ECOL316407_PROSYN-PWY proline biosynthesis I
BioCyc:CORYNE_PROSYN-PWY L-proline biosynthesis I
BioCyc:HUMAN_ARGININE-SYN4-PWY ornithine de novo biosynthesis
BioCyc:META_CITRULBIO-PWY L-citrulline biosynthesis
BioCyc:META_PWY-3341 L-proline biosynthesis III
BioCyc:ECO_PROSYN-PWY L-proline biosynthesis I
BioCyc:ECOL199310_PROSYN-PWY proline biosynthesis I
BioCyc:MOUSE_PROLINE-SYN2-PWY proline biosynthesis II
BioCyc:META_ARGININE-SYN4-PWY L-ornithine biosynthesis II
BioCyc:META_PROSYN-PWY L-proline biosynthesis I
BioCyc:YEAST_PROSYN-PWY proline biosynthesis
BioCyc:ARA_PWY-6922 L-Nδ-acetylornithine biosynthesis
BioCyc:MTBH37RV_PWY-3341 L-proline biosynthesis III
BioCyc:ECOO157_PROSYN-PWY proline biosynthesis I
BioCyc:MOUSE_CITRULBIO-PWY citrulline biosynthesis
BioCyc:BTHE_PROSYN-PWY proline biosynthesis I
PathBank:SMP0000815 Proline Metabolism
Plant Reactome:R-OSA-1119495 Citrulline biosynthesis
Plant Reactome:R-OSA-1119631 Proline biosynthesis I
Plant Reactome:R-OSA-2744345 Metabolism and regulation
Plant Reactome:R-OSA-2744343 Amino acid metabolism
Plant Reactome:R-OSA-5655122 Amino acid biosynthesis
PlantCyc:ARA_CITRULBIO-PWY L-citrulline biosynthesis
PlantCyc:ARA_PROUT-PWY L-proline degradation
PlantCyc:ARA_ARGASEDEG-PWY L-arginine degradation I (arginase pathway)
PlantCyc:ARA_PWY-3341 L-proline biosynthesis III
PlantCyc:ARA_PROSYN-PWY L-proline biosynthesis I
PlantCyc:ARA_ARGININE-SYN4-PWY L-ornithine biosynthesis II
PlantCyc:PLANT_ARGININE-SYN4-PWY L-ornithine biosynthesis II
PlantCyc:ARA_PWY-5004 superpathway of L-citrulline metabolism
PlantCyc:PLANT_PWY-5004 superpathway of L-citrulline metabolism
PlantCyc:PLANT_PWY-6922 L-Nδ-acetylornithine biosynthesis
PlantCyc:ARA_PWY-6922 L-Nδ-acetylornithine biosynthesis
PlantCyc:PLANT_PWY-3341 L-proline biosynthesis III
PlantCyc:PLANT_CITRULBIO-PWY L-citrulline biosynthesis
Reactome:R-SCE-8964539 Glutamate and glutamine metabolism
Reactome:R-CEL-8964539 Glutamate and glutamine metabolism
Reactome:R-SPO-8964539 Glutamate and glutamine metabolism
Reactome:R-MMU-8964539 Glutamate and glutamine metabolism
Reactome:R-MMU-1430728 Metabolism
Reactome:R-SCE-71291 Amino acid and derivative metabolism
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SPO-71291 Amino acid and derivative metabolism
Reactome:R-CEL-71291 Amino acid and derivative metabolism
Reactome:R-MMU-71291 Amino acid and derivative metabolism
Reactome:R-CEL-1430728 Metabolism
WikiPathways:WP497 Urea cycle and metabolism of amino groups
WikiPathways:WP5312 Metabolic pathways of fibroblasts
PathBank:SMP0121276 Proline Metabolism
PathBank:SMP0002297 Proline Metabolism