EC: 3.5.1.24

choloylglycine hydrolase (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine amidohydrolase)

enzyme lambda metabolic reaction experiment
uniprot:P54965 [choloylglycine hydrolase(Enzyme) wildtype]

H2O + Glycocholate -> 3alpha,7alpha,12alpha_Trihydroxy_5beta_cholanate + Glycine
(( (Vmax * A) ) / (Km + A)) buffer: 500 mM Sodium phosphate, 1 mM EDTA
PH: 6
Temperature: 37

Pathways

pathway id name
BioCyc:META_PWY-6518 glycocholate metabolism (bacteria)
BioCyc:META_PWY-7754 bile acids degradation
WikiPathways:WP5176 Disorders of bile acid synthesis and biliary transport