EC: 2.4.2.7

adenine phosphoribosyltransferase (AMP:diphosphate phospho-D-ribosyltransferase)

enzyme lambda metabolic reaction experiment
uniprot:P36972 [adenine phosphoribosyltransferase(Enzyme) wildtype]

Adenine + 5_Phospho_alpha_D_ribose_1_diphosphate -> AMP + Diphosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 10 mM MgCl2, 1 mM K-EDTA, 5 mg/ml BSA
PH: 7.4
Temperature: 37
uniprot:P36972 [adenine phosphoribosyltransferase(Enzyme) wildtype]

Adenine + 5_Phospho_alpha_D_ribose_1_diphosphate -> AMP + Diphosphate		 (( (Vmax * S) ) / (Km + S)) buffer: BM42B medium
PH: 7
Temperature: 37
uniprot:Q6MTD4 [adenine phosphoribosyltransferase(Enzyme) wildtype]

Adenine + 5_Phospho_alpha_D_ribose_1_diphosphate -> AMP + Diphosphate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 40 mM Tris-hydrochloride, 5 mM MgCl2, 0.2 mg/ml bovine serum albumin
PH: 8.15
Temperature: 37
uniprot:Q6MTD4 [adenine phosphoribosyltransferase(Enzyme) wildtype]

Adenine + 5_Phospho_alpha_D_ribose_1_diphosphate -> AMP + Diphosphate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 40 mM Tris-hydrochloride, 5 mM MgCl2, 0.2 mg/ml bovine serum albumin
PH: 7.7
Temperature: 37
uniprot:Q6MTD4 [adenine phosphoribosyltransferase(Enzyme) wildtype]

Adenine + 5_Phospho_alpha_D_ribose_1_diphosphate -> Diphosphate + AMP		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 40 mM HEPES, 5 mM MgCl2, 0.2 mg/ml bovine serum albumin
PH: 7
Temperature: 37
uniprot:Q43199 [Mg2+]

5_Phospho_alpha_D_ribose_1_diphosphate + Adenine -> AMP + Diphosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM beta-mercaptoethanol
PH: 7.5
Temperature: 37
uniprot:Q43199 [Mg2+]

5_Phospho_alpha_D_ribose_1_diphosphate + N6_(delta2_Isopentenyl)_adenine -> Diphosphate + N6_(delta2_Isopentenyl)_adenosine_5'_monophosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM beta-mercaptoethanol
PH: 7.5
Temperature: 37
uniprot:Q43199 [Mg2+]

Kinetin + 5_Phospho_alpha_D_ribose_1_diphosphate -> N6_furfuryladenosine_5'_phosphate + Diphosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM beta-mercaptoethanol
PH: 7.5
Temperature: 37
uniprot:Q43199 [Mg2+]

Adenine + 5_Phospho_alpha_D_ribose_1_diphosphate -> AMP + Diphosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM beta-mercaptoethanol
PH: 7.5
Temperature: 37
uniprot:Q43199 [Mg2+]

5_Phospho_alpha_D_ribose_1_diphosphate + 6_Benzylaminopurine -> Diphosphate + 6_Benzylaminopurine_riboside_monophosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM beta-mercaptoethanol
PH: 7.5
Temperature: 37
uniprot:P07741 [adenine phosphoribosyltransferase(Enzyme) wildtype]

5_Phospho_alpha_D_ribose_1_diphosphate + Adenine -> Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 5 mM MgCl2
PH: 7.4
Temperature: 37
uniprot:P07741 [adenine phosphoribosyltransferase(Enzyme) wildtype]

Adenine + 5_Phospho_alpha_D_ribose_1_diphosphate -> Diphosphate + AMP		 (( (Vmax * B) ) / (Km + B)) buffer: 50 mM Tris-HCl, 5 mM MgCl2
PH: 7.4
Temperature: 37

Pathways

pathway id name
BioCyc:META_PWY-6605 adenine and adenosine salvage II
BioCyc:ANTHRA_PWY-6610 adenine salvage
BioCyc:AGRO_P121-PWY adenine and adenosine salvage I
BioCyc:MOUSE_P121-PWY adenine and adenosine salvage I
BioCyc:BSUB_PWY-6610 adenine salvage
BioCyc:HUMAN_P121-PWY adenine and adenosine salvage I
BioCyc:HUMAN_PWY66-409 superpathway of purine nucleotide salvage
BioCyc:MTBH37RV_P121-PWY adenine and adenosine salvage I
BioCyc:ECOO157_PWY-6610 adenine and adenosine salvage IV
BioCyc:AGRO_PWY-6610 adenine salvage
BioCyc:MOUSE_P1-PWY purine and pyrimidine metabolism
BioCyc:BSUB_P1-PWY purine and pyrimidine metabolism
BioCyc:PDIF272563_P121-PWY adenine and adenosine salvage I
BioCyc:PDIF272563_PWY-6605 adenine and adenosine salvage II
BioCyc:BTHE_P121-PWY adenine and adenosine salvage I
BioCyc:META_PWY-7805 (aminomethyl)phosphonate degradation
BioCyc:META_PWY-6610 adenine salvage
BioCyc:META_PWY-7807 glyphosate degradation III
BioCyc:YEAST_PWY-6610 adenine and adenosine salvage IV
BioCyc:YEAST_PWY3O-2220 salvage pathways of adenine, hypoxanthine and their nucleosides
BioCyc:YEAST_PWY3O-1 superpathway of purine nucleosides salvage
BioCyc:ARA_PWY-5043 purine nucleosides salvage II (plant)
BioCyc:MTBH37RV_PWY-6605 adenine and adenosine salvage II
BioCyc:BTHE_PWY-6605 adenine and adenosine salvage II
BioCyc:CORYNE_P121-PWY adenine and adenosine salvage I
BioCyc:ECO_PWY-6605 adenine and adenosine salvage II
BioCyc:ECO_PWY-7805 (aminomethyl)phosphonate degradation
BioCyc:ARA_PWY-6605 adenine and adenosine salvage II
BioCyc:VCHO_P121-PWY adenine and adenosine salvage I
BioCyc:MTBCDC1551_P121-PWY adenine and adenosine salvage I
BioCyc:ECOO157_P121-PWY adenine and adenosine salvage I
BioCyc:ECOL316407_PWY-6605 adenine and adenosine salvage II
BioCyc:GCF_000013425_P121-PWY adenine and adenosine salvage I
PathBank:SMP0002084 Adenine and Adenosine Salvage III
PlantCyc:ARA_PWY-6605 adenine and adenosine salvage II
PlantCyc:ARA_PWY-5043 purine nucleosides salvage II (plant)
PlantCyc:PLANT_PWY-5043 purine nucleosides salvage II (plant)
Reactome:R-HSA-9734207 Nucleotide salvage defects
Reactome:R-HSA-9735804 Diseases of nucleotide metabolism
Reactome:R-HSA-9734195 Defective APRT disrupts adenine salvage
Reactome:R-HSA-74217 Purine salvage
Reactome:R-HSA-1643685 Disease
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-74217 Purine salvage
Reactome:R-RNO-74217 Purine salvage
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-15869 Nucleotide metabolism
Reactome:R-CEL-74217 Purine salvage
Reactome:R-DME-1430728 Metabolism
Reactome:R-DME-74217 Purine salvage
Reactome:R-HSA-8956321 Nucleotide salvage
Reactome:R-MMU-8956321 Nucleotide salvage
Reactome:R-RNO-8956321 Nucleotide salvage
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SCE-74217 Purine salvage
Reactome:R-CEL-15869 Nucleotide metabolism
Reactome:R-DME-15869 Nucleotide metabolism
Reactome:R-HSA-5668914 Diseases of metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-SCE-15869 Nucleotide metabolism
Reactome:R-SPO-8956321 Nucleotide salvage
Reactome:R-CEL-1430728 Metabolism
Reactome:R-CEL-8956321 Nucleotide salvage
Reactome:R-DME-8956321 Nucleotide salvage
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-15869 Nucleotide metabolism
Reactome:R-MMU-15869 Nucleotide metabolism
Reactome:R-RNO-15869 Nucleotide metabolism
Reactome:R-SCE-8956321 Nucleotide salvage
Reactome:R-SPO-74217 Purine salvage
WikiPathways:WP4792 Purine metabolism
WikiPathways:WP4224 Purine metabolism and related disorders
PathBank:SMP0120670 Adenylosuccinate Lyase Deficiency
PathBank:SMP0000167 Adenylosuccinate Lyase Deficiency
PathBank:SMP0000220 Xanthine Dehydrogenase Deficiency (Xanthinuria)
PathBank:SMP0000512 Xanthinuria Type I
PathBank:SMP0000536 Mitochondrial DNA Depletion Syndrome-3
PathBank:SMP0120669 Adenosine Deaminase Deficiency
PathBank:SMP0120673 AICA-Ribosiduria
PathBank:SMP0120709 Gout or Kelley-Seegmiller Syndrome
PathBank:SMP0120717 Xanthine Dehydrogenase Deficiency (Xanthinuria)
PathBank:SMP0120797 Xanthinuria Type II
PathBank:SMP0120821 Myoadenylate Deaminase Deficiency
PathBank:SMP0000050 Purine Metabolism
PathBank:SMP0000144 Adenosine Deaminase Deficiency
PathBank:SMP0000203 Molybdenum Cofactor Deficiency
PathBank:SMP0000428 Mercaptopurine Action Pathway
PathBank:SMP0000535 Adenine Phosphoribosyltransferase Deficiency (APRT)
PathBank:SMP0120728 Lesch-Nyhan Syndrome (LNS)
PathBank:SMP0120752 Molybdenum Cofactor Deficiency
PathBank:SMP0120756 Purine Nucleoside Phosphorylase Deficiency
PathBank:SMP0120796 Xanthinuria Type I
PathBank:SMP0120820 Mitochondrial DNA Depletion Syndrome
PathBank:SMP0000365 Gout or Kelley-Seegmiller Syndrome
PathBank:SMP0000210 Purine Nucleoside Phosphorylase Deficiency
PathBank:SMP0000430 Thioguanine Action Pathway
PathBank:SMP0000513 Xanthinuria Type II
PathBank:SMP0000537 Myoadenylate Deaminase Deficiency
PathBank:SMP0087332 Purine Metabolism
PathBank:SMP0120819 Adenine Phosphoribosyltransferase Deficiency (APRT)
PathBank:SMP0000364 Lesch-Nyhan Syndrome (LNS)
PathBank:SMP0000168 AICA-Ribosiduria
PathBank:SMP0000427 Azathioprine Action Pathway
PathBank:SMP0087239 Purine Metabolism