EC: 4.1.1.36

phosphopantothenoylcysteine decarboxylase (N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming))

enzyme lambda metabolic reaction experiment
- [phosphopantothenoylcysteine decarboxylase(Enzyme) wildtype]

(R)_4'_Phosphopantothenoyl_L_cysteine -> 4'_Phosphopantetheine + CO2		 (( (Vmax * S) ) / (Km + S)) buffer: 40 mM Tris-HCl
PH: 8
Temperature: 37
- [phosphopantothenoylcysteine decarboxylase(Enzyme) wildtype]

(R)_4'_Phosphopantothenoyl_L_cysteine -> 4'_Phosphopantetheine + CO2		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 40 mM Tris, 4 mM cysteine
PH: 8
Temperature: 37
- [phosphopantothenoylcysteine decarboxylase(Enzyme) wildtype]

(R)_4'_Phosphopantothenoyl_L_cysteine -> 4'_Phosphopantetheine + CO2		 (( (Vmax * S) ) / (Km + S)) buffer: 40 mM Tris, 4 mM cysteine
PH: 8
Temperature: 37
uniprot:Q96CD2 [phosphopantothenoylcysteine decarboxylase(Enzyme) wildtype]

(R)_4'_Phosphopantothenoyl_L_cysteine -> 4'_Phosphopantetheine + CO2		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, pyrophosphate reagent, 2.0 mM ATP, 1.0 mM DTT, 10 mM MgCl2, 20 mM KCl, 1.5 µM 6 x His-ECCoaD
PH: 7.6
Temperature: 37

Pathways

pathway id name
BioCyc:META_PWY-7851 coenzyme A biosynthesis II (eukaryotic)
BioCyc:ECO_COA-PWY coenzyme A biosynthesis I (prokaryotic)
BioCyc:HUMAN_PWY-7851 coenzyme A biosynthesis II (eukaryotic)
BioCyc:ARA_COA-PWY coenzyme A biosynthesis I
BioCyc:VCHO_COA-PWY coenzyme A biosynthesis I (prokaryotic)
BioCyc:BSUB_COA-PWY coenzyme A biosynthesis I (prokaryotic)
BioCyc:ECOL316407_COA-PWY coenzyme A biosynthesis
BioCyc:HUMAN_COA-PWY-1 coenzyme A biosynthesis
BioCyc:META_PANTOSYN-PWY superpathway of coenzyme A biosynthesis I (bacteria)
BioCyc:META_COA-PWY-1 superpathway of coenzyme A biosynthesis III (mammals)
BioCyc:MTBCDC1551_PANTOSYN-PWY pantothenate and coenzyme A biosynthesis I
BioCyc:MOUSE_COA-PWY coenzyme A biosynthesis
BioCyc:META_COA-PWY coenzyme A biosynthesis I (prokaryotic)
BioCyc:ECO_PANTOSYN-PWY superpathway of coenzyme A biosynthesis I (bacteria)
BioCyc:ARA_PWY-4221ARA superpathway of pantothenate and coenzymeA biosynthesis
BioCyc:MTBCDC1551_COA-PWY coenzyme A biosynthesis
BioCyc:BSUB_PANTOSYN-PWY superpathway of coenzyme A biosynthesis I (bacteria)
BioCyc:ECOL316407_PANTOSYN-PWY pantothenate and coenzyme A biosynthesis I
PathBank:SMP0000848 Pantothenate and CoA Biosynthesis
PlantCyc:PLANT_COA-PWY coenzyme A biosynthesis I (prokaryotic)
PlantCyc:ARA_PWY-7851 coenzyme A biosynthesis II (eukaryotic)
PlantCyc:PLANT_PWY-4221 superpathway of coenzyme A biosynthesis II (plants)
PlantCyc:ARA_COA-PWY coenzyme A biosynthesis I (prokaryotic)
PlantCyc:ARA_PWY-4221ARA superpathway of pantothenate and coenzymeA biosynthesis
PlantCyc:ARA_PWY-4221 superpathway of coenzyme A biosynthesis II (plants)
PlantCyc:PLANT_PWY-7851 coenzyme A biosynthesis II (eukaryotic)
PlantCyc:PLANT_PWY-4221ARA superpathway of pantothenate and coenzymeA biosynthesis
Reactome:R-DDI-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-DDI-199220 Vitamin B5 (pantothenate) metabolism
Reactome:R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-HSA-199220 Vitamin B5 (pantothenate) metabolism
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-MMU-199220 Vitamin B5 (pantothenate) metabolism
Reactome:R-DDI-196854 Metabolism of vitamins and cofactors
Reactome:R-HSA-196854 Metabolism of vitamins and cofactors
Reactome:R-MMU-196854 Metabolism of vitamins and cofactors
Reactome:R-DDI-196783 Coenzyme A biosynthesis
Reactome:R-HSA-196783 Coenzyme A biosynthesis
Reactome:R-MMU-196783 Coenzyme A biosynthesis
Reactome:R-DDI-1430728 Metabolism
Reactome:R-HSA-1430728 Metabolism
PathBank:SMP0063647 Pantothenate and CoA Biosynthesis
PathBank:SMP0000027 Pantothenate and CoA Biosynthesis