EC: 2.3.1.47

8-amino-7-oxononanoate synthase (6-carboxyhexanoyl-[acyl-carrier protein]:L-alanine C-carboxyhexanoyltransferase (decarboxylating))

enzyme lambda metabolic reaction experiment
uniprot:Q5SHZ8 [8-amino-7-oxononanoate synthase(Enzyme) wildtype]

6_Carboxyhexanoyl_CoA + L_Alanine -> Coenzyme_A + CO2 + 8_Amino_7_oxononanoate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM potassium phosphate, 0.1 mM pyridoxal 5'-phosphate
PH: 6
Temperature: 70
uniprot:Q5SHZ8 [8-amino-7-oxononanoate synthase(Enzyme) wildtype]

6_Carboxyhexanoyl_CoA + L_Alanine -> 8_Amino_7_oxononanoate + CO2 + Coenzyme_A		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM potassium phosphate, 0.1 mM pyridoxal 5'-phosphate
PH: 6
Temperature: 70
uniprot:P22806 [8-amino-7-oxononanoate synthase(Enzyme) wildtype]

6_Carboxyhexanoyl_CoA + L_Alanine -> 8_Amino_7_oxononanoate + Coenzyme_A + CO2		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate
PH: 7
Temperature: 25
uniprot:P22806 [8-amino-7-oxononanoate synthase(Enzyme) wildtype]

L_Alanine + 6_Carboxyhexanoyl_CoA -> Coenzyme_A + CO2 + 8_Amino_7_oxononanoate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate
PH: 7
Temperature: 25

Pathways

pathway id name
BioCyc:CAULONA1000_PWY-3701 biotin biosynthesis II
BioCyc:MTBCDC1551_PWY-6578 8-amino-7-oxononanoate biosynthesis III
BioCyc:ECOL199310_PWY-6578 8-amino-7-oxononanoate biosynthesis III
BioCyc:BSUB_PWY-6578 8-amino-7-oxononanoate biosynthesis III
BioCyc:CAULONA1000_BIOTIN-SYNTHESIS-PWY biotin biosynthesis I
BioCyc:META_PWY-6578 8-amino-7-oxononanoate biosynthesis III
BioCyc:ANTHRA_PWY-6578 8-amino-7-oxononanoate biosynthesis III
BioCyc:BSUB_THREONINE-DEG2-PWY L-threonine degradation II
PathBank:SMP0000785 Biotin Metabolism
PathBank:SMP0121292 Threonine Biosynthesis
PathBank:SMP0121263 Biotin Metabolism