Metabolite Card
Chinese Name: 2-脱氧腺苷-5-单磷酸
Formula: C10H14N5O6P (331.0682)
SMILES:
NC1=NC=NC2=C1N=CN2[C@H]1C[C@H](O)[C@@H](COP(O)(O)=O)O1Synonyms [en]
dAMP; 2'-Deoxyadenosine 5'-phosphate; deoxyadenosine monophosphate; 2'-deoxyadenosine-5'-monophosphate; 2'-Deoxyadenosine 5'-monophosphate; Deoxyadenylic acid
Last reviewed on 2026-04-16.
Cite this Page
dAMP. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/dAMP
(retrieved
2026-08-20) (CAD Registry RN: BioCAD00000009499). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Deoxyadenosine monophosphate (dAMP), also known as deoxyadenylic acid or deoxyadenylate in its conjugate acid and conjugate base forms, respectively, is a derivative of the common nucleic acid AMP, or adenosine monophosphate, in which the -OH (hydroxyl) group on the 2' carbon on the nucleotide's pentose has been reduced to just a hydrogen atom (hence the "deoxy-" part of the name). Additionally, the monophosphate of the name indicates that two of the phosphoryl groups of GTP have been removed, most likely by hydrolysis. It is a monomer used in DNA.
DBLinks
- CAS Registry Number: 653-63-4
- PubChem CID: 12599
- ChEBI: 17713
- HMDB: HMDB0000905
- LipidMaps:
- KEGG: C00360
- BioCyc: DAMP
- NCBI MeSH: 2'-deoxy-5'-adenosine monophosphate
- Wikipedia: Deoxyadenosine_monophosphate
Other DBLinks
- CAS Registry Number: 207127-57-9 (.H2O)
- CAS Registry Number: 54509-79-4
- CAS Registry Number: 653-63-4
- PubChem: 12599
- PubChem: 3651
- PubChem: 621
- ChEBI: ChEBI:17713
- HMDB: HMDB0000905
- KEGG: C00360
- BioCyc: DAMP
- NCBI MeSH: 2'-deoxy-5'-adenosine monophosphate
- Wikipedia: Deoxyadenosine_monophosphate
- RefMet: RM0156433
- MoNA: BAF_UVA_POS000160
- MoNA: BAF_UVA_POS000161
- MoNA: BAF_UVA_POS000878
- MoNA: BAF_UVA_POS000879
- MoNA: BAF_UVA_POS000880
- MoNA: BML80250
- MoNA: BML80251
- MoNA: CCMSLIB00000577915
- MoNA: CCMSLIB00000578148
- MoNA: CCMSLIB00005464504
- MoNA: CCMSLIB00005464505
- MoNA: CCMSLIB00005464538
- MoNA: CCMSLIB00005720358
- MoNA: EMBL-MCF_spec104275
- MoNA: EMBL-MCF_spec29219
- MoNA: EMBL_MCF_2_0_HRMS_Library000093
- MoNA: EMBL_MCF_2_0_HRMS_Library000349
- MoNA: FiehnHILIC000019
- MoNA: FiehnHILIC000891
- MoNA: FiehnHILIC001630
- MoNA: FiehnLib000198
- MoNA: HMDB0000905_ms_ms_1289
- MoNA: HMDB0000905_ms_ms_1290
- MoNA: HMDB0000905_ms_ms_1291
- MoNA: MoNA001687
- MoNA: MoNA002294
- MoNA: MoNA002295
- MoNA: MoNA002297
- MoNA: MoNA016689
- MoNA: MoNA024268
- MoNA: MoNA033642
- MoNA: MoNA033644
- MoNA: MoNA033647
- MoNA: MoNA034739
- MoNA: MoNA034740
- MoNA: MoNA034743
- MoNA: MoNA036428
- MoNA: MoNA036429
- MoNA: MoNA036431
- MoNA: MoNA037372
- MoNA: MoNA038123
- MoNA: MoNA038702
- MoNA: PR010127
- MoNA: PR100083
- MoNA: PR100084
- MoNA: PR100521
- MoNA: PS014201
- MoNA: PS014202
- MoNA: PS014203
- MoNA: PS014204
- MoNA: PS014205
- MoNA: PS014206
- MoNA: PS014207
- MoNA: PS014208
- MoNA: PT101420
- MoNA: PT101423
- MoNA: PT201420
- Metlin: METLIN_3461
- Coconut NaturalProduct: CNP0268176.1
- PMHub: MS000000885
- metaboanalyst: 077ec5dd5ed7c8c5a538953397e396ce
- metaboanalyst: 2c50cda7b5ede7c95e8304255ce46404
- metaboanalyst: 4c64e09bb6008591094ebbc2c39b767d
- metaboanalyst: f3bcc3ed2d31004af0b05cfa38727a2a
- metaboanalyst: f77484457f9bd6f9337121b3fdacdfe6
Class / Ontology
- WishartLab ClassyFire: [Purine deoxyribonucleotides] Purine deoxyribonucleotides
- RefMet: [Purine dNMP] Purine dNMP
- ChEBI: [CHEBI:17713] 2'-deoxyadenosine 5'-monophosphate
- Coconut NaturalProduct: [Purine nucleos(t)ides] Purine nucleos(t)ides
| ID | EC Number | Name |
|---|---|---|
| KEGG:R01547 | 2.7.4.3 | ATP:dAMP phosphotransferase |
| KEGG:R02088 | 3.1.3.5 | 2'-deoxyadenosine 5'-monophosphate phosphohydrolase |
| KEGG:R02089 | 2.7.1.76 | ATP:deoxyadenosine 5'-phosphotransferase |
| KEGG:R13374 | 5.3.99.13 | C22949 + C00360 + C00028<=>C22959 + C05198 + C00030 |
| KEGG:R13375 | 5.3.99.13 | dAMP isomerase (4'-phospho-dehydrooxetanocin-forming) |
| BioCyc:DEOXYADENOSINE-KINASE-RXN | 2.7.1.74 | DEOXYADENOSINE + ATP --> PROTON + DAMP + ADP |
| BioCyc:RXN-14161 | 3.1.3.89 | DAMP + WATER --> DEOXYADENOSINE + Pi |
| BioCyc:RXN0-384 | 3.6.1.- | DATP + WATER --> PROTON + DAMP + PPI |
| BioCyc:RXN-18739 | 1.14.11.33 | CPD-20035 + 2-KETOGLUTARATE + OXYGEN-MOLECULE --> DAMP + FORMALDEHYDE + SUC + CARBON-DIOXIDE |
| BioCyc:DEOXYADENYLATE-KINASE-RXN | 2.7.4.13 | ATP + DAMP --> ADP + DADP |
| BioCyc:RXN-14195 | 3.6.1.5 | DATP + 2 WATER --> DAMP + 2 Pi + 2 PROTON |
| BioCyc:RXN-14215 | DADP + WATER --> DAMP + Pi + PROTON | |
| BioCyc:RXN-14099 | 2.7.1.74 | DEOXYADENOSINE + UTP<=>PROTON + DAMP + UDP |
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| WikiPathways:WP2185 | Purine metabolism |
| WikiPathways:WP3604 | Biochemical pathways: part I |
| PathBank:SMP0120670 | Adenylosuccinate Lyase Deficiency |
| PathBank:SMP0120448 | Adenosine Deaminase Deficiency |
| PathBank:SMP0120452 | AICA-Ribosiduria |
| PathBank:SMP0120508 | Lesch-Nyhan Syndrome (LNS) |
| PathBank:SMP0120532 | Molybdenum Cofactor Deficiency |
| PathBank:SMP0120536 | Purine Nucleoside Phosphorylase Deficiency |
| PathBank:SMP0120577 | Xanthinuria Type I |
| PathBank:SMP0120601 | Mitochondrial DNA Depletion Syndrome |
| PathBank:SMP0000167 | Adenylosuccinate Lyase Deficiency |
| PathBank:SMP0000220 | Xanthine Dehydrogenase Deficiency (Xanthinuria) |
| PathBank:SMP0000512 | Xanthinuria Type I |
| PathBank:SMP0000536 | Mitochondrial DNA Depletion Syndrome-3 |
| PathBank:SMP0063668 | Purine Metabolism |
| PathBank:SMP0120669 | Adenosine Deaminase Deficiency |
| PathBank:SMP0120673 | AICA-Ribosiduria |
| PathBank:SMP0120709 | Gout or Kelley-Seegmiller Syndrome |
| PathBank:SMP0120717 | Xanthine Dehydrogenase Deficiency (Xanthinuria) |
| PathBank:SMP0120797 | Xanthinuria Type II |