CYB561A3 - Homo sapiens

Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3

Alternative splicing Electron transport Endosome Glycoprotein Heme Iron Lysosome Membrane Metal-binding Oxidoreductase Proteomics identification Reference proteome Translocase Transmembrane Transmembrane helix Transport

Late endosome membrane Lysosome membrane
> CYB561A3 - Homo sapiens [Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3]
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统计信息
序列长度 0
疏水性残基 0
极性残基 0
Legend

Metadata

Organism Source: 9606 - Homo sapiens
EC Number: 7.2.1.3
Cluster:
Registry Model: CYB561A3, CYBASC3 - lysosomal membrane ascorbate-dependent ferrireductase [EC:7.2.1.3]

Functional Domains

domain start ends site
Cytoplasmic 1 7 MVSGRFY
Cytoplasmic 67 83 RLPQSWVGPKLPWKLLH
Cytoplasmic 141 154 LPWASMWLRSLLKP
Cytoplasmic 224 242 KRPEPGILTDRQPLLHDGE
Lumenal 29 45 QYWRGGFAWNGSIYMFN
Lumenal 105 119 HNHGRTANLYSLHSW
Lumenal 176 202 NEKLFFSLKNTTRPYHSLPSEAVFANS
Cytochrome b561 12 219 LLGSLGSMCILFTIYWMQYWRGGFAWNGSIYMFNWHPVLMVAGMVVFYGGASLVYRLPQSWVGPKLPWKLLHAALHLMAFVLTVVGLVAVFTFHNHGRTANLYSLHSWLGITTVFLFACQWFLGFAVFLLPWASMWLRSLLKPIHVFFGAAILSLSIASVISGINEKLFFSLKNTTRPYHSLPSEAVFANSTGMLVVAFGLLVLYILL

Reactions

reaction id name note
KEGG:R09739 Fe(III):ascorbate oxidorectuctase (electron-translocating) Ascorbate + Fe3+ <=> Monodehydroascorbate + Fe2+
Rhea:RHEA:30404 Fe3+(out) + L-ascorbate(in) => monodehydro-L-ascorbate radical(in) + Fe2+(out) + H+
Rhea:RHEA:30405 monodehydro-L-ascorbate radical(in) + Fe2+(out) + H+ => Fe3+(out) + L-ascorbate(in)
Rhea:RHEA:30406 Fe3+(out) + L-ascorbate(in) <=> monodehydro-L-ascorbate radical(in) + Fe2+(out) + H+
BioCyc:RXN-15598 ASCORBATE + FE+3 --> CPD-318 + FE+2

Pathways

pathway id name