Phosphatidylcholine Biosynthesis PC(14:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z))

Metabolites

ADP

Formula: C10H15N5O10P2 (427.02941500000003)

CAS ID: 58-64-0

ATP

Formula: C10H16N5O13P3 (506.9957476)

CAS ID: 56-65-5

CDP-ethanolamine

Formula: C11H20N4O11P2 (446.06037899999995)

CAS ID: 3036-18-8

Choline

Formula: C5H14NO (104.10753340000001)

CAS ID: 62-49-7

Choline phosphate

Formula: C5H15NO4P (184.07386599999998)

CAS ID: 107-73-3

CMP

Formula: C9H14N3O8P (323.05184940000004)

CAS ID: 63-37-6

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

CTP

Formula: C9H16N3O14P3 (482.9845146)

CAS ID: 65-47-4

Ethanolamine

Formula: C2H7NO (61.0527612)

CAS ID: 141-43-5

Ethanolamine phosphate

Formula: C2H8NO4P (141.0190938)

CAS ID: 1071-23-4

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

DG(14:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)

Formula: C37H60O5 (584.444051)

CAS ID:

PC(14:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z))

Formula: C42H72NO8P (749.4995282)

CAS ID:

PE(14:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z))

Formula: C39H66NO8P (707.4525806)

CAS ID:

Phosphatidylserine

Formula: C13H24NO10P (385.1137774)

CAS ID: 8002-43-5

PE-NMe(14:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z))

Formula: C40H68NO8P (721.4682298)

CAS ID:

PE-NMe2(14:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z))

Formula: C41H70NO8P (735.483879)

CAS ID:

diphosphate

Formula: O7P2 (173.911931)

CAS ID: 14000-31-8



Enzyme

EC Number name full name note
2.1.1.17 phosphatidylethanolamine N-methyltransferase S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase
2.1.1.71 phosphatidyl-N-methylethanolamine N-methyltransferase S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase
2.7.1.32 choline kinase ATP:choline phosphotransferase
2.7.1.82 ethanolamine kinase ATP:ethanolamine O-phosphotransferase
2.7.7.14 ethanolamine-phosphate cytidylyltransferase CTP:ethanolamine-phosphate cytidylyltransferase
2.7.7.15 choline-phosphate cytidylyltransferase CTP:choline-phosphate cytidylyltransferase
2.7.8.2 diacylglycerol cholinephosphotransferase CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase
4.1.1.65 phosphatidylserine decarboxylase phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming)


Pathway Source

Organism Taxonomy Group Enzyme List Source Ratio
Aspergillus niger CBS 513.88 MAGs 2.1.1.17 / 2.1.1.71 / 2.7.1.32 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 100.00%
Homo sapiens vertebrate_mammalian 2.1.1.17 / 2.1.1.71 / 2.7.1.32 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 100.00%
Saccharomyces cerevisiae S288C MAGs 2.1.1.17 / 2.1.1.71 / 2.7.1.32 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 100.00%
Rattus norvegicus vertebrate_mammalian 2.1.1.17 / 2.1.1.71 / 2.7.1.32 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 100.00%
Mus musculus vertebrate_mammalian 2.1.1.17 / 2.1.1.71 / 2.7.1.32 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 100.00%
Histoplasma capsulatum fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Aspergillus parasiticus MAGs 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Penicillium crustosum fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Trichophyton rubrum fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Exophiala dermatitidis fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Penicillium expansum fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Aspergillus flavus fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Penicillium griseofulvum fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Aspergillus niger fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Penicillium brevicompactum fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Penicillium citrinum fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Penicillium canescens fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Penicillium vulpinum fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Aspergillus tubingensis fungi 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%
Trichophyton violaceum MAGs 2.1.1.17 / 2.1.1.71 / 2.7.1.82 / 2.7.7.14 / 2.7.7.15 / 2.7.8.2 / 4.1.1.65 87.50%