EC: 2.6.1.7

kynurenine-oxoglutarate transaminase (L-kynurenine:2-oxoglutarate aminotransferase)

enzyme lambda metabolic reaction experiment
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Alanine + Glyoxylate -> Glycine + Pyruvate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + 2_Oxoglutarate -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

Glyoxylate + L_Leucine -> 4_Methyl_2_oxopentanoate + Glycine		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

3_Hydroxy_L_kynurenine + Glyoxylate -> Glycine + 4_(2_Amino_3_hydroxyphenyl)_2,4_dioxobutanoate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + 4_Methylthio_2_oxobutanoate -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + Unknown		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + Phenylpyruvate -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + Unknown		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

Aminobutyrate + Glyoxylate -> Succinate_semialdehyde + Glycine		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + 2_Oxohexanoate -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + Unknown		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Glutamate + Glyoxylate -> Glycine + 2_Oxoglutarate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

Glyoxylate + L_Tyrosine -> 3_(4_Hydroxyphenyl)pyruvate + Glycine		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + Glyoxylate -> Glycine + 4_(2_Aminophenyl)_2,4_dioxobutanoate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

Glyoxylate + L_Tryptophan -> Indolepyruvate + Glycine		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

Pyruvate + L_Kynurenine -> L_Alanine + 4_Hydroxy_2_quinolinecarboxylic_acid		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

Glyoxylate + L_Phenylalanine -> Glycine + Phenylpyruvate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + 3_Methyl_2_oxopentanoate -> Unknown + 4_(2_Aminophenyl)_2,4_dioxobutanoate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

2_Oxovaline + L_Kynurenine -> Unknown + 4_(2_Aminophenyl)_2,4_dioxobutanoate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + Oxaloacetate -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + L_Aspartate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + Glyoxylate -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + Glycine		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + 2_Oxobutyrate -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + Unknown		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + Indolepyruvate -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + Unknown		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

2_Oxopentanoate + L_Kynurenine -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + Unknown		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + 3_Mercaptopyruvate -> Unknown + 4_(2_Aminophenyl)_2,4_dioxobutanoate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + Hydroxyphenylpyruvate -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + Unknown		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

L_Kynurenine + 2_Oxoadipate -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + Unknown		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q8N5Z0 [Pyridoxal phosphate]

2_Oxoleucine + L_Kynurenine -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + Unknown		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:Q08415 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

L_Kynurenine + 2_Oxoglutarate -> 4_Hydroxy_2_quinolinecarboxylic_acid + L_Glutamate		 (( (Vmax * S) ) / (Km + S)) buffer: 70 µM pyridoxal 5'-phosphate, 150 mM Tris-acetate
PH: 8
Temperature: 37
uniprot:Q08415 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

2_Oxoglutarate + L_Kynurenine -> L_Glutamate + 4_Hydroxy_2_quinolinecarboxylic_acid		 (( (Vmax * S) ) / (Km + S)) buffer: 70 µM pyridoxal 5'-phosphate, 150 mM Tris-acetate
PH: 8
Temperature: 37
uniprot:Q08415 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

Pyruvate + L_Kynurenine -> 4_Hydroxy_2_quinolinecarboxylic_acid + L_Alanine		 (( (Vmax * S) ) / (Km + S)) buffer: 70 µM pyridoxal 5'-phosphate, 150 mM Tris-acetate
PH: 8
Temperature: 37
uniprot:Q08415 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

L_Kynurenine + Pyruvate -> 4_Hydroxy_2_quinolinecarboxylic_acid + L_Alanine		 (( (Vmax * S) ) / (Km + S)) buffer: 70 µM pyridoxal 5'-phosphate, 150 mM Tris-acetate
PH: 8
Temperature: 37
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

L_Kynurenine + 2_Oxoglutarate -> L_Glutamate + 4_(2_Aminophenyl)_2,4_dioxobutanoate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

Cysteine + 2_Oxobutyrate -> Ketoacid + Aminobutyrate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

Tyrosine + 2_Oxobutyrate -> Ketoacid + Aminobutyrate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

Tryptophan + 2_Oxobutyrate -> Aminobutyrate + Ketoacid		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

2_Oxobutyrate + Serine -> Aminobutyrate + Ketoacid		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

Histidine + 2_Oxobutyrate -> Aminobutyrate + Ketoacid		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

Glutamine + 2_Oxobutyrate -> Ketoacid + Aminobutyrate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

2_Oxobutyrate + Phenylalanine -> Aminobutyrate + Ketoacid		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

Methionine + 2_Oxobutyrate -> Ketoacid + Aminobutyrate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

Leucine + 2_Oxobutyrate -> Aminobutyrate + Ketoacid		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

Asparagine + 2_Oxobutyrate -> Ketoacid + Aminobutyrate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

Alanine + 2_Oxobutyrate -> Aminobutyrate + Pyruvate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q95VY4 [kynurenine---oxoglutarate transaminase(Enzyme) wildtype]

Aminobutyrate + Pyruvate -> 2_Oxobutyrate + Alanine		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris, 40 µM pyridoxal 5'-phosphate
PH: 8.5
Temperature: 45
uniprot:Q64602 [Pyridoxal phosphate]

3_Hydroxykynurenine + 2_Oxoglutarate -> L_Glutamate + 4_(2_Amino_3_hydroxyphenyl)_2,4_dioxobutanoate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

3_Hydroxykynurenine + 2_Oxoglutarate -> L_Glutamate + 4_(2_Amino_3_hydroxyphenyl)_2,4_dioxobutanoate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

2_Oxoglutarate + 3_Hydroxykynurenine -> 4_(2_Amino_3_hydroxyphenyl)_2,4_dioxobutanoate + L_Glutamate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

2_Oxoglutarate + 3_Hydroxykynurenine -> L_Glutamate + 4_(2_Amino_3_hydroxyphenyl)_2,4_dioxobutanoate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

3_Hydroxykynurenine + 2_Oxoglutarate -> 4_(2_Amino_3_hydroxyphenyl)_2,4_dioxobutanoate + L_Glutamate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

2_Oxoglutarate + 3_Hydroxykynurenine -> 4_(2_Amino_3_hydroxyphenyl)_2,4_dioxobutanoate + L_Glutamate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

L_Kynurenine + Oxaloacetate -> L_Aspartate + 4_(2_Aminophenyl)_2,4_dioxobutanoate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

2_Oxoadipate + L_Kynurenine -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + L_2_Aminoadipate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

3_Hydroxykynurenine + 2_Oxoadipate -> 4_(2_Amino_3_hydroxyphenyl)_2,4_dioxobutanoate + L_2_Aminoadipate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

3_Hydroxykynurenine + Oxaloacetate -> 4_(2_Amino_3_hydroxyphenyl)_2,4_dioxobutanoate + L_Aspartate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

L_Kynurenine + 2_Oxoglutarate -> L_Glutamate + 4_(2_Aminophenyl)_2,4_dioxobutanoate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

2_Oxoglutarate + L_Kynurenine -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + L_Glutamate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

L_Kynurenine + 2_Oxoglutarate -> L_Glutamate + 4_(2_Aminophenyl)_2,4_dioxobutanoate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

L_Kynurenine + 2_Oxoglutarate -> L_Glutamate + 4_(2_Aminophenyl)_2,4_dioxobutanoate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

2_Oxoglutarate + L_Kynurenine -> 4_(2_Aminophenyl)_2,4_dioxobutanoate + L_Glutamate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37
uniprot:Q64602 [Pyridoxal phosphate]

2_Oxoglutarate + L_Kynurenine -> L_Glutamate + 4_(2_Aminophenyl)_2,4_dioxobutanoate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM imidazole-HCl
PH: 6.5
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_PWY-4361 S-methyl-5-thio-α-D-ribose 1-phosphate degradation
BioCyc:HUMAN_PWY66-425 lysine degradation II (pipecolate pathway)
BioCyc:META_LYSINE-DEG1-PWY L-lysine degradation XI (mammalian)
BioCyc:META_PWY-7527 L-methionine salvage cycle III
BioCyc:META_HYDROXYPRODEG-PWY trans-4-hydroxy-L-proline degradation I
BioCyc:META_PWY-3502 superpathway of NAD biosynthesis in eukaryotes
BioCyc:HUMAN_LYSINE-DEG1-PWY lysine degradation I (saccharopine pathway)
BioCyc:META_PWY-5651 L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
BioCyc:META_PWY-5754 4-hydroxybenzoate biosynthesis I (eukaryotes)
BioCyc:META_PWY-5079 L-phenylalanine degradation III
BioCyc:YEAST_PWY-5082 L-methionine degradation III
BioCyc:YEAST_PWY3O-4108 tyrosine degradation
BioCyc:YEAST_PWY-5651 tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
BioCyc:MOUSE_GLUTFUMARATE-PWY glutamine degradation II
BioCyc:MOUSE_GLUTOXA-PWY glutamate degradation VII
BioCyc:MOUSE_LYSINE-DEG1-PWY lysine degradation II
BioCyc:HUMAN_PWY-7527 methionine salvage cycle III
BioCyc:HUMAN_PWY-6309 L-kynurenine degradation
BioCyc:HUMAN_HYDROXYPRODEG-PWY 4-hydroxyproline degradation
BioCyc:META_TYRSYN L-tyrosine biosynthesis I
BioCyc:META_PWY-5327 superpathway of L-lysine degradation
BioCyc:META_PWY3O-4108 L-tyrosine degradation III
BioCyc:META_PWY-4361 S-methyl-5-thio-α-D-ribose 1-phosphate degradation I
BioCyc:META_NADSYN-PWY NAD de novo biosynthesis II (from tryptophan)
BioCyc:YEAST_COMPLETE-ARO-YEAST-PWY superpathway of phenylalanine, tyrosine and tryptophan biosynthesis
BioCyc:YEAST_PWY3O-4120 tyrosine biosynthesis
BioCyc:YEAST_NADSYN-PWY NAD de novo biosynthesis
BioCyc:YEAST_PWY-5081 tryptophan degradation VIII (to tryptophol)
BioCyc:YEAST_PWY-5079 phenylalanine degradation
BioCyc:MOUSE_MALATE-ASPARTATE-SHUTTLE-PWY aspartate degradation II
BioCyc:MOUSE_ASPBIO-PWY aspartate biosynthesis
BioCyc:META_PWY-5081 L-tryptophan degradation VIII (to tryptophol)
BioCyc:META_PWY66-425 L-lysine degradation II (L-pipecolate pathway)
BioCyc:META_PWY-6318 L-phenylalanine degradation IV (mammalian, via side chain)
BioCyc:META_TRYPTOPHAN-DEGRADATION-1 L-tryptophan degradation III (eukaryotic)
BioCyc:META_PWY-6309 L-tryptophan degradation XI (mammalian, via kynurenine)
BioCyc:META_PWY-5082 L-methionine degradation III
Reactome:R-SSC-8964539 Glutamate and glutamine metabolism
Reactome:R-RNO-8964539 Glutamate and glutamine metabolism
Reactome:R-SCE-8964539 Glutamate and glutamine metabolism
Reactome:R-HSA-8963691 Phenylalanine and tyrosine metabolism
Reactome:R-SSC-8963693 Aspartate and asparagine metabolism
Reactome:R-RNO-8963693 Aspartate and asparagine metabolism
Reactome:R-RNO-8964208 Phenylalanine metabolism
Reactome:R-DDI-8964539 Glutamate and glutamine metabolism
Reactome:R-SCE-8964208 Phenylalanine metabolism
Reactome:R-MMU-8964539 Glutamate and glutamine metabolism
Reactome:R-RNO-8963691 Phenylalanine and tyrosine metabolism
Reactome:R-DDI-8963693 Aspartate and asparagine metabolism
Reactome:R-DDI-8964208 Phenylalanine metabolism
Reactome:R-SCE-8963691 Phenylalanine and tyrosine metabolism
Reactome:R-MMU-8963693 Aspartate and asparagine metabolism
Reactome:R-MMU-8964208 Phenylalanine metabolism
Reactome:R-HSA-8964539 Glutamate and glutamine metabolism
Reactome:R-DDI-8963691 Phenylalanine and tyrosine metabolism
Reactome:R-MMU-8963691 Phenylalanine and tyrosine metabolism
Reactome:R-HSA-8963693 Aspartate and asparagine metabolism
Reactome:R-HSA-8964208 Phenylalanine metabolism
Reactome:R-SSC-9856872 Malate-aspartate shuttle
Reactome:R-HSA-9856872 Malate-aspartate shuttle
Reactome:R-DDI-9856872 Malate-aspartate shuttle
Reactome:R-MMU-9856872 Malate-aspartate shuttle
Reactome:R-RNO-9856872 Malate-aspartate shuttle
Reactome:R-GGA-1660598 Metabolism
Reactome:R-GGA-352875 Gluconeogenesis
Reactome:R-HSA-611105 Respiratory electron transport
Reactome:R-HSA-71064 Lysine catabolism
Reactome:R-HSA-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-HSA-1614558 Degradation of cysteine and homocysteine
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-611105 Respiratory electron transport
Reactome:R-MMU-71064 Lysine catabolism
Reactome:R-MMU-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-RNO-611105 Respiratory electron transport
Reactome:R-RNO-71064 Lysine catabolism
Reactome:R-RNO-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-SCE-71291 Amino acid and derivative metabolism
Reactome:R-SSC-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-DDI-71291 Amino acid and derivative metabolism
Reactome:R-DDI-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-HSA-71240 Tryptophan catabolism
Reactome:R-MMU-71240 Tryptophan catabolism
Reactome:R-RNO-71240 Tryptophan catabolism
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SSC-1430728 Metabolism
Reactome:R-DDI-611105 Respiratory electron transport
Reactome:R-DDI-71240 Tryptophan catabolism
Reactome:R-GGA-353098 Carbohydrate metabolism
Reactome:R-GGA-372568 Amino acid metabolism
Reactome:R-HSA-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-HSA-71291 Amino acid and derivative metabolism
Reactome:R-MMU-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-MMU-71291 Amino acid and derivative metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-RNO-71291 Amino acid and derivative metabolism
Reactome:R-SSC-611105 Respiratory electron transport
Reactome:R-SSC-71291 Amino acid and derivative metabolism
Reactome:R-DDI-1430728 Metabolism
Reactome:R-DDI-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-1614635 Sulfur amino acid metabolism
Reactome:R-SCE-71240 Tryptophan catabolism
Reactome:R-SSC-1428517 Aerobic respiration and respiratory electron transport
WikiPathways:WP4595 Urea cycle and associated pathways
WikiPathways:WP5166 Glyoxylate metabolism
WikiPathways:WP465 Tryptophan metabolism
WikiPathways:WP5355 Metabolic Epileptic Disorders
WikiPathways:WP5044 Kynurenine pathway and links to cell senescence
WikiPathways:WP5220 Metabolic reprogramming in pancreatic cancer
PathBank:SMP0120746 Saccharopinuria/Hyperlysinemia II
PathBank:SMP0120854 Pyridoxine Dependency with Seizures
PathBank:SMP0120870 2-Aminoadipic 2-Oxoadipic Aciduria
PathBank:SMP0120456 Argininosuccinic Aciduria
PathBank:SMP0120496 Hyperinsulinism-Hyperammonemia Syndrome
PathBank:SMP0000059 Urea Cycle
PathBank:SMP0000129 Malate-Aspartate Shuttle
PathBank:SMP0000339 Hyperinsulinism-Hyperammonemia Syndrome
PathBank:SMP0000239 Saccharopinuria/Hyperlysinemia II
PathBank:SMP0000001 Citrullinemia Type I
PathBank:SMP0000528 Hyperlysinemia II or Saccharopinuria
PathBank:SMP0002353 Tryptophan Metabolism
PathBank:SMP0087330 Tryptophan Metabolism
PathBank:SMP0108760 Glutaminolysis and Cancer
PathBank:SMP0120455 Argininemia
PathBank:SMP0000385 Homocarnosinosis
PathBank:SMP0000186 Glutaric Aciduria Type I
PathBank:SMP0000003 Argininosuccinic Aciduria
PathBank:SMP0000136 2-Hydroxyglutric Aciduria (D and L Form)
PathBank:SMP0000527 Hyperlysinemia I, Familial
PathBank:SMP0000567 Succinic Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0000571 Pyridoxine Dependency with Seizures
PathBank:SMP0002301 L-Alanine Metabolism
PathBank:SMP0002352 Tyrosine Metabolism
PathBank:SMP0120704 Glutaric Aciduria Type I
PathBank:SMP0120812 Hyperlysinemia II or Saccharopinuria
PathBank:SMP0120445 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0000063 Tryptophan Metabolism
PathBank:SMP0000205 Ornithine Transcarbamylase Deficiency (OTC Deficiency)
PathBank:SMP0000719 2-Aminoadipic 2-Oxoadipic Aciduria
PathBank:SMP0087300 Lysine Degradation
PathBank:SMP0063590 Glutamate Metabolism
PathBank:SMP0063636 Malate-Aspartate Shuttle
PathBank:SMP0120811 Hyperlysinemia I, Familial
PathBank:SMP0120438 2-Hydroxyglutric Aciduria (D and L Form)
PathBank:SMP0120462 Carbamoyl Phosphate Synthetase Deficiency
PathBank:SMP0120466 Citrullinemia Type I
PathBank:SMP0120494 Homocarnosinosis
PathBank:SMP0120542 Ornithine Transcarbamylase Deficiency (OTC Deficiency)
PathBank:SMP0120631 Succinic Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0000072 Glutamate Metabolism
PathBank:SMP0000037 Lysine Degradation
PathBank:SMP0000243 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0000357 Argininemia
PathBank:SMP0000002 Carbamoyl Phosphate Synthetase Deficiency
PathBank:SMP0002298 Glutaminolysis and Cancer
PathBank:SMP0002310 Methionine Metabolism and Salvage
PathBank:SMP0002349 Phenylalanine Metabolism
PathBank:SMP0063686 Urea Cycle