EC: 2.5.1.31

ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] ((2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 8 isopentenyl units))

enzyme lambda metabolic reaction experiment
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM KOH-HEPES, 50 mM KCl, 0.5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM KOH-HEPES, 50 mM KCl, 0.5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant H199A/E213A]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM KOH-HEPES, 50 mM KCl, 0.5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant H199A]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM KOH-HEPES, 50 mM KCl, 0.5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant H43A]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM KOH-HEPES, 50 mM KCl, 0.5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant H199A/E213A]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM KOH-HEPES, 50 mM KCl, 0.5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant H43A]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM KOH-HEPES, 50 mM KCl, 0.5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant H199A]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 100 mM KOH-HEPES, 50 mM KCl, 0.5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 25
uniprot:Q88VJ8 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.5% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.5% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

n_n_n_n_Isopentenyl_diphosphate + Neryl_diphosphate -> n_n_n_n_Diphosphate + Polyprenyl_diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.5% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

n_n_n_n_Isopentenyl_diphosphate + Geranyl_diphosphate -> Polyprenyl_diphosphate + n_n_n_n_Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.5% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [Cardiolipin]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [Myristic acid]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.05% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.5% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.05% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.2% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.5% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

Geranylgeranyl_diphosphate + n_n_n_n_Isopentenyl_diphosphate -> n_n_n_n_Diphosphate + Polyprenyl_diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.5% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

7 n_n_n_n_Isopentenyl_diphosphate + cis,trans,trans_Geranylgeranyl_diphosphate -> Undecaprenyl_diphosphate + 7 n_n_n_n_Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.5% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

n_n_n_n_Isopentenyl_diphosphate + cis,trans_Farnesyl_diphosphate -> Polyprenyl_diphosphate + n_n_n_n_Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2, 0.5% Triton X-100
PH: 7.5
Temperature: 35
uniprot:Q88VJ8 [Cardiolipin]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.10 M Tris, 0.2 mM MgCl2
PH: 7.5
Temperature: 35
uniprot:P60472 [Mg2+]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Hepes, 50 M KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [Mg2+]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Hepes, 50 M KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [Mg2+]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Hepes, 50 M KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant S71A]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant S71A]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) wildtype]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant N74A]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant R77A]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant W75A]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant N74A]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant E81A]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant R77A]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant W75A]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific](Enzyme) mutant E81A]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 100 mM KOH-Hepes, 50 mM KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [Mg2+]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Hepes, 50 M KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [Mg2+]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Hepes, 50 M KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [Mg2+]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Hepes, 50 M KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [Mg2+]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> 8 n_n_n_n_Diphosphate + Undecaprenyl_diphosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Hepes, 50 M KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [Mg2+]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Hepes, 50 M KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [Mg2+]

trans,trans_Farnesyl_diphosphate + 8 n_n_n_n_Isopentenyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Hepes, 50 M KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25
uniprot:P60472 [Mg2+]

8 n_n_n_n_Isopentenyl_diphosphate + trans,trans_Farnesyl_diphosphate -> Undecaprenyl_diphosphate + 8 n_n_n_n_Diphosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Hepes, 50 M KCl, 0.5 mM MgCl2, 0.1% Triton X-100
PH: 7.5
Temperature: 25

Pathways

pathway id name
BioCyc:ECO_POLYISOPRENSYN-PWY polyisoprenoid biosynthesis (E. coli)
BioCyc:ECOL199310_PWY-5785 di-trans,poly-cis-undecaprenyl phosphate biosynthesis
BioCyc:ECOL316407_PWY-5785 di-trans,poly-cis-undecaprenyl phosphate biosynthesis
BioCyc:META_PWY-5785 di-trans,poly-cis-undecaprenyl phosphate biosynthesis
BioCyc:ECO_PWY-5785 di-trans,poly-cis-undecaprenyl phosphate biosynthesis
BioCyc:ECOL199310_POLYISOPRENSYN-PWY polyisoprenoid biosynthesis (E. coli)
BioCyc:ECOL316407_POLYISOPRENSYN-PWY polyisoprenoid biosynthesis (E. coli)
BioCyc:META_POLYISOPRENSYN-PWY polyisoprenoid biosynthesis (E. coli)
PathBank:SMP0000974 Secondary Metabolites: Methylerythritol Phosphate and Polyisoprenoid Biosynthesis