EC: 2.6.1.4

glycine transaminase (glycine:2-oxoglutarate aminotransferase)

enzyme lambda metabolic reaction experiment
uniprot:Q9LR30 [glycine transaminase(Enzyme) wildtype GGT1]

L_Glutamate + Glyoxylate -> Glycine + 2_Oxoglutarate		 (( (Vmax * A) ) / (Km + A)) buffer: 60 mM potassium phosphate, 0.17 mM NADH, 2.2 units/ml bovine liver glutamic dehydrogenase
PH: 7.5
Temperature: 25
uniprot:Q9LR30 [glycine transaminase(Enzyme) wildtype GGT1]

Glyoxylate + L_Glutamate -> 2_Oxoglutarate + Glycine		 (( (Vmax * A) ) / (Km + A)) buffer: 60 mM potassium phosphate, 0.17 mM NADH, 2.2 units/ml bovine liver glutamic dehydrogenase
PH: 7.5
Temperature: 25
- [glycine transaminase(Enzyme) wildtype GGT]

L_Glutamate + Glyoxylate -> Glycine + 2_Oxoglutarate		 (( (Vmax * A) ) / (Km + A)) buffer: 60 mM potassium phosphate, 0.17 mM NADH, 2.2 units/ml bovine liver glutamic dehydrogenase
PH: 7.5
Temperature: 25
- [glycine transaminase(Enzyme) wildtype GGT]

Glyoxylate + L_Glutamate -> 2_Oxoglutarate + Glycine		 (( (Vmax * A) ) / (Km + A)) buffer: 60 mM potassium phosphate, 0.17 mM NADH, 2.2 units/ml bovine liver glutamic dehydrogenase
PH: 7.5
Temperature: 25
uniprot:Q9S7E9 [glycine transaminase(Enzyme) wildtype GGT2]

L_Glutamate + Glyoxylate -> Glycine + 2_Oxoglutarate		 (( (Vmax * A) ) / (Km + A)) buffer: 60 mM potassium phosphate, 0.17 mM NADH, 2.2 units/ml bovine liver glutamic dehydrogenase
PH: 7.5
Temperature: 25
uniprot:Q9S7E9 [glycine transaminase(Enzyme) wildtype GGT2]

Glyoxylate + L_Glutamate -> 2_Oxoglutarate + Glycine		 (( (Vmax * A) ) / (Km + A)) buffer: 60 mM potassium phosphate, 0.17 mM NADH, 2.2 units/ml bovine liver glutamic dehydrogenase
PH: 7.5
Temperature: 25

Pathways

pathway id name
BioCyc:HUMAN_PWY66-425 lysine degradation II (pipecolate pathway)
BioCyc:META_LYSINE-DEG1-PWY L-lysine degradation XI (mammalian)
BioCyc:HUMAN_LYSINE-DEG1-PWY lysine degradation I (saccharopine pathway)
BioCyc:META_PWY-181 photorespiration
BioCyc:MOUSE_LYSINE-DEG1-PWY lysine degradation II
BioCyc:HUMAN_PWY-6309 L-kynurenine degradation
BioCyc:META_PWY-5327 superpathway of L-lysine degradation
BioCyc:META_PWY66-425 L-lysine degradation II (L-pipecolate pathway)
BioCyc:META_PWY-6309 L-tryptophan degradation XI (mammalian, via kynurenine)
PlantCyc:ARA_GLYSYN-ALA-PWY glycine biosynthesis III
PlantCyc:ARA_GLYSYN2-PWY glycine biosynthesis
PlantCyc:PLANT_ALANINE-DEG3-PWY L-alanine degradation III
PlantCyc:PLANT_ALANINE-SYN2-PWY L-alanine biosynthesis II
PlantCyc:ARA_PWY-181 photorespiration
PlantCyc:ARA_ALANINE-SYN2-PWY L-alanine biosynthesis II
PlantCyc:ARA_ALANINE-DEG3-PWY L-alanine degradation III
PlantCyc:PLANT_PWY-181 photorespiration
PlantCyc:ARA_ALACAT2-PWY L-alanine degradation II (to D-lactate)
PlantCyc:PLANT_GLYSYN2-PWY glycine biosynthesis
Reactome:R-HSA-71064 Lysine catabolism
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-71064 Lysine catabolism
Reactome:R-RNO-71064 Lysine catabolism
Reactome:R-HSA-71240 Tryptophan catabolism
Reactome:R-MMU-71240 Tryptophan catabolism
Reactome:R-RNO-71240 Tryptophan catabolism
Reactome:R-HSA-71291 Amino acid and derivative metabolism
Reactome:R-MMU-71291 Amino acid and derivative metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-71291 Amino acid and derivative metabolism
Reactome:R-HSA-1430728 Metabolism
WikiPathways:WP465 Tryptophan metabolism
WikiPathways:WP5355 Metabolic Epileptic Disorders
WikiPathways:WP5044 Kynurenine pathway and links to cell senescence
PathBank:SMP0120746 Saccharopinuria/Hyperlysinemia II
PathBank:SMP0120854 Pyridoxine Dependency with Seizures
PathBank:SMP0120870 2-Aminoadipic 2-Oxoadipic Aciduria
PathBank:SMP0000239 Saccharopinuria/Hyperlysinemia II
PathBank:SMP0000528 Hyperlysinemia II or Saccharopinuria
PathBank:SMP0087330 Tryptophan Metabolism
PathBank:SMP0000186 Glutaric Aciduria Type I
PathBank:SMP0000527 Hyperlysinemia I, Familial
PathBank:SMP0000571 Pyridoxine Dependency with Seizures
PathBank:SMP0120704 Glutaric Aciduria Type I
PathBank:SMP0120812 Hyperlysinemia II or Saccharopinuria
PathBank:SMP0000063 Tryptophan Metabolism
PathBank:SMP0000719 2-Aminoadipic 2-Oxoadipic Aciduria
PathBank:SMP0087300 Lysine Degradation
PathBank:SMP0120811 Hyperlysinemia I, Familial
PathBank:SMP0000037 Lysine Degradation
PathBank:SMP0002415 Alanine Metabolism