EC: 2.6.1.36

L-lysine 6-transaminase (L-lysine:2-oxoglutarate 6-aminotransferase)

enzyme lambda metabolic reaction experiment
uniprot:Q93ZN9 [L-lysine 6-transaminase(Enzyme) wildtype His6-AGD2]

L_Lysine + 2_Oxoglutarate -> L_Glutamate + L_2_Aminoadipate_6_semialdehyde		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Tris/HCl, 100 mM MgCl2, 1 µM pyridoxal-5-phosphate
PH: 8
Temperature: 37
uniprot:Q9ZQI7 [L-lysine 6-transaminase(Enzyme) wildtype His6-ALD1]

2_Oxoglutarate + L_Lysine -> L_2_Aminoadipate_6_semialdehyde + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Tris/HCl, 100 mM MgCl2, 1 µM pyridoxal-5-phosphate
PH: 8
Temperature: 37
uniprot:Q93ZN9 [L-lysine 6-transaminase(Enzyme) wildtype His6-AGD2]

L_Lysine + 2_Oxoglutarate -> L_2_Aminoadipate_6_semialdehyde + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Tris/HCl, 100 mM MgCl2, 1 µM pyridoxal-5-phosphate
PH: 8
Temperature: 37
uniprot:Q93ZN9 [L-lysine 6-transaminase(Enzyme) mutant His6-AGD2 P398S]

L_Lysine + 2_Oxoglutarate -> L_2_Aminoadipate_6_semialdehyde + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Tris/HCl, 100 mM MgCl2, 1 µM pyridoxal-5-phosphate
PH: 8
Temperature: 37
uniprot:Q9ZQI7 [L-lysine 6-transaminase(Enzyme) wildtype His6-ALD1]

2_Oxoglutarate + L_Lysine -> L_2_Aminoadipate_6_semialdehyde + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Tris/HCl, 100 mM MgCl2, 1 µM pyridoxal-5-phosphate
PH: 8
Temperature: 37
uniprot:Q93ZN9 [L-lysine 6-transaminase(Enzyme) mutant His6-AGD2 P398S]

2_Oxoglutarate + L_Lysine -> L_2_Aminoadipate_6_semialdehyde + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Tris/HCl, 100 mM MgCl2, 1 µM pyridoxal-5-phosphate
PH: 8
Temperature: 37

Pathways

pathway id name
BioCyc:META_PWY-5327 superpathway of L-lysine degradation
BioCyc:META_PWY-5298 L-lysine degradation VI
BioCyc:MTBCDC1551_PWY-5298 L-lysine degradation VI